Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Kangfu, Chen"'
Autor:
Kangfu Chen, Bill T. V. Duong, Sharif U. Ahmed, Piriththiv Dhavarasa, Zongjie Wang, Mahmoud Labib, Connor Flynn, Jingya Xu, Yi Y. Zhang, Hansen Wang, Xiaolong Yang, Jagotamoy Das, Hossein Zargartalebi, Yuan Ma, Shana O. Kelley
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Exosomal PD-L1 (exoPD-L1) has recently received significant attention as a biomarker predicting immunotherapeutic responses involving the PD1/PD-L1 pathway. However, current technologies for exosomal analysis rely primarily on bulk measureme
Externí odkaz:
https://doaj.org/article/db1a84b8a6c24aea94bb88980dd20cfc
Publikováno v:
Bioengineering, Vol 11, Iss 6, p 542 (2024)
The characterization of individual cells within heterogeneous populations (e.g., rare tumor cells in healthy blood cells) has a great impact on biomedical research. To investigate the properties of these specific cells, such as genetic biomarkers and
Externí odkaz:
https://doaj.org/article/90646c0edb2943188623adc1528b07dc
Autor:
Zongjie Wang, Kangfu Chen
Publikováno v:
Brain-X, Vol 1, Iss 3, Pp n/a-n/a (2023)
Abstract Approximately 20% of cancer patients experience brain metastases in the advanced stages as circulating tumor cells migrate to and colonize the brain microvasculature. Due to the challenges associated with biopsies, our understanding of the t
Externí odkaz:
https://doaj.org/article/57cfee76e3bb42e793a97a0c75dd6bb3
Autor:
Kangfu Chen, Zongjie Wang
Publikováno v:
Methods and Protocols, Vol 6, Iss 5, p 80 (2023)
Advancements in single-cell-related technologies have opened new possibilities for analyzing rare cells, such as circulating tumor cells (CTCs) and rare immune cells. Among these techniques, single-cell proteomics, particularly single-cell mass spect
Externí odkaz:
https://doaj.org/article/0f995d336e8d4b6abf59890eecee686d
Publikováno v:
Biosensors, Vol 13, Iss 7, p 706 (2023)
Liquid biopsy has progressed to its current use to diagnose and monitor cancer. Despite the recent advances in investigating cancer detection and diagnosis strategies, there is still a room for improvements in capturing CTCs. We developed an efficien
Externí odkaz:
https://doaj.org/article/37370da7710a470a996bcf7881bbabad
Autor:
Kangfu Chen, Zongjie Wang
Publikováno v:
Chemosensors, Vol 11, Iss 6, p 335 (2023)
Rare cells play essential roles in the initiation and progression of diseases and therefore their analysis is of great interest. The micro-magnetofluidic system is one of the emerging platforms that have been proposed for the rapid, sensitive, and co
Externí odkaz:
https://doaj.org/article/c565da036b4a4d21811f86c1d7715a27
Autor:
Shana O. Kelley, Hansen Wang, Fan Xia, Bill Duong, Lia Cardarelli, Sharif Uddin Ahmed, Kangfu Chen, Sachdev S. Sidhu, Zongjie Wang, Irene Lui, James A. Wells, Randy Atwal, Yuan Ma
Publikováno v:
ACS Nano. 15:19202-19210
Advances in single-cell level profiling of the proteome require quantitative and versatile platforms, especially for rare cell analyses such as circulating tumor cell (CTC) profiling. Here we demonstrate an integrated microfluidic chip that uses magn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcb24fcbd28a8223b115078b27f78485
https://doi.org/10.1021/acsnano.1c03935
https://doi.org/10.1021/acsnano.1c03935
Autor:
David N. Philpott, Kangfu Chen, Randy S. Atwal, Derek Li, Jessie Christie, Edward H. Sargent, Shana O. Kelley
Publikováno v:
Lab on a chip. 22(24)
High-throughput phenotypic cell sorting is critical to the development of cell-based therapies and cell screening discovery platforms. However, current cytometry platforms are limited by throughput, number of fractionated populations that can be isol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8d053aee2961fe92da6e958d169cc08
https://pubmed.ncbi.nlm.nih.gov/36382608
https://pubmed.ncbi.nlm.nih.gov/36382608
Autor:
Fan, Xia, Yuan, Ma, Kangfu, Chen, Bill, Duong, Sharif, Ahmed, Randy, Atwal, David, Philpott, Troy, Ketela, Jennifer, Pantea, Sichun, Lin, Stephane, Angers, Shana O, Kelley
Publikováno v:
Science advances. 8(35)
Circulating tumor cells (CTCs) break free from primary tumors and travel through the circulation system to seed metastatic tumors, which are the major cause of death from cancer. The identification of the major genetic factors that enhance production
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::31064af5113715452d6793d4859064e5
https://pubmed.ncbi.nlm.nih.gov/36054348
https://pubmed.ncbi.nlm.nih.gov/36054348
Autor:
Abdalla M. Abdrabou, Bill T. V. Duong, Kangfu Chen, Randy Singh Atwal, Mahmoud Labib, Sichun Lin, Stephane Angers, Shana O. Kelley
Publikováno v:
ACS central science. 8(12)
Genome-wide loss-of-function screens are critical tools to identify novel genetic regulators of intracellular proteins. However, studying the changes in the organelle-specific expression profile of intracellular proteins can be challenging due to pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ad8e988c4a5871756b826ad4f2d9b5c
https://pubmed.ncbi.nlm.nih.gov/36589880
https://pubmed.ncbi.nlm.nih.gov/36589880