Zobrazeno 1 - 10
of 802
pro vyhledávání: '"Kang Qian"'
Publikováno v:
Guoji Yanke Zazhi, Vol 24, Iss 6, Pp 970-974 (2024)
AIM: To analyze the influencing factors of postoperative dry eye complication after corneal transplantation and to build a nomogram prediction model.METHODS: Clinical data were collected on 117 patients who underwent corneal transplantation at our ho
Externí odkaz:
https://doaj.org/article/9e3f6cff9ce74af6879b876ca28a4422
Autor:
Kang Qian, Wei Li, Shangqing Ren, Weilin Peng, Bei Qing, Xinlin Liu, Xiong Wei, Liang Zhu, Yapeng Wang, Xin Jin
Publikováno v:
Advanced Science, Vol 11, Iss 36, Pp n/a-n/a (2024)
Abstract Drug resistance after long‐term use of Tyrosine kinase inhibitors (TKIs) has become an obstacle for prolonging the survival time of patients with clear cell renal cell carcinoma (ccRCC). Here, genome‐wide CRISPR‐based screening to reve
Externí odkaz:
https://doaj.org/article/95bd18839c4745f4947a5dc59661117f
Autor:
Kang Qian, Peng Yang, Yixian Li, Ran Meng, Yunlong Cheng, Lingling Zhou, Jing Wu, Shuting Xu, Xiaoyan Bao, Qian Guo, Pengzhen Wang, Minjun Xu, Dongyu Sheng, Qizhi Zhang
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 19, Iss 4, Pp 100938- (2024)
Alzheimer's disease is a neurodegenerative disease induced by multiple interconnected mechanisms. Peptide drug candidates with multi-modal efficacy generated from fusion strategy are suitable for addressing multi-facet pathology. However, clinical tr
Externí odkaz:
https://doaj.org/article/403f74994e394d2e9ed2d13b852fc61f
Autor:
Yixian Li, Peng Yang, Ran Meng, Shuting Xu, Lingling Zhou, Kang Qian, Pengzhen Wang, Yunlong Cheng, Dongyu Sheng, Minjun Xu, Tianying Wang, Jing Wu, Jinxu Cao, Qizhi Zhang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 3, Pp 1380-1399 (2024)
Intraneuronal dysproteostasis and extraneuronal microenvironmental abnormalities in Alzheimer's disease (AD) collectively culminate in neuronal deterioration. In the context of AD, autophagy dysfunction, a multi-link obstacle involving autophagy down
Externí odkaz:
https://doaj.org/article/8bd04ee938174169b40471e454fdf68d
Autor:
Xiaoyan Bao, Kang Qian, Mengjiao Xu, Yi Chen, Hao Wang, Ting Pan, Zhengyi Wang, Ping Yao, Li Lin
Publikováno v:
Journal of Nanobiotechnology, Vol 21, Iss 1, Pp 1-15 (2023)
Abstract Background Oral administration offered a painless way and improved compliance for diabetics. However, the emerging GLP-1 analog peptide drugs for diabetes primarily rely on the injection route, and the development of oral dosage forms was ha
Externí odkaz:
https://doaj.org/article/bed2d15d99fe44b38b3421364305fd05
Autor:
Shuting Xu, Peng Yang, Kang Qian, Yixian Li, Qian Guo, Pengzhen Wang, Ran Meng, Jing Wu, Jinxu Cao, Yunlong Cheng, Minjun Xu, Qizhi Zhang
Publikováno v:
Bioactive Materials, Vol 11, Iss , Pp 300-316 (2022)
Compromised autophagy and defective lysosomal clearance significantly contribute to impaired neuronal proteostasis, which represents a hallmark of Alzheimer's disease (AD) and other age-related neurodegenerative disorders. Growing evidence has implic
Externí odkaz:
https://doaj.org/article/38cdd5f5995b4da78d49ad7b81c7193b
Autor:
Kang Qian, Jiajing Wang, Jing Rao, Peng Zhang, Yaqiang Sun, Wenqing Hu, Jie Hao, Xiaobing Jiang, Peng Fu
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
ObjectiveMicroelectrode recording (MER) guided subthalamic nucleus deep brain stimulation (STN-DBS) under local anesthesia (LA) is widely applied in the management of advanced Parkinson's disease (PD). Whereas, awake DBS under LA is painful and burde
Externí odkaz:
https://doaj.org/article/53394a7c3007490ea074512f4c068d52
We present an all-fiber, fully open Fabry-Perot interferometer (FPI) cavity that is suitable for fluidic measurement applications. Fabrication of the FPI involves the alignment and bonding of three optical fiber sections using either ceramic glue or
Externí odkaz:
http://arxiv.org/abs/2408.07354
Autor:
Kang Qian, Chuansheng Nie, Wende Zhu, Hongyang Zhao, Fangcheng Zhang, Haijun Wang, Xiaobing Jiang
Publikováno v:
Frontiers in Surgery, Vol 9 (2022)
BackgroundTuberculum sellae meningioma (TSM), a common benign tumor in the sellae region, usually causes neurological deficits, such as vision impairment, by squeezing the peripheral neurovascular structures. Surgical management is recommended as the
Externí odkaz:
https://doaj.org/article/08fc5e3b341544099748fd2c4a1577f0
Publikováno v:
Gong-kuang zidonghua, Vol 47, Iss 2, Pp 6-12 (2021)
In order to solve the problems of low output power, poor protection effect, and slow dynamic response speed of existing intrinsically safe power supply, a high-power intrinsically safe power supply based on fault current change rate is designed. The
Externí odkaz:
https://doaj.org/article/2622694e1fdb4589922131296839a424