Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Kang Won Jang"'
Publikováno v:
Korean Journal of Thoracic and Cardiovascular Surgery, Vol 50, Iss 3, Pp 153-162 (2017)
Background: The mesenchymal-epithelial transition factor (MET) receptor can be overexpressed in solid tumors, including small cell lung cancer (SCLC). However, the molecular mechanism regulating MET stability and turnover in SCLC remains undefined.
Externí odkaz:
https://doaj.org/article/2525551a2d5449349d0c97ff01d1c368
Autor:
Byoung Chul Cho, Soonmyung Paik, Joo Hang Kim, Yong Wha Moon, Sun Min Lim, Hye Ryun Kim, Chan Woo Kang, Han Na Kang, Mi Ran Yun, Jinyoung Sohn, Min Hwan Kim, Kang Won Jang, Hwan Kim, Sung-Moo Kim
A, Lysates from MV522 cells and GSR cells were evaluated by western blotting to determine total and phosphorylated c-MET levels from the arrays in Fig. 3A. B, MV522 cells and GSR cells were cultured in control (CTL), 0.1 µM GSK2118436 (GSK), or 2 µ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2ad08a4c1e99a8eef466e436598c93d
https://doi.org/10.1158/1535-7163.22508431
https://doi.org/10.1158/1535-7163.22508431
Autor:
Byoung Chul Cho, Joo Hang Kim, Dae Joon Kim, Soonmyung Paik, Yong Wha Moon, Sun Min Lim, Hye Ryun Kim, Han Na Kang, Mi Ran Yun, Hwan Kim, Kyoung-Ho Pyo, Sung-Moo Kim, Jinyoung Sohn, Kang Won Jang, Chan Woo Kang
Supplementary Table 2. siRNA sequences
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c43856d174d4f9d1ab474d080a0971e
https://doi.org/10.1158/1535-7163.22506099
https://doi.org/10.1158/1535-7163.22506099
Autor:
Byoung Chul Cho, Soonmyung Paik, Joo Hang Kim, Yong Wha Moon, Sun Min Lim, Hye Ryun Kim, Chan Woo Kang, Han Na Kang, Mi Ran Yun, Jinyoung Sohn, Min Hwan Kim, Kang Won Jang, Hwan Kim, Sung-Moo Kim
Supplementary Table S1. Sequencing primers (Sanger) Supplementary Table S2. siRNA sequences
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e87fc33f96077f3bdf2a02734cafccb
https://doi.org/10.1158/1535-7163.22508416.v1
https://doi.org/10.1158/1535-7163.22508416.v1
Autor:
Byoung Chul Cho, Joo Hang Kim, Dae Joon Kim, Soonmyung Paik, Yong Wha Moon, Sun Min Lim, Hye Ryun Kim, Han Na Kang, Mi Ran Yun, Hwan Kim, Kyoung-Ho Pyo, Sung-Moo Kim, Jinyoung Sohn, Kang Won Jang, Chan Woo Kang
Supplementary Figure 2. Significant weight loss in LC-2/ad xenograft mice treated with vandetanib Mice bearing LC-2/ad cells were treated with vehicle only (Vehicle), dovitinib (DO 30mg/kg), dovitinib (DO 60mg/kg), or vandetanib (VA 50mg/kg) for 32da
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1197869ce5a722e8ad55404101b4ef7f
https://doi.org/10.1158/1535-7163.22506111.v1
https://doi.org/10.1158/1535-7163.22506111.v1
Autor:
Byoung Chul Cho, Soonmyung Paik, Joo Hang Kim, Yong Wha Moon, Sun Min Lim, Hye Ryun Kim, Chan Woo Kang, Han Na Kang, Mi Ran Yun, Jinyoung Sohn, Min Hwan Kim, Kang Won Jang, Hwan Kim, Sung-Moo Kim
mRNA expression levels of the indicated genes were measured by quantitative RT-PCR in MV522 cells and in GSR (Pool) cells upon treatment with control siRNA (siRNA control) or RIP2 siRNA (siRIP2).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ffc1bbf96e48f2179833b18d4d5a5df
https://doi.org/10.1158/1535-7163.22508419.v1
https://doi.org/10.1158/1535-7163.22508419.v1
Autor:
Byoung Chul Cho, Joo Hang Kim, Dae Joon Kim, Soonmyung Paik, Yong Wha Moon, Sun Min Lim, Hye Ryun Kim, Han Na Kang, Mi Ran Yun, Hwan Kim, Kyoung-Ho Pyo, Sung-Moo Kim, Jinyoung Sohn, Kang Won Jang, Chan Woo Kang
Supplementary Figure 1. Supplementary Figure S1. Dovitinib inhibits RET kinase and its downstream signaling in lung cancer cells harboring RET rearrangement A, Western blot analysis of indicated markers in LC-2/ad cells after treated with indicated d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81a09d04275cdea019ac5291993957af
https://doi.org/10.1158/1535-7163.22506114.v1
https://doi.org/10.1158/1535-7163.22506114.v1
Autor:
Byoung Chul Cho, Joo Hang Kim, Dae Joon Kim, Soonmyung Paik, Yong Wha Moon, Sun Min Lim, Hye Ryun Kim, Han Na Kang, Mi Ran Yun, Hwan Kim, Kyoung-Ho Pyo, Sung-Moo Kim, Jinyoung Sohn, Kang Won Jang, Chan Woo Kang
RET rearrangement is a newly identified oncogenic mutation in lung adenocarcinoma (LADC). Activity of dovitinib (TKI258), a potent inhibitor of FGFR, VEGFR, and PDGFR, in RET-rearranged LADC has not been reported. The aims of the study are to explore
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f675499e56eb49a34408ebb2b344d76
https://doi.org/10.1158/1535-7163.c.6538293.v1
https://doi.org/10.1158/1535-7163.c.6538293.v1
Autor:
Byoung Chul Cho, Soonmyung Paik, Joo Hang Kim, Yong Wha Moon, Sun Min Lim, Hye Ryun Kim, Chan Woo Kang, Han Na Kang, Mi Ran Yun, Jinyoung Sohn, Min Hwan Kim, Kang Won Jang, Hwan Kim, Sung-Moo Kim
A, A375 cells were treated with 100 nM GSK2118436 in the absence or presence of each ligand. Cellular lysates were probed with the indicated antibodies in western blots. B, In MTT assays, A375 cells were treated in control or with 20 nM GSK2118436 af
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::457f29125a0fdb8554479f99ab97df22
https://doi.org/10.1158/1535-7163.22508425
https://doi.org/10.1158/1535-7163.22508425
Autor:
Byoung Chul Cho, Soonmyung Paik, Joo Hang Kim, Yong Wha Moon, Sun Min Lim, Hye Ryun Kim, Chan Woo Kang, Han Na Kang, Mi Ran Yun, Jinyoung Sohn, Min Hwan Kim, Kang Won Jang, Hwan Kim, Sung-Moo Kim
A, Cells were transfected for 24 h with EGFP-C1 vector, plasmids encoding RIP2-GFP, or RIP2 (S176E)-GFP (which is phosphorylated form constitutively), respectively, and treated with or without GSK2118436 for 48 h. Lysates were probed with the indicat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61459bb7dab5b2adc3d0c84eadc59ef6
https://doi.org/10.1158/1535-7163.22508422
https://doi.org/10.1158/1535-7163.22508422