Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Kang-Jie Bian"'
Autor:
Qian Gao, Wei-Cheng Xu, Xuan Nie, Kang-Jie Bian, Hong-Rui Yuan, Wen Zhang, Bing-Bing Wu, Xi-Sheng Wang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-9 (2024)
Abstract The migratory insertion of metal-hydride into alkene has allowed regioselective access to organometallics, readily participating in subsequent functionalization as one conventional pathway of hydroalkylation, whereas analogous process with f
Externí odkaz:
https://doaj.org/article/090ce43e3ef145cf8ebe96f2910d0bcc
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 19, Iss 1, Pp 1225-1233 (2023)
The place of alkyl radicals in organic chemistry has changed markedly over the last several decades, evolving from challenging-to-generate “uncontrollable” species prone to side reactions to versatile reactive intermediates enabling construction
Externí odkaz:
https://doaj.org/article/086a0a51465b4820b0ea8370be59112f
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
The difunctionalization of alkenes allows for efficient construction of molecular complexity. Combining Ligand-to-Metal Charge transfer (LMCT) and Radical Ligand Transfer (RLT), the authors show a photochemical diazidation using iron salts, allowing
Externí odkaz:
https://doaj.org/article/a6f22699ed5b4c63a63e26a0ac7907f9
Autor:
Ruo-Xing Jin, Bing-Bing Wu, Kang-Jie Bian, Jian-Liang Yu, Jing-Cheng Dai, Ya-Wen Zuo, Yi-Fan Zhang, Xi-Sheng Wang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-8 (2022)
The efficient construction of trifluoromethylated alkanes bearing a CF3 chiral center is of great importance in organic synthesis. Here, the authors disclose the enantioselective syntheses of α-trifluoromethylated allylic alkanes via reductive trifl
Externí odkaz:
https://doaj.org/article/be493e5df7fa45cca79da39f622e55a4
Publikováno v:
CCS Chemistry. 4:2888-2896
The selective introduction of fluorine atoms into drug candidates has long been used as a common strategy in drug discovery. Most methods used for the synthesis of tertiary aliphatic fluorides rely...
Publikováno v:
Trends in Chemistry. 4:1062-1064
Publikováno v:
Chinese Journal of Chemistry. 40:1531-1536
Publikováno v:
Journal of the American Chemical Society. 144:6543-6550
Fluorinated motifs are frequently encountered in drugs and agrochemicals. Incorporating fluorine-containing motifs in drug candidates for lead optimization in pharmaceutical research and development has emerged as a powerful tool. The construction of
Autor:
Yuan-Bo Li, Jie Sheng, Jing-Cheng Dai, Xi-Sheng Wang, Kang-Jie Bian, Guo-Qing Cui, Yan Li, Duo-Duo Hu
Publikováno v:
Organic Letters. 23:7503-7507
The first example of copper-catalyzed ring-opening, enantioselective arylation of cyclic ketoxime esters to access ω,ω-diaryl alkyl nitriles has been developed in high yield (up to 92% yield) with excellent enantioselectivity (up to 91% ee). Side-a
Autor:
Shan-Xiu Ni, Guang-Xu Liao, Bing-Bing Wu, Ru Cui, Kang-Jie Bian, Jie Sheng, Xi-Sheng Wang, Yan He, Hui-Qi Ni
Publikováno v:
Angewandte Chemie International Edition. 60:15020-15027
Monofluorinated alkyl compounds are of great importance in pharmaceuticals, agrochemicals and materials. Herein, we describe a direct nickel-catalyzed monofluoromethylation of unactivated alkyl halides using a low-cost industrial raw material, bromof