Zobrazeno 1 - 10 of 75 pro vyhledávání: '"Kang Quan Hu"'
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Akademický článek
Extracellular Nicotinamide Phosphoribosyltransferase Is a Component of the Senescence-Associated Secretory Phenotype
Autor: Chisaka Kuehnemann, Kang-Quan Hu, Kayla Butera, Sandip K. Patel, Joanna Bons, Birgit Schilling, Cristina Aguayo-Mazzucato, Christopher D. Wiley
Publikováno v: Frontiers in Endocrinology, Vol 13 (2022)
Cellular senescence is a stress or damage response by which a cell adopts of state of essentially permanent proliferative arrest, coupled to the secretion of a number of biologically active molecules. This senescence-associated secretory phenotype (S
Externí odkaz: https://doaj.org/article/003825a129bd4f75b929b9148cea82e1
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2
Akademický článek
β-Cryptoxanthin Attenuates Cigarette-Smoke-Induced Lung Lesions in the Absence of Carotenoid Cleavage Enzymes (BCO1/BCO2) in Mice
Autor: Rachel A. Chiaverelli, Kang-Quan Hu, Chun Liu, Ji Ye Lim, Michael S. Daniels, Hui Xia, Jonathan Mein, Johannes von Lintig, Xiang-Dong Wang
Publikováno v: Molecules, Vol 28, Iss 3, p 1383 (2023)
High dietary intake of β-cryptoxanthin (BCX, an oxygenated provitamin A carotenoid) is associated with a lower risk of lung disease in smokers. BCX can be cleaved by β-carotene-15,15′-oxygenase (BCO1) and β-carotene-9′,10′-oxygenase (BCO2) t
Externí odkaz: https://doaj.org/article/32171c2ba4ac41ed8318abf25bb2e6c9
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7
Final Supplemental figures from β-Cryptoxanthin Reduced Lung Tumor Multiplicity and Inhibited Lung Cancer Cell Motility by Downregulating Nicotinic Acetylcholine Receptor α7 Signaling
Autor: Xiang-Dong Wang, Chun Liu, Kang-Quan Hu, Xinli Li, Benchun Miao, Anita R. Iskandar
Supplementary Figure S1. Reduction of mRNA expressions of α7-nachr by BCX supplementation, not α3-, α5-, and β4-nachr, was associated with lung tumor multiplicity. Upper panel: The statistically significant correlation between lung tumor multipli
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1dd1f8a4de2d9a018bd006160fe7415
https://doi.org/10.1158/1940-6207.22533284
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8
Data from β-Cryptoxanthin Reduced Lung Tumor Multiplicity and Inhibited Lung Cancer Cell Motility by Downregulating Nicotinic Acetylcholine Receptor α7 Signaling
Autor: Xiang-Dong Wang, Chun Liu, Kang-Quan Hu, Xinli Li, Benchun Miao, Anita R. Iskandar
Despite the consistent association between a higher intake of the provitamin A carotenoid β-cryptoxanthin (BCX) and a lower risk of lung cancer among smokers, potential mechanisms supporting BCX as a chemopreventive agent are needed. We first examin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05fd3e04048cfbbb2511e545405b211e
https://doi.org/10.1158/1940-6207.c.6547007.v1
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9
Data from Lycopene Metabolite, Apo-10′-Lycopenoic Acid, Inhibits Diethylnitrosamine-Initiated, High Fat Diet–Promoted Hepatic Inflammation and Tumorigenesis in Mice
Autor: Xiang-Dong Wang, Lynne M. Ausman, Martin S. Obin, Donald E. Smith, Chun Liu, Kang-Quan Hu, Blanche C. Ip
Obesity is associated with increased risk in hepatocellular carcinoma (HCC) development and mortality. An important disease control strategy is the prevention of obesity-related hepatic inflammation and tumorigenesis by dietary means. Here, we report
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cd7205d7e7b9895654fc87ee15822ae2
https://doi.org/10.1158/1940-6207.c.6544475
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