Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Kang Xuan Jin"'
Autor:
Kang-Xuan Jin, Adam Filipczyk, Rujuan Zuo, Konstantinos Anastassiadis, Arne Klungland, Carsten Marr
Publikováno v:
Proc. Natl. Acad. Sci. U.S.A. 118:e2105192118 (2021)
N6-methyladenosine (m6A) deposition on messenger RNA (mRNA) controls embryonic stem cell (ESC) fate by regulating the mRNA stabilities of pluripotency and lineage transcription factors (TFs) [P. J. Batista etal., Cell Stem Cell 15, 707-719 (2014); Y.
Autor:
Kang-Xuan, Jin, Rujuan, Zuo, Konstantinos, Anastassiadis, Arne, Klungland, Carsten, Marr, Adam, Filipczyk
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Dynamic deposition of the N6-methyladenosine (m6A) modification on messenger RNA (mRNA) regulates pluripotency in embryonic stem cells. Reports show that depletion of m6A abundances increases the mRNA stability of pluripotency and lineag
Autor:
Kang-Xuan Jin, Rujuan Zuo, Anastassiadis, Konstantinos, Klungland, Arne, Marr, Carsten, Filipczyk, Adam
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 12/21/2021, Vol. 118 Issue 51, p1-12, 12p
Autor:
Xin Yang, Wei Wu, Wen Xiao, Xiu-Jie Wang, Chuan He, Wenjia Wang, Yu-Sheng Chen, Kang-Xuan Jin, Shuhui Song, Bao-Fa Sun, Xing Wang, Yamei Niu, Yun-Gui Yang, Xiao-Li Ping, Hyun Seok Jeong, Xu Zhao, Ying Yang, Guifang Jia, Akimitsu Okamoto, Ya-Juan Hao, Xiaomeng Ge, Yue Shi, Jannie M. Rendtlew Danielsen, Wei-Min Tong, Yu Fu, Hiroyuki Yanagisawa, Chun-Min Huang
Publikováno v:
Cell Research
The role of Fat Mass and Obesity-associated protein (FTO) and its substrate N6-methyladenosine (m6A) in mRNA processing and adipogenesis remains largely unknown. We show that FTO expression and m6A levels are inversely correlated during adipogenesis.
Autor:
Yong Sheng Wu, Yijun Qi, Zechen Chong, Ming Ming Li, Zhaoqing Ba, Tie-Shan Tang, Xingzhi Xu, Yun-Gui Yang, Ting Zhang, Jannie M. Rendtlew Danielsen, Niels Mailand, You Qi Liao, Samir Adhikari, Wei Wei, Kang Xuan Jin, Min Gao, Bing Tao Zhu, Miao Miao Li, Caixia Guo
Publikováno v:
Cell Research. 24:532-541
DNA double-strand breaks (DSBs) are highly cytotoxic lesions and pose a major threat to genome stability if not properly repaired. We and others have previously shown that a class of DSB-induced small RNAs (diRNAs) is produced from sequences around D
Autor:
Ying Yang, Ben-Zhan Zhu, Zechen Chong, Kang Xuan Jin, Shuhui Song, Ruichuan Yin, Hailin Wang, Bao-Fa Sun, Xiaoli Wang, Chao Zhao, Hua Huang, Jannie M. Rendtlew Danielsen, Maoyong Song, Yun-Gui Yang, Guoliang Xu, Guibin Jiang, Bailin Zhao, Cuiping Li, Danni Wu
Publikováno v:
Nucleic Acids Research
DNA methylation has been proven to be a critical epigenetic mark important for various cellular processes. Here, we report that redox-active quinones, a ubiquitous class of chemicals found in natural products, cancer therapeutics and environment, sti
Autor:
Anja Nilsen, Maria Olofsson, Chuan He, Kang-Xuan Jin, Ye Fu, Bo Liu, Xingzhi Xu, Ming-Ming Li, Yuehe Ding, Jannie M. Rendtlew Danielsen, Markus Fusser, Yue Shi, Yamei Niu, Yun-Gui Yang, Arne Klungland, Meng-Qiu Dong, Yong-Sheng Wu, Chun-Min Huang, Ying Lv
Publikováno v:
Nature Communications
Regulation of actomyosin dynamics by post-transcriptional modifications in cytoplasmic actin is still poorly understood. Here we demonstrate that dioxygenase ALKBH4-mediated demethylation of a monomethylated site in actin (K84me1) regulates actin–m
Autor:
Lisi Sang, Jie Hao, Ang Li, Ya-Juan Hao, Libin Wang, Li-Gang Wu, Ying Lv, Tong Chen, Ying Yang, Xu Zhao, Hailin Wang, Xiu-Jie Wang, Miao-Miao Li, Guibin Jiang, Yun-Gui Yang, Qi Zhou, Yuhuan Li, Kang-Xuan Jin, Ying Zhang, Weifang Han, Weiyi Lai, Yong-Sheng Wu, Xiao-Li Ping, Meng Wang
Publikováno v:
Cell Stem Cell. 16:338
N(6)-methyladenosine (m(6)A) has been recently identified as a conserved epitranscriptomic modification of eukaryotic mRNAs, but its features, regulatory mechanisms, and functions in cell reprogramming are largely unknown. Here, we report m(6)A modif