Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Kane McQuaid"'
Autor:
Benjamin J. Pages, Sarah P. Gurung, Kane McQuaid, James P. Hall, Christine J. Cardin, John A. Brazier
Publikováno v:
Frontiers in Chemistry, Vol 7 (2019)
A spectroscopic study of the interactions of Λ- and Δ-[Ru(phen)2(dppz)]2+ with i-motif DNA containing thymine loops of various lengths. In the presence of i-motifs, the luminescence of the Λ enantiomer was enhanced much more than the Δ. Despite t
Externí odkaz:
https://doaj.org/article/aebe21fc890c4d8ba760a90996ef0758
Autor:
Christine J. Cardin, Holly Abell, Thomas Sorensen, Kane McQuaid, John A. Brazier, James P. Hall, Graeme Winter, Sarah P. Gurung, David R. Allan, David J. Cardin
Publikováno v:
Angewandte Chemie International Edition. 58:9881-9885
Using X-ray crystallography, we show an enantiospecificity in DNA G-quadruplex binding, using the complexes Λ/∆-[Ru(TAP)2(dppz-11-CN)]2+ (TAP=1,4,5,8-tetraazaphenanthrene) containing the dppz (dipyridophenazine) ligand, paralleling the specificity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40157d90f7531fa3b9b0da8d9ca3da80
https://doi.org/10.1002/anie.201814502
https://doi.org/10.1002/anie.201814502
Publikováno v:
Chemical Communications. 55:9116-9119
Λ-[Ru(TAP)2(dppz)]2+ was crystallised with the G-quadruplex-forming heptamer d(TAGGGTT). Surprisingly, even though there are four unique binding sites, the complex is not in contact with any G-quartet surface. Two complexes stabilise cavities formed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c830e323c5aa25ebb38aeb6c3d1029c
https://doi.org/10.1039/c9cc04316k
https://doi.org/10.1039/c9cc04316k
Autor:
Christine J. Cardin, Kane McQuaid
Ruthenium polypyridyl complexes have been intensively studied in many laboratories around the world for their potential applications in chemotherapy, including photodynamic therapy, and as useful DNA probes and sensors in cells. This chapter discusse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e83f1ad572a539a37ce08166dcfdc3c5
https://doi.org/10.1016/bs.adioch.2019.10.010
https://doi.org/10.1016/bs.adioch.2019.10.010
Publikováno v:
Chemical communications (Cambridge, England). 55(62)
Λ-[Ru(TAP)2(dppz)]2+ was crystallised with the G-quadruplex-forming heptamer d(TAGGGTT). Surprisingly, even though there are four unique binding sites, the complex is not in contact with any G-quartet surface. Two complexes stabilise cavities formed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::781000913138db1c0313de10379bf480
https://pubmed.ncbi.nlm.nih.gov/31298665
https://pubmed.ncbi.nlm.nih.gov/31298665
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 24(59)
The new complexes [Ru(TAP)2 (11-CN-dppz)]2+ , [Ru(TAP)2 (11-Br-dppz)]2+ and [Ru(TAP)2 (11,12-diCN-dppz)]2+ are reported. The addition of nitrile substituents to the dppz ligand of the DNA photo-oxidising complex [Ru(TAP)2 (dppz)]2+ promote π-stackin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::812ef081008393405756e29b04d2960a
https://pubmed.ncbi.nlm.nih.gov/30063271
https://pubmed.ncbi.nlm.nih.gov/30063271