Zobrazeno 1 - 10
of 174
pro vyhledávání: '"Kang Ho Kim"'
Autor:
Peter M Masschelin, Pradip Saha, Scott A Ochsner, Aaron R Cox, Kang Ho Kim, Jessica B Felix, Robert Sharp, Xin Li, Lin Tan, Jun Hyoung Park, Liping Wang, Vasanta Putluri, Philip L Lorenzi, Alli M Nuotio-Antar, Zheng Sun, Benny Abraham Kaipparettu, Nagireddy Putluri, David D Moore, Scott A Summers, Neil J McKenna, Sean M Hartig
Publikováno v:
eLife, Vol 12 (2023)
Flavin adenine dinucleotide (FAD) interacts with flavoproteins to mediate oxidation-reduction reactions required for cellular energy demands. Not surprisingly, mutations that alter FAD binding to flavoproteins cause rare inborn errors of metabolism (
Externí odkaz:
https://doaj.org/article/efada387f39b4eff8fe4ccda1c65b1f6
Autor:
Mi Jeong Heo, Ji Ho Suh, Sung Ho Lee, Kyle L. Poulsen, Yu A. An, Bhagavatula Moorthy, Sean M. Hartig, David D. Moore, Kang Ho Kim
Publikováno v:
Molecular Metabolism, Vol 72, Iss , Pp 101717- (2023)
Objective: Mitophagy removes damaged mitochondria to maintain cellular homeostasis. Aryl hydrocarbon receptor (AhR) expression in the liver plays a crucial role in supporting normal liver functions, but its impact on mitochondrial function is unclear
Externí odkaz:
https://doaj.org/article/13b0b290b21c4a599188bb3f6154ef68
Autor:
Erini Nessim Kostandy, Ji Ho Suh, Xiangjun Tian, Beanna Okeugo, Erin Rubin, Sara Shirai, Meng Luo, Christopher M. Taylor, Kang Ho Kim, J. Marc Rhoads, Yuying Liu
Publikováno v:
Nutrients, Vol 16, Iss 4, p 511 (2024)
The probiotic Limosilactobacillus reuteri DSM 17938 produces anti-inflammatory effects in scurfy (SF) mice, a model characterized by immune dysregulation, polyendocrinopathy, enteropathy, and X-linked inheritance (called IPEX syndrome in humans), cau
Externí odkaz:
https://doaj.org/article/6d5affb187e440c0b6be0ae086568d02
Publikováno v:
Frontiers in Nutrition, Vol 9 (2022)
The nutrient sensing nuclear receptor peroxisome proliferator-activated receptor-α (PPARα) regulates the host response to short-term fasting by inducing hepatic transcriptional programming of ketogenesis, fatty acid oxidation and transport, and aut
Externí odkaz:
https://doaj.org/article/8f2c2982b4484a6898eabbdb9134805f
Autor:
Lindsey S. Treviño, Jianrong Dong, Ahkilesh Kaushal, Tiffany A. Katz, Rahul Kumar Jangid, Matthew J. Robertson, Sandra L. Grimm, Chandra Shekar R. Ambati, Vasanta Putluri, Aaron R. Cox, Kang Ho Kim, Thaddeus D. May, Morgan R. Gallo, David D. Moore, Sean M. Hartig, Charles E. Foulds, Nagireddy Putluri, Cristian Coarfa, Cheryl Lyn Walker
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Early life exposure to environmental stressors, including endocrine disrupting chemicals (EDCs), can impact health later in life. Here, the authors show that neonatal EDC exposure in rats causes epigenetic reprogramming in the liver, which is transcr
Externí odkaz:
https://doaj.org/article/1bd07351812944de819b5ad960475b3b
Autor:
Aaron R. Cox, Natasha Chernis, Kang Ho Kim, Peter M. Masschelin, Pradip K. Saha, Shawn M. Briley, Robert Sharp, Xin Li, Jessica B. Felix, Zheng Sun, David D. Moore, Stephanie A. Pangas, Sean M. Hartig
Publikováno v:
Molecular Metabolism, Vol 48, Iss , Pp 101221- (2021)
Objective: White adipose tissue (WAT) expansion regulates energy balance and overall metabolic homeostasis. The absence or loss of WAT occurring through lipodystrophy and lipoatrophy contributes to the development of hepatic steatosis and insulin res
Externí odkaz:
https://doaj.org/article/b4e693534e744d1f9c3d3f322b504585
Autor:
Natalia Gomez-Ospina, Carol J. Potter, Rui Xiao, Kandamurugu Manickam, Mi-Sun Kim, Kang Ho Kim, Benjamin L. Shneider, Jennifer L. Picarsic, Theodora A. Jacobson, Jing Zhang, Weimin He, Pengfei Liu, A. S. Knisely, Milton J. Finegold, Donna M. Muzny, Eric Boerwinkle, James R. Lupski, Sharon E. Plon, Richard A. Gibbs, Christine M. Eng, Yaping Yang, Gabriel C. Washington, Matthew H. Porteus, William E. Berquist, Neeraja Kambham, Ravinder J. Singh, Fan Xia, Gregory M. Enns, David D. Moore
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
Neonatal cholestasis is a result of elevated bile acid levels, and is associated with mutations in genes regulating bile acid homeostasis. Here the authors identify mutations in the bile acid sensing farnesoid X receptor in four individuals with neon
Externí odkaz:
https://doaj.org/article/e73281ebd5d34ed788509187b61992e0
Publikováno v:
Journal of Lipid Research, Vol 51, Iss 12, Pp 3425-3433 (2010)
Liver X receptor (LXR), a sterol-activated nuclear hormone receptor, has been implicated in cholesterol and fatty acid homeostasis via regulation of reverse cholesterol transport and de novo fatty acid synthesis. LXR is also involved in immune respon
Externí odkaz:
https://doaj.org/article/75861f75919b4b8ea3924b361849213c
Autor:
Yeri Lee, Kang Ho Kim, Dong Geon Kim, Hee Jin Cho, Yeonghwan Kim, Jinguen Rheey, Kayoung Shin, Yun Jee Seo, Yeon-Sook Choi, Jung-Il Lee, Jeongwu Lee, Kyeung Min Joo, Do-Hyun Nam
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0137703 (2015)
Glioblastoma (GBM) is the most aggressive and most lethal brain tumor. As current standard therapy consisting of surgery and chemo-irradiation provides limited benefit for GBM patients, novel therapeutic options are urgently required. Forkhead box M1
Externí odkaz:
https://doaj.org/article/bf32ec9cfbbb4ceab8cf481937a7900f
Autor:
Kyeung Min Joo, Juyoun Jin, Bong Gu Kang, Se Jeong Lee, Kang Ho Kim, Heekyoung Yang, Young-Ae Lee, Yu Jin Cho, Yong-Seok Im, Dong-Sup Lee, Do-Hoon Lim, Dong Hyun Kim, Hong-Duck Um, Sang-Hun Lee, Jung-Ii Lee, Do-Hyun Nam
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e25936 (2012)
Radiation therapy is an indispensable therapeutic modality for various brain diseases. Though endogenous neural stem cells (NSCs) would provide regenerative potential, many patients nevertheless suffer from radiation-induced brain damage. Accordingly
Externí odkaz:
https://doaj.org/article/ceb9df566d4842df86d8c8d57455b5af