Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen

Autor: Menden M, Wang D, Mason M, Szalai B, Bulusu K, Guan Y, Yu T, Kang J, Jeon M, Wolfinger R, Nguyen T, Zaslavskiy M, Jang I, Ghazoui Z, Ahsen M, Vogel R, Neto E, Norman T, Tang E, Garnett M, Di Veroli G, Fawell S, Stolovitzky G, Guinney J, Dry J, Saez-Rodriguez J, Abante J, Abecassis B, Aben N, Aghamirzaie D, Aittokallio T, Akhtari F, Al-lazikani B, Alam T, Allam A, Allen C, de Almeida M, Altarawy D, Alves V, Amadoz A, Anchang B, Antolin A, Ash J, Aznar V, Ba-alawi W, Bagheri M, Bajic V, Ball G, Ballester P, Baptista D, Bare C, Bateson M, Bender A, Bertrand D, Wijayawardena B, Boroevich K, Bosdriesz E, Bougouffa S, Bounova G, Brouwer T, Bryant B, Calaza M, Calderone A, Calza S, Capuzzi S, Carbonell-Caballero J, Carlin D, Carter H, Castagnoli L, Celebi R, Cesareni G, Chang H, Chen G, Chen H, Cheng L, Chernomoretz A, Chicco D, Cho K, Cho S, Choi D, Choi J, Choi K, Choi M, De Cock M, Coker E, Cortes-Ciriano I, Cserzo M, Cubuk C, Curtis C, Van Daele D, Dang C, Dijkstra T, Dopazo J, Draghici S, Drosou A, Dumontier M, Ehrhart F, Eid F, ElHefnawi M, Elmarakeby H, van Engelen B, Engin H, de Esch I, Evelo C, Falcao A, Farag S, Fernandez-Lozano C, Fisch K, Flobak A, Fornari C, Foroushani A, Fotso D, Fourches D, Friend S, Frigessi A, Gao F, Gao X, Gerold J, Gestraud P, Ghosh S, Gillberg J, Godoy-Lorite A, Godynyuk L, Godzik A, Goldenberg A, Gomez-Cabrero D, Gonen M, de Graaf C, Gray H, Grechkin M, Guimera R, Guney E, Haibe-Kains B, Han Y, Hase T, He D, He L, Heath L, Hellton K, Helmer-Citterich M, Hidalgo M, Hidru D, Hill S, Hochreiter S, Hong S, Hovig E, Hsueh Y, Hu Z, Huang J, Huang R, Hunyady L, Hwang J, Hwang T, Hwang W, Hwang Y, Isayev O, Walk O, Jack J, Jahandideh S, Ji J, Jo Y, Kamola P, Kanev G, Karacosta L, Karimi M, Kaski S, Kazanov M, Khamis A, Khan S, Kiani N, Kim A, Kim J, Kim K, Kim S, Kim Y, Kirk P, Kitano H, Klambauer G, Knowles D, Ko M, Kohn-Luque A, Kooistra A, Kuenemann M, Kuiper M, Kurz C, Kwon M, van Laarhoven T, Laegreid A, Lederer S, Lee H, Lee J, Lee Y, Leppaho E, Lewis R, Li J, Li L, Liley J, Lim W, Lin C, Liu Y, Lopez Y, Low J, Lysenko A, Machado D, Madhukar N, De Maeyer D, Malpartida A, Mamitsuka H, Marabita F, Marchal K, Marttinen P, Mason D, Mazaheri A, Mehmood A, Mehreen A, Michaut M, Miller R, Mitsopoulos C, Modos D, Van Moerbeke M, Moo K, Motsinger-Reif A, Movva R, Muraru S, Muratov E, Mushthofa M, Nagarajan N, Nakken S, Nath A, Neuvial P, Newton R, Ning Z, De Niz C, Oliva B, Olsen C, Palmeri A, Panesar B, Papadopoulos S, Park J, Park S, Pawitan Y, Peluso D, Pendyala S, Peng J, Perfetto L, Pirro S, Plevritis S, Politi R, Poon H, Porta E, Prellner I, Preuer K, Pujana M, Ramnarine R, Reid J, Reyal F, Richardson S, Ricketts C, Rieswijk L, Rocha M, Rodriguez-Gonzalvez C, Roell K, Rotroff D, de Ruiter J, Rukawa P, Sadacca B, Safikhani Z, Safitri F, Sales-Pardo M, Sauer S, Schlichting M, Seoane J, Serra J, Shang M, Sharma A, Sharma H, Shen Y, Shiga M, Shin M, Shkedy Z, Shopsowitz K, Sinai S, Skola D, Smirnov P, Soerensen I, Soerensen P, Song J, Song S, Soufan O, Spitzmueller A, Steipe B, Suphavilai C, Tamayo S, Tamborero D, Tang J, Tanoli Z, Tarres-Deulofeu M, Tegner J, Thommesen L, Tonekaboni S, Tran H, De Troyer E, Truong A, Tsunoda T, Turu G, Tzeng G, Verbeke L, Videla S, Vis D, Voronkov A, Votis K, Wang A, Wang H, Wang P, Wang S, Wang W, Wang X, Wennerberg K, Wernisch L, Wessels L, van Westen G, Westerman B, White S, Willighagen E, Wurdinger T, Xie L, Xie S, Xu H, Yadav B, Yau C, Yeerna H, Yin J, Yu M, Yun S, Zakharov A, Zamichos A, Zanin M, Zeng L, Zenil H, Zhang F, Zhang P, Zhang W, Zhao H, Zhao L, Zheng W, Zoufir A, Zucknick M, AstraZeneca-Sanger Drug Combinatio

Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Nature Communications
Nature Communications, 10, 2674
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
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Nature Communications, 10, pp. 1-17
Nature Communications 10, 2674 (2019). doi:10.1038/s41467-019-09799-2
Dipòsit Digital de la UB
Universidad de Barcelona
Nature communications, 10 (1
AstraZeneca-Sanger Drug Combination DREAM Consortium 2019, ' Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen ', Nature Communications, vol. 10, no. 1, 2674 . https://doi.org/10.1038/s41467-019-09799-2
Nature Communications, 10:2674. Nature Publishing Group
NATURE COMMUNICATIONS
Nature Communications, 10, 1-17
Nature communications, vol 10, iss 1
Menden, M P, Wang, D, Mason, M J, Szalai, B, Bulusu, K C, Guan, Y, Yu, T, Kang, J, Jeon, M, Wolfinger, R, Nguyen, T, Zaslavskiy, M, AstraZeneca-Sanger Drug Combination DREAM Consortium, Jang, I S, Ghazoui, Z, Ahsen, M E, Vogel, R, Neto, E C, Norman, T, Tang, E K Y, Garnett, M J, Veroli, G Y D, Fawell, S, Stolovitzky, G, Guinney, J, Dry, J R & Saez-Rodriguez, J 2019, ' Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen ', Nature Communications, vol. 10, no. 1, 2674 . https://doi.org/10.1038/s41467-019-09799-2
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
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Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Nature Communications, 10(1):2674. Nature Publishing Group
Recercat. Dipósit de la Recerca de Catalunya

PubMed: 31209238
The effectiveness of most cancer targeted therapies is short-lived. Tumors often develop resistance that might be overcome with drug combinations. However, the number of possible combinations is vast, necessitating data-driven a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1827ac4799243e82b5025526f2e5a77a
http://link.springer.com/article/10.1038/s41467-019-09799-2

1.15 - Structural Chemogenomics Databases to Navigate Protein–Ligand Interaction Space

Autor: Kanev, G. K., Kooistra, A. J., I.J.P. de Esch, Graaf, C.

Publikováno v: Kanev, G K, Kooistra, A J, de Esch, I J P & de Graaf, C 2017, 1.15-Structural Chemogenomics Databases to Navigate Protein–Ligand Interaction Space . in 1.15-Structural Chemogenomics Databases to Navigate Protein–Ligand Interaction Space . Comprehensive Medicinal Chemistry III edn, vol. 1, Elsvier, pp. 444-471 .
Vrije Universiteit Amsterdam
1.15-Structural Chemogenomics Databases to Navigate Protein–Ligand Interaction Space, 1(Comprehensive Medicinal Chemistry III), 444-471

Structural chemogenomics databases allow the integration and exploration of heterogeneous genomic, structural, chemical, and pharmacological data in order to extract useful information that is applicable for the discovery of new protein targets and b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::51e7f72e5c8d9211343e2adcf37ecb18
https://hdl.handle.net/1871.1/484ee8ad-f0a0-4ab9-b6a0-57a8f047677a

International symposium: 'Evolution of permian marine biota,' and problems concerning permian sections in the type region

Autor: Chuvashov B., Bogoslovskaya M., Grunt T., Esaulova N., Kanev G., Leonova T., Chermnykh V.

Publikováno v: SCOPUS08695938-1997-5-1-SID24744453366

The main results of the International Symposium "Evolution of Permian Marine Biota," are presented. The Artinskian to Ufimian part of the section at the Kozhim River (Polar Urals) is briefly described including its paleontological characteristics. Po

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::67c6d78a7d6fa1940a11f17811155dad
https://openrepository.ru/article?id=710047

Discovery of Paleozoic spores in the central part of the synclinorium of the Vetrenyy belt of the Baltic Shield.

Autor: Danilov, M. A., Kanev, G. V.

Publikováno v: International Geology Review; Oct1979, Vol. 21 Issue 10, p1127-1130, 4p

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