Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Kanchan Garai"'
Autor:
Sandeep K.N. Mulukala, Shivkumar S. Irukuvajjula, Krishan Kumar, Kanchan Garai, Pannuru Venkatesu, Ramakrishna Vadrevu, Anil K. Pasupulati
Publikováno v:
Biochemistry and Biophysics Reports, Vol 23, Iss , Pp 100774- (2020)
Podocytes are crucial cells of the glomerular filtration unit and plays a vital role at the interface of the blood-urine barrier. Podocyte slit-diaphragm is a modified tight junction that facilitates size and charge-dependent permselectivity. Several
Externí odkaz:
https://doaj.org/article/fc59680df71c40e3aa3afd65a411972e
Autor:
Sara Linse, Tuomas P. J. Knowles, Subhas C. Bera, Kanchan Garai, Sourav Dasadhikari, Manuela R Zimmermann, Georg Meisl, Shamasree Ghosh
Publikováno v:
Journal of the American Chemical Society. 143:16621-16629
The formation of amyloid fibrils and oligomers is a hallmark of several neurodegenerative disorders, including Alzheimer's disease (AD), and contributes to the disease pathway. To progress our understanding of these diseases at a molecular level, it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0e5966761c53a5224f70b34ee6cf506
https://doi.org/10.1021/jacs.1c07228
https://doi.org/10.1021/jacs.1c07228
Autor:
Mithun Maddheshiya, Bankanidhi Sahoo, Sreelakshmi Cherakara, Timir Baran Sil, Kanchan Garai, S. Deepa, Neeraja Chilukoti
Publikováno v:
Biophys J
Molecular chaperone Hsp70 plays important roles in the pathology of amyloid diseases by inhibiting aberrant aggregation of proteins. However, the biophysical mechanism of the interaction of Hsp70 with the intrinsically disordered proteins (IDPs) is u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9779a2ac5937804c655eadb974aedb03
https://doi.org/10.1016/j.bpj.2020.12.019
https://doi.org/10.1016/j.bpj.2020.12.019
Autor:
Arpan Dey, Aditi Verma, Uchit Bhaskar, Vicky Vishvakarma, Mamata Kallianpur, Kanchan Garai, Odity Mukherjee, Sudipta Maiti
Publikováno v:
Biophysical Journal. 122:346a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb33e9d9890ab93b7994c894b5332b90
https://doi.org/10.1016/j.bpj.2022.11.1921
https://doi.org/10.1016/j.bpj.2022.11.1921
Publikováno v:
The FEBS Journal. 286:4737-4753
Although the interaction of apoE isoforms with amyloid-β (Aβ) peptides plays a critical role in the progression of Alzheimer's disease, how they interact with each other remains poorly understood. Here, we investigate the molecular mechanism of apo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50c11d48e7bc37db0dc7042c107599ae
https://doi.org/10.1111/febs.14988
https://doi.org/10.1111/febs.14988
Autor:
Shivkumar Sharma Irukuvajjula, Kanchan Garai, Pannuru Venkatesu, Anil Kumar Pasupulati, Sandeep K.N. Mulukala, Ramakrishna Vadrevu, Krishan Kumar
Publikováno v:
Biochemistry and Biophysics Reports
Biochemistry and Biophysics Reports, Vol 23, Iss, Pp 100774-(2020)
Biochemistry and Biophysics Reports, Vol 23, Iss, Pp 100774-(2020)
Podocytes are crucial cells of the glomerular filtration unit and plays a vital role at the interface of the blood-urine barrier. Podocyte slit-diaphragm is a modified tight junction that facilitates size and charge-dependent permselectivity. Several
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69a8650536be6fe5ca5c8c6cfea629c3
http://europepmc.org/articles/PMC7322680
http://europepmc.org/articles/PMC7322680
Autor:
Mithun Maddheshiya, Neeraja Chilukoti, Sreelakshmi Cherakara, Kanchan Garai, S. Deepa, Bankanidhi Sahoo
Molecular chaperone Hsp70 plays important roles in the pathology of amyloid diseases by inhibiting aberrant aggregation of proteins. However, mechanism of the interactions of Hsp70 with the amyloidogenic intrinsically disordered proteins (IDPs) is no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58f8fe83e44af883e41ac1783159b66b
Autor:
Manuela R. Zimmermann, Subhas C. Bera, Georg Meisl, Sourav Dasadhikari, Shamasree Ghosh, Sara Linse, Kanchan Garai, Tuomas P.J. Knowles
Publikováno v:
Biophysical Journal. 121:443a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82a5af81489fc3c99bd01381c1de3d47
https://doi.org/10.1016/j.bpj.2021.11.556
https://doi.org/10.1016/j.bpj.2021.11.556
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1860:1917-1926
Injection of exogenous insulin in the subcutaneous mass has been a proven therapy for type II diabetes. However, chronic administration of insulin often develops local amyloidosis at the injection site, pathologically known as "Insulin Ball". This re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f29347348cc68a4491e12aee04ff91b
https://doi.org/10.1016/j.bbamem.2018.02.008
https://doi.org/10.1016/j.bbamem.2018.02.008
Autor:
Swapna Bera, Janarthanan Krishnamoorthy, Ayyalusamy Ramamoorthy, Anirban Bhunia, Jeffrey R. Brender, Bernd Reif, Kanchan Garai, Timir Baran Sil, Samuel A. Kotler, Anirban Ghosh, Vanessa K. Morris
Publikováno v:
Chemical communications (Cambridge, England). 55(31)
Using NMR to probe transient binding of Aβ(1–40) monomers to fibers, we find partially bound conformations with the highest degree of interaction near F19-K28 and a lesser degree of interaction near the C-terminus (L34-G37). This represents a shif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5568d563988af938f46b3e249fe56b77
https://pubmed.ncbi.nlm.nih.gov/30917192
https://pubmed.ncbi.nlm.nih.gov/30917192