Structural mechanism of AadA, a dual-specificity aminoglycoside adenylyltransferase from Salmonella enterica

Autor: Stern, Ana Laura, Van der Verren, Sander Egbert, Kanchugal P, Sandesh, Näsvall, Joakim, Gutiérrez-de-Terán, Hugo, Selmer, Maria

Publikováno v: In Journal of Biological Chemistry 20 July 2018 293(29):11481-11490

Oligomerization and characteristics of phosphoenolpyruvate carboxylase in Synechococcus PCC 7002.

Autor: Durall, Claudia¹, Kanchugal P., Sandesh², Selmer, Maria², Lindblad, Peter¹ peter.lindblad@kemi.uu.se

Publikováno v: Scientific Reports. 2/27/2020, Vol. 10 Issue 1, p1-12. 12p.

Antibiotic Resistance and the Cellular Currency S-adenosyl-methionine : Modification of aminoglycosides and nucleic acids

Autor: Kanchugal P, Sandesh

Streptomycin and spectinomycin are antibiotics that bind to ribosomes and inhibit protein synthesis. Common resistance mechanisms involve enzymatic modification of the two drugs by aminoglycoside nucleotidyltransferases (ANTs). The first part of this

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::84f5faaa549e3de26e02ed9680a4719c
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-408674

Structure and mechanism of a phage-encoded SAM lyase revises catalytic function of enzyme family.

Autor: Guo X; Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden., Söderholm A; Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden., Kanchugal P S; Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden., Isaksen GV; Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden.; Hylleraas Centre for Quantum Molecular Sciences, Department of Chemistry, UiT - The Arctic University of Norway, Tromsø, Norway., Warsi O; Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden., Eckhard U; Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden., Trigüis S; Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden., Gogoll A; Department of Chemistry-BMC, Uppsala University, Uppsala, Sweden., Jerlström-Hultqvist J; Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden.; Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden., Åqvist J; Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden., Andersson DI; Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden., Selmer M; Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden.

Publikováno v: ELife [Elife] 2021 Feb 10; Vol. 10. Date of Electronic Publication: 2021 Feb 10.