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pro vyhledávání: '"Kanellos, Georgios"'
Explainable AI constitutes a fundamental step towards establishing fairness and addressing bias in algorithmic decision-making. Despite the large body of work on the topic, the benefit of solutions is mostly evaluated from a conceptual or theoretical
Externí odkaz:
http://arxiv.org/abs/2107.08045
Autor:
Kanellos, Georgios
Actin cytoskeletal regulation is of critical importance for a number of diverse cellular functions, including cell motility, endocytosis, cell division and transcription. Tight regulation of actin is critical for many aspects of cancer biology and in
Externí odkaz:
https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.726603
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Publikováno v:
Workshop on bias and fairness in AI at ECMLPKDD
Communications in Computer and Information Science ISBN: 9783030937355
Communications in Computer and Information Science
Communications in Computer and Information Science-Machine Learning and Principles and Practice of Knowledge Discovery in Databases
Communications in Computer and Information Science ISBN: 9783030937355
Communications in Computer and Information Science
Communications in Computer and Information Science-Machine Learning and Principles and Practice of Knowledge Discovery in Databases
Akademický článek
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Autor:
Kanellos, Georgios, Zhou, Jing, Patel, Hitesh, Ridgway, Rachel A., Huels, David, Gurniak, Christine B., Sandilands, Emma, Carragher, Neil O., Sansom, Owen J., Witke, Walter, Brunton, Valerie G., Frame, Margaret C.
Publikováno v:
Cell Reports, Vol 13, Iss 9, Pp 1949-1964 (2015)
Kanellos, G, Zhou, J, Patel, H, Ridgway, R A, Huels, D, Gurniak, C B, Sandilands, E, Carragher, N O, Sansom, O J, Witke, W, Brunton, V G & Frame, M C 2015, ' ADF and Cofilin1 Control Actin Stress Fibers, Nuclear Integrity, and Cell Survival ', Cell Reports, vol. 13, no. 9, pp. 1949–1964 . https://doi.org/10.1016/j.celrep.2015.10.056
Kanellos, G, Zhou, J, Patel, H, Ridgway, R A, Huels, D, Gurniak, C B, Sandilands, E, Carragher, N O, Sansom, O J, Witke, W, Brunton, V G & Frame, M C 2015, ' ADF and Cofilin1 Control Actin Stress Fibers, Nuclear Integrity, and Cell Survival ', Cell Reports, vol. 13, no. 9, pp. 1949–1964 . https://doi.org/10.1016/j.celrep.2015.10.056
SummaryGenetic co-depletion of the actin-severing proteins ADF and CFL1 triggers catastrophic loss of adult homeostasis in multiple tissues. There is impaired cell-cell adhesion in skin keratinocytes with dysregulation of E-cadherin, hyperproliferati
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Autor:
Vande Voorde J; Cancer Research UK Beatson Institute, Glasgow, UK. j.vandevoorde@beatson.gla.ac.uk., Steven RT; National Physical Laboratory, London, UK., Najumudeen AK; Cancer Research UK Beatson Institute, Glasgow, UK., Ford CA; Cancer Research UK Beatson Institute, Glasgow, UK., Dexter A; National Physical Laboratory, London, UK., Gonzalez-Fernandez A; National Physical Laboratory, London, UK., Nikula CJ; National Physical Laboratory, London, UK., Xiang Y; Department of Metabolism Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, UK., Ford L; Department of Metabolism Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, UK., Maneta Stavrakaki S; Department of Metabolism Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, UK., Gilroy K; Cancer Research UK Beatson Institute, Glasgow, UK., Zeiger LB; Cancer Research UK Beatson Institute, Glasgow, UK.; School of Cancer Sciences, University of Glasgow, Glasgow, UK., Pennel K; School of Cancer Sciences, University of Glasgow, Glasgow, UK., Hatthakarnkul P; School of Cancer Sciences, University of Glasgow, Glasgow, UK., Elia EA; National Physical Laboratory, London, UK., Nasif A; National Physical Laboratory, London, UK., Murta T; National Physical Laboratory, London, UK., Manoli E; Department of Metabolism Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, UK., Mason S; Department of Metabolism Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, UK., Gillespie M; Cancer Research UK Beatson Institute, Glasgow, UK.; School of Cancer Sciences, University of Glasgow, Glasgow, UK., Lannagan TRM; Cancer Research UK Beatson Institute, Glasgow, UK., Vlahov N; Cancer Research UK Beatson Institute, Glasgow, UK., Ridgway RA; Cancer Research UK Beatson Institute, Glasgow, UK., Nixon C; Cancer Research UK Beatson Institute, Glasgow, UK., Raven A; Cancer Research UK Beatson Institute, Glasgow, UK., Mills M; Cancer Research UK Beatson Institute, Glasgow, UK., Athineos D; Cancer Research UK Beatson Institute, Glasgow, UK., Kanellos G; Cancer Research UK Beatson Institute, Glasgow, UK., Nourse C; School of Cancer Sciences, University of Glasgow, Glasgow, UK., Gay DM; Cancer Research UK Beatson Institute, Glasgow, UK.; School of Cancer Sciences, University of Glasgow, Glasgow, UK.; Københavns Universitet, BRIC, Copenhagen, Denmark., Hughes M; Cancer Research UK Beatson Institute, Glasgow, UK., Burton A; National Physical Laboratory, London, UK., Yan B; National Physical Laboratory, London, UK., Sellers K; The Francis Crick Institute, London, UK.; Rheos Medicines, Cambridge, MA, USA., Wu V; Department of Metabolism Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, UK., De Ridder K; Department of Human Genetics, University of Leuven, KU Leuven, Leuven, Belgium., Shokry E; Cancer Research UK Beatson Institute, Glasgow, UK., Huerta Uribe A; Cancer Research UK Beatson Institute, Glasgow, UK., Clark W; Cancer Research UK Beatson Institute, Glasgow, UK., Clark G; Cancer Research UK Beatson Institute, Glasgow, UK., Kirschner K; School of Cancer Sciences, University of Glasgow, Glasgow, UK., Thienpont B; Department of Human Genetics, University of Leuven, KU Leuven, Leuven, Belgium., Li VSW; The Francis Crick Institute, London, UK., Maddocks ODK; School of Cancer Sciences, University of Glasgow, Glasgow, UK., Barry ST; Bioscience, Early Oncology, AstraZeneca, Cambridge, UK., Goodwin RJA; Imaging and Data Analytics, Clinical Pharmacology and Safety Sciences, R&D, AstraZeneca, Cambridge, UK.; Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK., Kinross J; Department of Metabolism Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, UK., Edwards J; School of Cancer Sciences, University of Glasgow, Glasgow, UK., Yuneva MO; The Francis Crick Institute, London, UK., Sumpton D; Cancer Research UK Beatson Institute, Glasgow, UK., Takats Z; Department of Metabolism Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, UK.; Biological Mass Spectrometry, Rosalind Franklin Institute, Didcot, UK., Campbell AD; Cancer Research UK Beatson Institute, Glasgow, UK., Bunch J; National Physical Laboratory, London, UK.; Department of Metabolism Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, UK.; Biological Mass Spectrometry, Rosalind Franklin Institute, Didcot, UK., Sansom OJ; Cancer Research UK Beatson Institute, Glasgow, UK. o.sansom@beatson.gla.ac.uk.; School of Cancer Sciences, University of Glasgow, Glasgow, UK. o.sansom@beatson.gla.ac.uk.
Publikováno v:
Nature metabolism [Nat Metab] 2023 Aug; Vol. 5 (8), pp. 1303-1318. Date of Electronic Publication: 2023 Aug 14.