Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Kanemasa Katsu"'
Publikováno v:
Antimicrobial Agents and Chemotherapy. 40:2237-2242
ER-30346 is a novel oral triazole with a broad spectrum of potent activity against a wide range of fungi. ER-30346, with MICs at which 90% of the strains tested are inhibited (MIC90s) ranging from 0.025 to 0.78 microgram/ml, was 4 to 32 times more ac
Autor:
Naoaki Watanabe, Kanemasa Katsu
Publikováno v:
The Journal of Antibiotics. 46:1707-1715
Potent antistaphylococcal activity was conferred on E1077 by the introduction of the propenylammonium group at the 3-position in the cephem nucleus and of the fluoromethoxyimino group in the 7 beta-side chain. Antistaphylococcal activity was more mar
Autor:
Atsushi Kamada, Ryoichi Hiruma, Motosuke Yamanaka, Masanobu Sasho, Isao Sugiyama, Akihiko Tsuruoka, Shigeto Negi, Itaru Tsukada, Kanemasa Katsu, Yuuki Komatsu, Yoshimasa Machida
Publikováno v:
ChemInform. 26
Publikováno v:
Journal of Antimicrobial Chemotherapy. 30:633-641
Three hundred and thirty-four recent clinical isolates of Pseudomonas aeruginosa were examined for susceptibility to cefclidin, cefepime, and cefpirome. Of these strains, 28.7% were resistant to ceftazidime, and 23.4% were resistant to imipenem. Abou
Publikováno v:
Antimicrobial agents and chemotherapy. 41(2)
ER-35786 is a new parenteral 1 beta-methyl carbapenem with a broad antibacterial spectrum and a potent antipseudomonal activity. It showed high in vitro activity, comparable to those of meropenem and a new carbapenem, BO-2727, against methicillin-sus
Publikováno v:
Antimicrobial agents and chemotherapy. 40(10)
ER-30346 is a novel oral triazole with a broad spectrum of potent activity against a wide range of fungi. In the present study, we investigated the therapeutic effects of oral ER-30346 on experimental local infections caused by Aspergillus fumigatus,
Autor:
Shigeto Negi, Atsushi Kamada, Ryoichi Hiruma, Motosuke Yamanaka, Akihiko Tsuruoka, Manabu Sasho, Isao Sugiyama, Yuki Komatsu, Kanemasa Katsu, Itaru Tsukada, Yoshimasa Machida
Publikováno v:
The Journal of antibiotics. 47(12)
In an effort to find a new oral cephalosporin with well-balanced antibacterial spectrum, good oral absorbability and long plasma half-life, a series of oxyimino aminothiazolyl 3-[(E)- or (Z)-N-substituted carbamoyloxy]propenyl cephems was synthesized
Autor:
Atsushi Kamada, Isao Sugiyama, Manabu Sasho, Motosuke Yamanaka, Yoshimasa Machida, Ryoichi Hiruma, Akihiko Tsuruoka, Shigeto Negi, Yuki Komatsu, Kanemasa Katsu, Itaru Tsukada
Publikováno v:
The Journal of antibiotics. 47(12)
The synthesis and antibacterial activities of 7 beta-[2-(2-aminothiazol-4-yl)-2-hydroxyiminoacetamido]-3-N,N - dimethylcarbamoyloxymethyl-3-cephem-4-carboxylic acid (E1100) and its analogs are described, as well as oral absorbability and in vivo acti
Autor:
Naoaki Watanabe, Kanemasa Katsu
Publikováno v:
The Journal of antimicrobial chemotherapy. 30(4)
The bactericidal activity of cefclidin (E1040), a new cephalosporin, against Pseudomonas aeruginosa was compared with that of ceftazidime and imipenem in an in-vitro model in which antibiotic concentration was varied continuously. A two-compartment o
Autor:
Kanemasa Katsu, Naoaki Watanabe
Publikováno v:
The Journal of antibiotics. 45(8)
The bactericidal activity of cefclidin (E1040), a new cephalosporin, against a clinical strain of Citrobacter freundii was compared with that of ceftazidime in a two-compartment in vitro pharmacokinetic model system designed to simulate plasma concen