Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Kanchan Hajela"'
Autor:
Jyoti Bala Kaushal, Pushplata Sankhwar, Suparna Kumari, Pooja Popli, Vinay Shukla, Mohd. Kamil Hussain, Kanchan Hajela, Anila Dwivedi
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)
Abstract The present study was undertaken to explore the functional involvement of Hh signaling and its regulatory mechanism in endometrial hyperplasia. Differential expression of Hh signaling molecules i.e., Ihh, Shh, Gli1 or Gsk3β was observed in
Externí odkaz:
https://doaj.org/article/b450ef7fc3ed46729056d20d1427d9c6
Autor:
Ruchi Saxena, Vishal Chandra, Murli Manohar, Kanchan Hajela, Utsab Debnath, Yenamandra S Prabhakar, Karan Singh Saini, Rituraj Konwar, Sandeep Kumar, Kaling Megu, Bal Gangadhar Roy, Anila Dwivedi
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66246 (2013)
Inhibition of epidermal growth factor receptor (EGFR) signaling is considered to be a promising treatment strategy for estrogen receptor (ER)-negative breast tumors. We have investigated here the anti-breast cancer properties of a novel anti-prolifer
Externí odkaz:
https://doaj.org/article/6857c3de7aa34bcc9c0118c41f4072ec
Publikováno v:
ChemistrySelect. 3:3318-3323
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2ac3de02a37f52d63cce6aa67adadbb
https://doi.org/10.1002/slct.201703192
https://doi.org/10.1002/slct.201703192
Autor:
Kanchan Hajela, Vinay Shukla, Pooja Popli, Pushplata Sankhwar, Suparna Kumari, Jyoti Bala Kaushal, Anila Dwivedi, Mohd. Kamil Hussain
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)
Scientific Reports
Scientific Reports
The present study was undertaken to explore the functional involvement of Hh signaling and its regulatory mechanism in endometrial hyperplasia. Differential expression of Hh signaling molecules i.e., Ihh, Shh, Gli1 or Gsk3β was observed in endometri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b847bd8d0b13cb6946b1f2e1c49377a
https://doaj.org/article/b450ef7fc3ed46729056d20d1427d9c6
https://doaj.org/article/b450ef7fc3ed46729056d20d1427d9c6
Autor:
Preeti Chaudhary, Ravindra K. Rawal, Ravi Shankar, Uma S. Singh, Kanchan Hajela, Rituraj Konwar
Publikováno v:
Medicinal Chemistry Research. 26:1459-1468
A series of triaryl-substituted hydrazones as structural acyclic prototypes were synthesized and screened for anti-proliferative activity against breast (Michigan cancer foundation-7 and MD Anderson metastatic breast-231) and uterine cancer (Ishikawa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0b9f1d9368d48ee73feb7e3dc740496
https://doi.org/10.1007/s00044-017-1866-1
https://doi.org/10.1007/s00044-017-1866-1
Publikováno v:
ChemistrySelect. 1:4753-4757
A rapid and efficient metal-free synthesis of 3,5-disubstituted-1,2,4-oxadiazoles has been developed via iodine-induced oxidative cyclisation of N-acyl amidines. This eco-friendly approach allows wide functional group tolerance and results in the dir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07be65e5264d657c14384b0d22c099f8
https://doi.org/10.1002/slct.201601194
https://doi.org/10.1002/slct.201601194
Publikováno v:
ChemistrySelect. 1:4255-4264
A library of 3,4,6-triaryl-2-pyridones has been synthesized using multicomponent reaction (MCR) of substituted acetophenones, benzaldehydes and phenyl acetamides. All the synthesized compounds were evaluated for their anti-breast cancer activity, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::103123567cecb2128cc01923ed3b26fe
https://doi.org/10.1002/slct.201600893
https://doi.org/10.1002/slct.201600893
Autor:
Amit Laxmikant Deshmukh, Mohd. Kamil Hussain, Mohammad Imran Siddiqi, Sanjay Krishna, Kanchan Hajela, Deependra Kumar Singh, Pooja Maurya, Dibyendu Banerjee, Mohammad Shameem
Publikováno v:
RSC Advances. 6:94574-94587
The processes of DNA replication and repair are accomplished by the concerted action of several proteins. Among them human DNA ligases play an important role during the last step of almost all DNA replication and repair processes, where they seal the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::849fe9214ffb9a78b382f1d6fc7723e3
https://doi.org/10.1039/c6ra22364h
https://doi.org/10.1039/c6ra22364h
Autor:
Kanchan Hajela, Roshan Katekar, Athar Husain, Mohd. Kamil Hussain, Pragati Singh, Dibyendu Banerjee, Jiaur R. Gayen, Mohammed Riyazuddin, Anand P. Gupta, Minakshi Shukla, Guru R. Valicherla
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 162
S012-1332 is the first DNA ligase I inhibitor that demonstrated in vivo anti-breast cancer activity. The present study aimed to assess the in vivo pharmacokinetics of S012-1332 in rats and interpret them with in vitro findings. A sensitive and select
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67af63ff9b4bc01bf31aa41fc1d17d89
https://pubmed.ncbi.nlm.nih.gov/30265980
https://pubmed.ncbi.nlm.nih.gov/30265980
Autor:
Taran Khanam, Niyati Rai, Ravishankar Ramachandran, Nisha Yadav, Kanchan Hajela, Ankita Shukla
Publikováno v:
Organic & Biomolecular Chemistry. 13:5475-5487
DNA ligases are critical components for DNA metabolism in all organisms. NAD(+)-dependent DNA ligases (LigA) found exclusively in bacteria and certain entomopoxviruses are drawing increasing attention as therapeutic targets as they differ in their co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d0ba73b7f5250f8861bd877a73f6e01
https://doi.org/10.1039/c5ob00439j
https://doi.org/10.1039/c5ob00439j