Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Kanako Shiba"'
Autor:
Tsutomu Hirano, Haruaki Kageyama, Seiji Shioda, Naoko Nonaka, Fumiko Takenoya, Satoshi Hirako, Shuji Inoue, Kanako Shiba, Nobuhiro Wada, Satoru Yamanaka, Yukinori Nogi
Publikováno v:
Scientific Reports
Galanin-like peptide (GALP) has an anti-obesity effect in rats and mice. It has been reported that the uptake of GALP by the brain is higher after intranasal administration than with intravenous injection. This study therefore aimed to clarify the ef
Autor:
Kaori Suzuki, Takanori Hishinuma, Kotaro Hama, Nariyasu Mano, Masayoshi Saito, Hiroaki Yamaguchi, Junichi Goto, Kanako Shiba, Junken Aoki, Yoshihisa Tomioka, Daisuke Saigusa, Nagisa Iida, Naoto Suzuki, Michiyo Okutani, Asuka Inoue, Tohru Kaneko
Publikováno v:
Analytical and Bioanalytical Chemistry. 403:1897-1905
We developed a liquid chromatography/electrospray ionization tandem mass spectrometry method for the simultaneous quantitative determination of C18 sphingosine (Sph), C18 dihydrosphingosine (dhSph), C18 phytosphingosine (pSph), C18 sphingosine-1-phos
Publikováno v:
FEBS Journal. 277:5006-5013
The hypothalamic neuropeptides modulate physiological activity via G protein-coupled receptors (GPCRs). Galanin-like peptide (GALP) is a 60 amino acid neuropeptide that was originally isolated from porcine hypothalamus using a binding assay for galan
Publikováno v:
International Journal of Obesity. 35:619-628
The hypothalamus has a critical role in the regulation of feeding behavior, energy metabolism and reproduction. Galanin-like peptide (GALP), a novel 60 amino-acid peptide with a nonamidated C-terminus, was first discovered in porcine hypothalamus. GA
Autor:
Yukari Date, Haruaki Kageyama, Seiji Shioda, Fumiko Takenoya, Masamitsu Nakazato, Kanako Shiba
Publikováno v:
Annals of the New York Academy of Sciences. 1200:162-169
Neuropeptide W (NPW), recently isolated from porcine hypothalamus, has been identified as the endogenous ligand for both NPBWR1 (GPR7) and NPBWR2 (GPR8), which belong to the orphan G protein-coupled receptor family. NPW is thought to play an importan
Autor:
Kei Endo, Fumiko Takenoya, Michiko Yagi, Kanako Shiba, Yukari Date, Seiji Shioda, Haruaki Kageyama, Masamitsu Nakazato, Naoko Nonaka
Publikováno v:
Neuropeptides. 44:99-106
Neuropeptide W (NPW), which was recently isolated from the porcine hypothalamus, has been identified as the endogenous ligand of the orphan G protein-coupled receptors GPR7 (NPBWR1) and GPR8 (NPBWR2). Infusion of NPW increases food intake in the ligh
Publikováno v:
Neuropeptides. 44:133-138
Ghrelin, an n-octanoylated 28-amino acid brain-gut peptide, was first isolated from extracts of porcine stomach. Ghrelin is an endogenous ligand for the growth hormone secretagogue type 1a receptor (GHS-R1a), the functionally active form of GHS-R, an
Publikováno v:
The Journal of Japanese Society of Stomatognathic Function. 16:85-92
新規Gタンパク質共役型受容体(GPCR)リガンドは脳内に広く分布し,摂食・エネルギー代謝調節を行っていることが知られている.本稿では,GPCRリガンドのうち最近発見された神経ペ
Autor:
Kanako Shiba, Rena Orman, Jason Lazar, Mark G. Stewart, Harumi Hotta, Haroon Kamran, Kiyomi Koizumi
Publikováno v:
Autonomic Neuroscience. 151:98-105
The autonomic consequences of seizures can be severe. Death can follow from autonomic overactivity that causes a parasympathetically mediated bradyarrhythmia. We studied the cardiovascular consequences of unilateral and bilateral stimulation of the d
Publikováno v:
European Journal of Pharmacology. 546:148-151
Effects of nicotine on blood flow in the olfactory bulb were examined in anesthetized rats. Nicotine administered intravenously at 100 microg/kg increased regional blood flow in the olfactory bulb, irrespective of changes in systemic arterial pressur