B cell clonal lineage alterations upon recombinant HIV-1 envelope immunization of rhesus macaques.

Autor: Christina Yacoob, Miles Darnell Lange, Kristen Cohen, Kanan Lathia, Junli Feng, Jolene Glenn, Sara Carbonetti, Brian Oliver, Vladimir Vigdorovich, David Noah Sather, Leonidas Stamatatos

Publikováno v: PLoS Pathogens, Vol 14, Iss 6, p e1007120 (2018)

Broadly neutralizing HIV-1 antibodies (bNAbs) isolated from infected subjects display protective potential in animal models. Their elicitation by immunization is thus highly desirable. The HIV-1 envelope glycoprotein (Env) is the sole viral target of

Externí odkaz: https://doaj.org/article/fa37eee73d4c44d781acf36dae059196

A high-resolution transcriptomic and spatial atlas of cell types in the whole mouse brain

Autor: Zizhen Yao, Cindy T. J. van Velthoven, Michael Kunst, Meng Zhang, Delissa McMillen, Changkyu Lee, Won Jung, Jeff Goldy, Aliya Abdelhak, Pamela Baker, Eliza Barkan, Darren Bertagnolli, Jazmin Campos, Daniel Carey, Tamara Casper, Anish Bhaswanth Chakka, Rushil Chakrabarty, Sakshi Chavan, Min Chen, Michael Clark, Jennie Close, Kirsten Crichton, Scott Daniel, Tim Dolbeare, Lauren Ellingwood, James Gee, Alexandra Glandon, Jessica Gloe, Joshua Gould, James Gray, Nathan Guilford, Junitta Guzman, Daniel Hirschstein, Windy Ho, Kelly Jin, Matthew Kroll, Kanan Lathia, Arielle Leon, Brian Long, Zoe Maltzer, Naomi Martin, Rachel McCue, Emma Meyerdierks, Thuc Nghi Nguyen, Trangthanh Pham, Christine Rimorin, Augustin Ruiz, Nadiya Shapovalova, Cliff Slaughterbeck, Josef Sulc, Michael Tieu, Amy Torkelson, Herman Tung, Nasmil Valera Cuevas, Katherine Wadhwani, Katelyn Ward, Boaz Levi, Colin Farrell, Carol L. Thompson, Shoaib Mufti, Chelsea M. Pagan, Lauren Kruse, Nick Dee, Susan M. Sunkin, Luke Esposito, Michael J. Hawrylycz, Jack Waters, Lydia Ng, Kimberly A. Smith, Bosiljka Tasic, Xiaowei Zhuang, Hongkui Zeng

Publikováno v: bioRxiv

The mammalian brain is composed of millions to billions of cells that are organized into numerous cell types with specific spatial distribution patterns and structural and functional properties. An essential step towards understanding brain function

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::868b57a84fc02d77229459a8318f58c5
https://europepmc.org/articles/PMC10081189/

Comparative cellular analysis of motor cortex in human, marmoset and mouse

Autor: Owen White, Kimberly A. Smith, Brian D. Aevermann, William J. Romanow, Joseph R. Ecker, Michael Tieu, Michael Hawrylycz, Sheng-Yong Niu, Brian R. Herb, Jacinta Lucero, Sten Linnarsson, Tanya L. Daigle, Christine S. Liu, Ed S. Lein, Boudewijn P. F. Lelieveldt, Zizhen Yao, Yang Eric Li, Stephan Fischer, Trygve E. Bakken, Jeremy A. Miller, C. Dirk Keene, Scott F. Owen, Wei Tian, Joshua Orvis, Nongluk Plongthongkum, Rosa Castanon, Megan Crow, Thomas Höllt, Bing Ren, Darren Bertagnolli, Weixiu Dong, Herman Tung, Baldur van Lew, Delissa McMillen, Bosiljka Tasic, Angeline Rivkin, Eran A. Mukamel, Nora Reed, Alexander Dobin, Chongyuan Luo, Patrick R. Hof, Nick Dee, Rongxin Fang, Kirsten Crichton, M. Margarita Behrens, Anna Bartlett, Renee Zhang, Olivier Poirion, Josef Sulc, Philip R. Nicovich, Rebecca D. Hodge, Evan Z. Macosko, Staci A. Sorensen, Dinh Diep, Thanh Pham, Songlin Ding, Richard H. Scheuermann, Jayaram Kancherla, Jeroen Eggermont, Seth A. Ament, Ronna Hertzano, Jeff Goldy, Christine Rimorin, Julia K. Osteen, Kimberly Siletti, Steven A. McCarroll, Hanqing Liu, C. Palmer, Saroja Somasundaram, Jonathan T. Ting, Jerold Chun, Xiaomeng Hou, Guoping Feng, Kun Zhang, Fenna M. Krienen, Blue B. Lake, Amy Torkelson, Hongkui Zeng, Sebastian Preissl, Christof Koch, Nikolas L. Jorstad, Andrew L. Ko, Héctor Corrada Bravo, Aviv Regev, Nikolai C. Dembrow, Kanan Lathia, Antonio Pinto-Duarte, Xinxin Wang, Lucas T. Graybuck, Melissa Goldman, Marmar Moussa, William J. Spain, Peter V. Kharchenko, Qiwen Hu, Adriana E. Sedeno-Cortes, Gregory D. Horwitz, Rachel A. Dalley, Anup Mahurkar, Brian E. Kalmbach, Andrew Aldridge, Jesse Gillis, Anna Marie Yanny, Joseph R. Nery, Tamara Casper, Fangming Xie, Matthew Kroll

Publikováno v: Nature, 598(7879), 111-119. NATURE PORTFOLIO
Nature
Nature: international weekly journal of science, 598(7879)

