Predictors of increased affective symptoms and suicidal ideation during the COVID-19 pandemic: results from a large-scale study of 14 271 Thai adults.

Autor: Supasitthumrong T; Department of Psychiatry, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Bangkok, Thailand thitiporn.s@chula.ac.th., Maes M; Department of Psychiatry, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Bangkok, Thailand.; Department of Psychiatry, Medical University of Plovdiv, Plovdiv, Bulgaria.; Research Institute, Medical University of Plovdiv, Plovdiv, Bulgaria.; Cognitive Impairment and Dementia Research Unit, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.; Sichuan Provincial Center for Mental Health, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.; Key Laboratory of Psychosoamatic Medicine, Chinese Academy of Medical Sciences, Chengdu, China.; Kyung Hee University, Seoul, South Korea., Tunvirachaisakul C; Department of Psychiatry, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Bangkok, Thailand.; Cognitive Impairment and Dementia Research Unit, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand., Rungnirundorn T; Department of Psychiatry, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Bangkok, Thailand., Zhou B; Sichuan Provincial Center for Mental Health, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.; Key Laboratory of Psychosoamatic Medicine, Chinese Academy of Medical Sciences, Chengdu, China., Li J; Sichuan Provincial Center for Mental Health, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.; Key Laboratory of Psychosoamatic Medicine, Chinese Academy of Medical Sciences, Chengdu, China., Wainipitapong S; Department of Psychiatry, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Bangkok, Thailand., Ratanajaruraks A; Department of Psychiatry, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Bangkok, Thailand., Nimnuan C; Department of Psychiatry, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Bangkok, Thailand., Kanchanatawan B; Department of Psychiatry, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Bangkok, Thailand., Thompson T; Cente for Chronic Illness and Ageing, University of Greenwich, London, UK., Solmi M; Department of Child and adolescent Psychiatry, Charité Universitätsmedizin, Berlin, Germany.; Department of Psychiatry, University of Ottawa, Ottawa, Ontario, Canada.; Department of Mental Health, The Ottawa Hospital, Ottawa, Ontario, Canada.; Ottawa Hospital Research Institute (OHRI) Clinical Epidemiology Program, Ottawa, Ontario, Canada., Correll C; Department of Child and adolescent Psychiatry, Charité Universitätsmedizin, Berlin, Germany.; Department of Psychiatry, The Zucker Hillside Hospital, New York, New York, USA.; Department of Psychiatry and Molecular Medicine, Donald and Barbara Zucker School of Medicine, New York, New York, USA.; German Center for Mental Health (DZPG), partner site Berlin, Berlin, Germany.

Publikováno v: BMJ mental health [BMJ Ment Health] 2024 Feb 19; Vol. 27 (1). Date of Electronic Publication: 2024 Feb 19.

Inflammatory and Oxidative Pathways Are New Drug Targets in Multiple Episode Schizophrenia and Leaky Gut, Klebsiella pneumoniae, and C1q Immune Complexes Are Additional Drug Targets in First Episode Schizophrenia.

Autor: Maes M; Department of Psychiatry, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. dr.michaelmaes@hotmail.com.; Department of Psychiatry, Medical University of Plovdiv, Plovdiv, Bulgaria. dr.michaelmaes@hotmail.com.; IMPACT Strategic Research Center, Deakin University, Vic, Geelong, Australia. dr.michaelmaes@hotmail.com., Vojdani A; Immunosciences Lab., Inc., Los Angeles, CA, USA.; Cyrex Labs, LLC, Phoenix, AZ, USA.; Department of Preventive Medicine, Loma Linda University, Loma Linda, CA, USA., Sirivichayakul S; Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand., Barbosa DS; Health Sciences Graduate Program, Health Sciences Center, State University of Londrina, Londrina, PR, Brazil., Kanchanatawan B; Department of Psychiatry, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.

Publikováno v: Molecular neurobiology [Mol Neurobiol] 2021 Jul; Vol. 58 (7), pp. 3319-3334. Date of Electronic Publication: 2021 Mar 06.

