Výsledky vyhledávání - "Kanchan Sarda"

Akademický článek

Dickkopf homolog 3 (DKK3) plays a crucial role upstream of WNT/β-CATENIN signaling for Sertoli cell mediated regulation of spermatogenesis.

Autor: Deepika Sharma Das, Neerja Wadhwa, Neetu Kunj, Kanchan Sarda, Bhola Shankar Pradhan, Subeer S Majumdar

Publikováno v: PLoS ONE, Vol 8, Iss 5, p e63603 (2013)

Testicular Sertoli cells (Sc) are main somatic component of seminiferous tubules that govern the differentiation of germ cells (Gc) and provide them physical support. Sc are the target of follicle stimulating hormone (FSH) and testosterone (T) which

Externí odkaz: https://doaj.org/article/fe96ecdb058f4e4d95963104761f88bd

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Stem cell/cellular interventions in human spinal cord injury: Is it time to move from guidelines to regulations and legislations? Literature review and Spinal Cord Society position statement

Autor: Erkan Kaptanoglu, Kanchan Sarda, Abhishek Srivastava, Susan Charlifue, S L Yadav, Bibhudendu Mohapatra, Harvinder Singh Chhabra, M Gourie-Devi, Kedar Phadke, Geeta Jotwani

Publikováno v: European Spine Journal. 28:1837-1845

In preclinical studies, many stem cell/cellular interventions demonstrated robust regeneration and/or repair in case of SCI and were considered a promising therapeutic candidate. However, data from clinical studies are not robust. Despite lack of sub

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aad657a165c035412dc68f38b3106715
https://doi.org/10.1007/s00586-019-06003-3

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Low Levels of Gαs and Ric8b in Testicular Sertoli Cells May Underlie Restricted FSH Action During Infancy in Primates

Autor: Subeer S. Majumdar, Mukkesh Gautam, S. Basu, Hironmoy Sarkar, Bhola Shankar Pradhan, Yendrembam Sangeeta Devi, Kanchan Sarda, Perumal Nagarajan, Indrashis Bhattacharya

Publikováno v: Endocrinology. 156:1143-1155

FSH acts via testicular Sertoli cells (Sc) bearing FSH receptor (FSH-R) for regulating male fertility. Despite an adult-like FSH milieu in infant boys and monkeys, spermatogenesis is not initiated until the onset of puberty. We used infant and pubert

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c96747ca215bab86cb910354297c006
https://doi.org/10.1210/en.2014-1746

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Stem cell therapy in spinal trauma: Does it have scientific validity?

Autor: Harvinder Singh Chhabra, Kanchan Sarda

Publikováno v: Indian Journal of Orthopaedics, Vol 49, Iss 1, Pp 56-71 (2015)
Indian Journal of Orthopaedics

Stem cell-based interventions aim to use special regenerative cells (stem cells) to facilitate neuronal function beyond the site of the injury. Many studies involving animal models of spinal cord injury (SCI) suggest that certain stem cell-based ther

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0506c22c9e6018a3519b9b7a0662fd4d
https://doi.org/10.4103/0019-5413.143913

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Defective Wnt3 expression by testicular Sertoli cells compromise male fertility

Autor: Subeer S. Majumdar, Abul Usmani, S. Basu, Rajesh Kumar Sarkar, Kanchan Sarda, Satya Pal Arya, Bhola Shankar Pradhan, Nirmalya Ganguli, Mansi Shukla, Surendra Singh, Kamal Mandal

Publikováno v: Cell and tissue research. 371(2)

Testicular Sertoli cells make a niche for the division and differentiation of germ cells. Sertoli cells respond to increased follicle-stimulating hormone (FSH) and testosterone (T) levels at the onset of puberty by producing paracrine factors which a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbda0ebc3899ebe91b7c48bdba29e3ad
https://pubmed.ncbi.nlm.nih.gov/29064078

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Clinical translation of stem cell based interventions for spinal cord injury - Are we there yet?

Autor: Harvinder Singh Chhabra, Kanchan Sarda

Publikováno v: Advanced drug delivery reviews. 120

Recent advances in basic science in research related to spinal cord injury (SCI) and regeneration have led to a variety of novel experimental therapeutics designed to promote functionally effective axonal regrowth and sprouting. Stem cell and other c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0be4761d74b110ee7545e6f651664b7
https://pubmed.ncbi.nlm.nih.gov/28964881

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Follicle-Stimulating Hormone-Independent Functions of Primate Sertoli Cells: Potential Implications in the Diagnosis and Management of Male Infertility

Autor: Perumal Nagarajan, Kanchan Sarda, Benjamin Stephen, Subeer S. Majumdar, Yendrembam Sangeeta Devi

Publikováno v: The Journal of Clinical Endocrinology & Metabolism. 91:1062-1068

FSH is known to augment the production of essential germ cell (Gc) survival factors, lactate and estradiol, by Sertoli cells (Sc) of 18-d-old pubertal rats. However, the failure of gonadotropin and androgen treatment to initiate spermatogenesis in te

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c268656574466b3e4c782b41a15867c3
https://doi.org/10.1210/jc.2005-2072

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Autologous bone marrow cell transplantation in acute spinal cord injury--an Indian pilot study

Autor: Kanchan Sarda, G M Sangodimath, R Sharawat, Vikas Tandon, Harvinder Singh Chhabra, Ankur Nanda, Mohit Arora, V Singh

Publikováno v: Spinal cord. 54(1)

Phase- I/II, prospective, randomized, single-blind, controlled pilot study. To determine the safety and feasibility of autologous bone marrow transplantation in patients with acute spinal cord injury (SCI) via two routes of transplantation as compare

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb7e90da9909026a235dc086fa9c022e
https://pubmed.ncbi.nlm.nih.gov/26282492

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