Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Kanako Izumi-Nagai"'
Autor:
Esaie Pierre, Scott J Robbie, Peter Adamson, Achim Hans-Peter Krauss, Meihua Ju, Kanako Izumi-Nagai, David T. Shima, David C. Gale, Yin-Shan Ng, James W B Bainbridge, Nori Nagai
Publikováno v:
The American Journal of Pathology. 185:2534-2549
Choroidal neovascularization (CNV) is a defining feature of wet age-related macular degeneration. We examined the functional role of CCR3 in the development of CNV in mice and primates. CCR3 was associated with spontaneous CNV lesions in the newly de
Publikováno v:
Acta Ophthalmologica
Autor:
Norihiro Nagai, Kazuo Tsubota, Atsuro Uchida, Yoko Ozawa, Kanako Izumi-Nagai, Hiroshi Mochimaru, Kenya Yuki, Hajime Shinoda, Takashi Koto, Misa Suzuki, Mariko Sasaki
Publikováno v:
The British Journal of Ophthalmology
Background/aims To study the initial characteristics and response to intravitreal ranibizumab (IVR) treatment of age-related macular degeneration (AMD). Methods We reviewed the clinical records of 141 eyes in 141 AMD patients who received monthly IVR
Autor:
Marisol Cano, James T. Handa, Shyam Biswal, Norihiro Nagai, Thomas W. Kensler, Michael B. Sporn, Kanako Izumi-Nagai, Masashi Fujihara, Xiaoni Kong, Rajesh K. Thimmulappa
Publikováno v:
Free Radical Biology and Medicine. 47:300-306
Uveitis is an inflammatory condition that can lead to blindness. It is therefore important to understand the pathophysiology against which to develop targeted therapy. Herein, we tested whether the oxidant-responsive transcription factor Nrf2 is invo
Autor:
Kazuo Tsubota, Yoko Ozawa, Takashi Urano, Yoshiaki Kubota, Makoto Inoue, Kousuke Noda, Toshio Suda, Yuichi Oike, Susumu Ishida, Kanako Izumi-Nagai, Norihiro Nagai
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 26:2252-2259
Background— Choroidal neovascularization (CNV) is a critical pathogenesis in age-related macular degeneration, the most common cause of blindness in the developed countries. The aim of the current study was to determine the involvement of the renin
Autor:
Atsuro Uchida, Kanako Izumi-Nagai, Yohei Tomita, Kazuo Tsubota, Misa Suzuki, Mariko Sasaki, Seiji Miyake, Hiroshi Mochimaru, Hajime Shinoda, Takashi Koto, Norihiro Nagai, Saori Kobayashi, Yoko Ozawa
Publikováno v:
Retina (Philadelphia, Pa.). 35(4)
To analyze the association between macular pigment optical density (MPOD), which reflects lutein (L), zeaxanthin (Z), and meso-zeaxanthin (MZ) in the macula, and background characteristics.Fifty-five healthy adult volunteers were analyzed. Macular pi
Autor:
Shigeaki Ohno, Shingo Satofuka, Norihiro Nagai, Kazuhiro Ohgami, Kazuo Tsubota, Yoko Ozawa, Kazuo Umezawa, Kanako Izumi-Nagai, Yuichi Oike, Susumu Ishida
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology. 27(12)
Background— Choroidal neovascularization (CNV) is a critical pathogenesis in age-related macular degeneration, the most common cause of blindness in the developed countries. The aim of the current study was to investigate the effect of lutein suppl
Autor:
Toshihide Kurihara, Kanako Izumi-Nagai, Kazuo Tsubota, Yoko Ozawa, Shingo Satofuka, Norihiro Nagai, Hajime Shinoda, Susumu Ishida, Makoto Inoue, Kousuke Noda, Yuichi Oike, Hiroshi Mochimaru, Takashi Koto
Publikováno v:
Investigative ophthalmologyvisual science. 48(9)
PURPOSE. To investigate the role of eicosapentaenoic acid (EPA), the major -3 polyunsaturated fatty acid (PUFA), in the development of choroidal neovascularization (CNV), together with underlying molecular mechanisms. METHODS. Six-week-old C57BL/6 mi
Autor:
Toshihide Kurihara, Yoko Ozawa, Yuichi Oike, Makoto Inoue, Takashi Koto, Hideyuki Okano, Norihiro Nagai, Kanako Izumi-Nagai, Shingo Satofuka, Yoshiyuki Ohsugi, Susumu Ishida, Masahiko Mihara, Kazuo Tsubota
Interleukin (IL)-6, a potent proinflammatory cytokine, is suggested to be a risk factor for choroidal neovascularization (CNV) because of its increased levels in the serum of patients with age-related macular degeneration; however, the role of IL-6 i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c40df512943b7da65938cbc5a3b0e630
https://europepmc.org/articles/PMC1899441/
https://europepmc.org/articles/PMC1899441/
Autor:
Yin-Shan Ng, Norihiro Nagai, Bo Chang, Richard Foxton, Peter Adamson, Brett Hosking, Kanako Izumi-Nagai, R.E. Hurd, David T. Shima, Pete Lundh von Leithner, Anthony P. Adamis
Publikováno v:
Investigative Opthalmology & Visual Science. 55:3709
Characterization of a mouse model of spontaneous choroidal neovascularization (sCNV) and its effect on retinal architecture and function.The sCNV mouse phenotype was characterized by using fundus photography, fluorescein angiography, confocal scannin