A Generalized Cognitive Decline (GCoDe) Partly Mediates the Effects of Neuro-Immune and Neuro-Oxidative Toxicity on the Symptomatome and Lowered Quality of Life in (Deficit) Schizophrenia

Autor: Maes M, Kanchanatawan B

Recently we showed that schizophrenia and, especially, deficit schizophrenia is accompanied by neurocognitive impairments as measured with different cognitive batteries. The aim of this study was to examine whether a single trait underpins aberration

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb04ae9ebf4306c107dba924e96e4b70

Increased Levels of Plasma Tumor Necrosis Factor-α Mediate Schizophrenia Symptom Dimensions and Neurocognitive Impairments and Are Inversely Associated with Natural IgM and Paraoxonase 1 Activity

Autor: Maes A, Carvalho Af, Moreira Eg, Maes M, Sirivichayakul S, Kanchanatawan B, Matsumoto Ak, Barbosa Ds, Michelin Ap, Geffard M, de Oliveira Semeão L, de Lima Pedrão Jv

Accumulating evidence suggests that TNF-α-mediated immune-neurotoxicity contributes to cognitive impairments and the overall severity of schizophrenia (OSOS). There are no data whether peripheral IL-6 and IL-4 may affect the phenome of schizophrenia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0c277724e4d6c1ca1bda78adcb5269b
https://doi.org/10.20944/preprints201911.0135.v1

Exploring interleukin-6, lipopolysaccharide-binding protein and brain-derived neurotrophic factor following 12 weeks of adjunctive minocycline treatment for depression.

Autor: Hasebe K; IMPACT, the Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Deakin University, Geelong, Vic, Australia.; School of Medical Sciences, UNSW Sydney, Sydney, NSW, Australia., Mohebbi M; Biostatistics Unit, Faculty of Health, Deakin University, Geelong, Vic, Australia., Gray L; IMPACT, the Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Deakin University, Geelong, Vic, Australia.; Centre for Medical and Molecular Research, School of Medicine, Deakin University, Geelong, Vic, Australia.; Florey Institute for Neuroscience and Mental Health, University of Melbourne, Parkville, Vic, Australia., Walker AJ; IMPACT, the Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Deakin University, Geelong, Vic, Australia., Bortolasci CC; IMPACT, the Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Deakin University, Geelong, Vic, Australia.; Centre for Medical and Molecular Research, School of Medicine, Deakin University, Geelong, Vic, Australia., Turner A; IMPACT, the Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Deakin University, Geelong, Vic, Australia.; School of Medicine and Public Health, Faculty of Health, The University of Newcastle, Callaghan, NSW, Australia., Berk M; IMPACT, the Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Deakin University, Geelong, Vic, Australia.; Florey Institute for Neuroscience and Mental Health, University of Melbourne, Parkville, Vic, Australia.; Department of Psychiatry, Royal Melbourne Hospital, University of Melbourne, Parkville, Vic, Australia.; Orygen, The National Centre of Excellence in Youth Mental Health, Parkville, Vic, Australia.; Centre of Youth Mental Health, The University of Melbourne, Parkville, Vic, Australia., Walder K; IMPACT, the Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Deakin University, Geelong, Vic, Australia.; Centre for Medical and Molecular Research, School of Medicine, Deakin University, Geelong, Vic, Australia., Maes M; Department of Psychiatry, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand., Kanchanatawan B; Department of Psychiatry, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand., Ashton MM; IMPACT, the Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Deakin University, Geelong, Vic, Australia., Berk L; IMPACT, the Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Deakin University, Geelong, Vic, Australia.; Melbourne School of Population and Global Health, University of Melbourne, Carlton, Vic, Australia., Ng CH; Department of Psychiatry, University of Melbourne, The Melbourne Clinic, Richmond, Vic, Australia., Malhi GS; Faculty of Medicine and Health, Northern Clinical School, Department of Psychiatry, The University of Sydney, Sydney, NSW, Australia.; Academic Department of Psychiatry, Royal North Shore Hospital, Northern Sydney Local Health District, St Leonards, NSW, Australia.; CADE Clinic, Department of Psychiatry, Royal North Shore Hospital, St Leonards, NSW, Australia., Singh AB; IMPACT, the Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Deakin University, Geelong, Vic, Australia., Dean OM; IMPACT, the Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Deakin University, Geelong, Vic, Australia.; Florey Institute for Neuroscience and Mental Health, University of Melbourne, Parkville, Vic, Australia.

Publikováno v: Acta neuropsychiatrica [Acta Neuropsychiatr] 2022 Aug; Vol. 34 (4), pp. 220-227. Date of Electronic Publication: 2021 Dec 23.