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Metabolite profiling and cardiovascular event risk: A prospective study of three population-based cohorts

Autor: Würtz, P., Havulinna, A.S., Soininen, P., Tynkkynen, T., Prieto-Merino, D., Tillin, T., Ghorbani, A., Artati, A., Wang, Q., Tiainen, M., Kangas, A.J., Kettunen, J., Kaikkonen, J., Mikkilä, V., Jula, A., Kähönen, M., Lehtimäki, T., Lawlor, D.A., Gaunt, T.R., Hughes, A.D., Sattar, N., Illig, T., Adamski, J., Wang, T.J., Perola, M., Ripatti, S., Vasan, R.S., Raitakari, O.T., Gerszten, R.E., Casas, J.P., Chaturvedi, N., Ala-Korpela, M., Salomaa, V.

Publikováno v: Circulation 131, 774-785 (2015)

BACKGROUND: -High-throughput profiling of circulating metabolites may improve cardiovascular risk prediction over established risk factors. METHODS AND RESULTS: -We applied quantitative NMR metabolomics to identify biomarkers for incident cardiovascu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3474::d711dff469e8f73fa9e35561399e8510
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=43090

Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma

Autor: Chambers, J.C., Zhang, W.H., Sehmi, J., Li, X.Z., Wass, M.N., Harst, P. van der, Holm, H., Sanna, S., Kavousi, M., Baumeister, S.E., Coin, L.J., Deng, G.H., Gieger, C., Heard-Costa, N.L., Hottenga, J.J., Kuhnel, B., Kumar, V., Lagou, V., Liang, L.M., Luan, J.A., Vidal, P.M., Leach, I.M., O'Reilly, P.F., Peden, J.F., Rahmioglu, N., Soininen, P., Speliotes, E.K., Yuan, X., Thorleifsson, G., Alizadeh, B.Z., Atwood, L.D., Borecki, I.B., Brown, M.J., Charoen, P., Cucca, F., D. das, Geus, E.J.C. de, Dixon, A.L., Doering, A., Ehret, G., Eyjolfsson, G.I., Farrall, M., Forouhi, N.G., Friedrich, N., Goessling, W., Gudbjartsson, D.F., Harris, T.B., Hartikainen, A.L., Heath, S., Hirschfield, G.M., Hofman, A., Homuth, G., Hypponen, E., Janssen, H.L.A., Johnson, T., Kangas, A.J., Kema, I.P., Kuhn, J.P., Lai, S., Lathrop, M., Lerch, M.M., Li, Y., Liang, T.J., Lin, J.P., Loos, R.J.F., Martin, N.G., Moffatt, M.F., Montgomery, G.W., Munroe, P.B., Musunuru, K., Nakamura, Y., O'Donnell, C.J., Olafsson, I., Penninx, B.W., Pouta, A., Prins, B.P., Prokopenko, I., Puls, R., Ruokonen, A., Savolainen, M.J., Schlessinger, D., Schouten, J.N.L., Seedorf, U., Sen-Chowdhry, S., Siminovitch, K.A., Smit, J.H., Spector, T.D., Tan, W.T., Teslovich, T.M., Tukiainen, T., Uitterlinden, A.G., Klauw, M.M. van der, Vasan, R.S., Wallace, C., Wallaschofski, H., Wichmann, H.E., Willemsen, G., Wurtz, P., Xu, C., Yerges-Armstrong, L.M., Abecasis, G.R., Ahmadi, K.R., Boomsma, D.I., Caulfield, M., Cookson, W.O., Duijn, C.M. van, Froguel, P., Matsuda, K., McCarthy, M.I., Meisinger, C., Mooser, V., Pietilainen, K.H., Schumann, G., Snieder, H., Sternberg, M.J.E., Stolk, R.P., Thomas, H.C., Thorsteinsdottir, U., Uda, M., Waeber, G., Wareham, N.J., Waterworth, D.M., Watkins, H., Whitfield, J.B., Witteman, J.C.M., Wolffenbuttel, B.H.R., Fox, C.S., Ala-Korpela, M., Stefansson, K., Vollenweider, P., Volzke, H., Schadt, E.E., Scott, J., Jarvelin, M.R., Elliott, P., Kooner, J.S., Alcohol Genome-wide Assoc AlcGen, Diabet Genetics Replication, Genetic Invest Anthropometric, Global Lipids Genetics Consortium, Genetics Liver Dis GOLD Consortium, Int Consortium Blood Pressure ICBP, Meta-Anal Glucose Insulin-Related

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_____10693::f8a51664d6c095d2f988315718fc2e7b
https://hdl.handle.net/1887/118347

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21 COMPREHENSIVE METABOLIC PROFILING IMPROVES PREDICTION OF SUBCLINICAL ATHEROSCLEROSIS IN YOUNG ADULTS

Autor: Würtz, P., Raiko, J., Magnussen, C.G., Soininen, P., Kangas, A.J., Tynkkynen, T., Thomson, R., Laatikainen, R., Savolainen, M.J., Jula, A., Viikari, J.S., Kähönen, M., Lehtimäki, T., Juonala, M., Ala-Korpela, M., Raitakari, O.T.

Publikováno v: In Atherosclerosis (Supplements) (Component) June 2011 12(1):5-5