The primary motor cortex (M1) is essential for voluntary fine-motor control and is functionally conserved across mammals1. Here, using high-throughput transcriptomic and epigenomic profiling of more than 450,000 single nuclei in humans, marmoset monk

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec172c4ec74873eefac841febd1a5574
https://www.nature.com/articles/s41586-021-03465-8.pdf

Evolution of cellular diversity in primary motor cortex of human, marmoset monkey, and mouse

Autor: Trygve E. Bakken, Nikolas L. Jorstad, Qiwen Hu, Blue B. Lake, Wei Tian, Brian E. Kalmbach, Megan Crow, Rebecca D. Hodge, Fenna M. Krienen, Staci A. Sorensen, Jeroen Eggermont, Zizhen Yao, Brian D. Aevermann, Andrew I. Aldridge, Anna Bartlett, Darren Bertagnolli, Tamara Casper, Rosa G. Castanon, Kirsten Crichton, Tanya L. Daigle, Rachel Dalley, Nick Dee, Nikolai Dembrow, Dinh Diep, Song-Lin Ding, Weixiu Dong, Rongxin Fang, Stephan Fischer, Melissa Goldman, Jeff Goldy, Lucas T. Graybuck, Brian R. Herb, Xiaomeng Hou, Jayaram Kancherla, Matthew Kroll, Kanan Lathia, Baldur van Lew, Yang Eric Li, Christine S. Liu, Hanqing Liu, Jacinta D. Lucero, Anup Mahurkar, Delissa McMillen, Jeremy A. Miller, Marmar Moussa, Joseph R. Nery, Philip R. Nicovich, Joshua Orvis, Julia K. Osteen, Scott Owen, Carter R. Palmer, Thanh Pham, Nongluk Plongthongkum, Olivier Poirion, Nora M. Reed, Christine Rimorin, Angeline Rivkin, William J. Romanow, Adriana E. Sedeño-Cortés, Kimberly Siletti, Saroja Somasundaram, Josef Sulc, Michael Tieu, Amy Torkelson, Herman Tung, Xinxin Wang, Fangming Xie, Anna Marie Yanny, Renee Zhang, Seth A. Ament, M. Margarita Behrens, Hector Corrada Bravo, Jerold Chun, Alexander Dobin, Jesse Gillis, Ronna Hertzano, Patrick R. Hof, Thomas Höllt, Gregory D. Horwitz, C. Dirk Keene, Peter V. Kharchenko, Andrew L. Ko, Boudewijn P. Lelieveldt, Chongyuan Luo, Eran A. Mukamel, Sebastian Preissl, Aviv Regev, Bing Ren, Richard H. Scheuermann, Kimberly Smith, William J. Spain, Owen R. White, Christof Koch, Michael Hawrylycz, Bosiljka Tasic, Evan Z. Macosko, Steven A. McCarroll, Jonathan T. Ting, Hongkui Zeng, Kun Zhang, Guoping Feng, Joseph R. Ecker, Sten Linnarsson, Ed S. Lein

The primary motor cortex (M1) is essential for voluntary fine motor control and is functionally conserved across mammals. Using high-throughput transcriptomic and epigenomic profiling of over 450,000 single nuclei in human, marmoset monkey, and mouse

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c006cd91043481f7aee36762cca12127

A transcriptomic and epigenomic cell atlas of the mouse primary motor cortex

Autor: Cindy T. J. van Velthoven, Eran A. Mukamel, Kanan Lathia, Jeff Goldy, Elizabeth Purdom, Hanqing Liu, Zizhen Yao, Xinxin Wang, Victor Felix, Olivia Fong, Brian R. Herb, Jacinta Lucero, Elizabeth L. Dougherty, Carlo Colantuoni, Thanh Pham, Bing Ren, Valentine Svensson, Sheng-Yong Niu, Rongxin Fang, Davide Risso, Seth A. Ament, Michael Tieu, Christine Rimorin, John Ngai, Ricky S. Adkins, Sandrine Dudoit, Naeem Nadaf, Stephan Fischer, Michael Hawrylycz, Evan Z. Macosko, Anup Mahurkar, Joshua Orvis, Lior Pachter, Thuc Nghi Nguyen, Peter V. Kharchenko, Vasilis Ntranos, Bosiljka Tasic, Joshua D. Welch, Darren Bertagnolli, Charles R. Vanderburg, Yang Eric Li, Eeshit Dhaval Vaishnav, Xiaomeng Hou, Joseph R. Ecker, Delissa McMillen, Kirsten Crichton, Heather Huot Creasy, Antonio Pinto-Duarte, Josef Sulc, A. Sina Booeshaghi, Megan Crow, Chongyuan Luo, Owen White, Kimberly A. Smith, Jayaram Kancherla, Jonathan Crabtree, Herman Tung, Wayne I. Doyle, Angeline Rivkin, M. Margarita Behrens, Hongkui Zeng, Kelly Street, Amy Torkelson, Tommaso Biancalani, Julia K. Osteen, Héctor Corrada Bravo, Aviv Regev, Anna Bartlett, Olivier Poirion, Nick Dee, Qiwen Hu, Michelle G. Giglio, Z. Josh Huang, Andrew Aldridge, Ronna Hertzano, Sebastian Preissl, Matthew Kroll, Koen Van den Berge, Fangming Xie, Jesse Gillis, Joseph R. Nery, Tamara Casper, Hector Roux de Bézieux

Publikováno v: Nature
Nature, vol 598, iss 7879
NATURE

Single-cell transcriptomics can provide quantitative molecular signatures for large, unbiased samples of the diverse cell types in the brain1–3. With the proliferation of multi-omics datasets, a major challenge is to validate and integrate results

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c92cbbd62ebe063cc04fa1e4fb92393a
https://pubmed.ncbi.nlm.nih.gov/34616052