Výsledky vyhledávání - "Kanemitsu Matsunaga"

Interindividual variation of serum haloperidol concentrations in Japanese patients - clinical considerations on steady-state serum level-dose ratios

Autor: Takako Maki, Ritsuko Ichimaru, Yoshinobu Goto, Shun Higuchi, Motoaki Anai, Miho Yukawa, Eiji Yukawa, Kanemitsu Matsunaga

Publikováno v: Journal of Clinical Pharmacy and Therapeutics. 28:97-101

Summary Objective: Marked interpatient variability in haloperidol (HAL) level–dose (L/D) ratios makes it difficult to use the administered dose for predicting serum concentrations. Objective: To investigate the effect of dose, age, total body weigh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cc53261a48287edde0995eb9b49ffa13
https://doi.org/10.1046/j.1365-2710.2003.00460.x

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Population pharmacokinetics of haloperidol using routine clinical pharmacokinetic data in Japanese patients

Autor: Tsuyoshi Hokazono, Yoshinobu Goto, Shun Higuchi, Takako Maki, Motoaki Anai, Shigehiro Ohdo, Ritsuko Ichimaru, Kanemitsu Matsunaga, Miho Yukawa, Eiji Yukawa

Publikováno v: Clinical pharmacokinetics. 41(2)

To clarify the observed variability of haloperidol disposition in patients with psychiatric disorders.Retrospective population pharmacokinetic study.218 Japanese patients aged 16 to 82 years who provided 391 serum haloperidol concentrations.Routine c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e8c8312380e7f463629aa55cb24907e
https://pubmed.ncbi.nlm.nih.gov/11888334

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Epidemiologic investigation of the relative clearance of haloperidol by mixed-effect modeling using routine clinical pharmacokinetic data in Japanese patients

Autor: Ritsuko Ichimaru, Kanemitsu Matsunaga, Shun Higuchi, Tsuyoshi Hokazono, Miho Yukawa, Akiko Funakoshi, Takako Maki, Eiji Yukawa, Yoshinobu Goto, Motoaki Anai, Shigehiro Ohdo

Publikováno v: Journal of clinical psychopharmacology. 20(6)

The steady-state trough concentrations of haloperidol were studied to clarify the role of the characteristics of Japanese patients in estimating haloperidol dosing regimens by using routine therapeutic drug-monitoring data. Nonlinear mixed-effects mo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f21d9d5fd7fe8c70a388b11f85800ef
https://pubmed.ncbi.nlm.nih.gov/11763020

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