Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Kanako Ezaki"'
Autor:
Ryota Shizu, Kanako Ezaki, Takumi Sato, Ayaka Sugawara, Takuomi Hosaka, Takamitsu Sasaki, Kouichi Yoshinari
Publikováno v:
Cells, Vol 10, Iss 12, p 3550 (2021)
Background: PXR is a xenobiotic-responsive nuclear receptor that controls the expression of drug-metabolizing enzymes. Drug-induced activation of PXR sometimes causes drug–drug interactions due to the induced metabolism of co-administered drugs. Ou
Externí odkaz:
https://doaj.org/article/a88ff9a985334e848606428835fc8f93
Publikováno v:
International Journal of Molecular Sciences
Volume 24
Issue 4
Pages: 3953
Volume 24
Issue 4
Pages: 3953
The nuclear receptor peroxisome proliferator-activated receptor α (PPARα) is a transcription factor that controls the transcription of genes responsible for fatty acid metabolism. We have recently reported a possible drug–drug interaction mechani
Autor:
Chizuru Ishii, Yasushi Yamazoe, Shingo Arakawa, Masaaki Miyata, Taiki Abe, Kanako Ezaki, Takuomi Hosaka, Takamitsu Sasaki, Yuta Otsuka, Yuto Amaike, Ryota Shizu, Kouichi Yoshinari, Yuichiro Kanno
Publikováno v:
Molecular Pharmacology. 98:634-647
Long-term administration of some antiepileptic drugs often increases blood lipid levels. In this study, we investigated its molecular mechanism by focusing on the nuclear receptors constitutive active/androstane receptor (CAR) and peroxisome prolifer
Autor:
Yoshinari, Ryota Shizu, Kanako Ezaki, Takumi Sato, Ayaka Sugawara, Takuomi Hosaka, Takamitsu Sasaki, Kouichi
Publikováno v:
Cells; Volume 10; Issue 12; Pages: 3550
Background: PXR is a xenobiotic-responsive nuclear receptor that controls the expression of drug-metabolizing enzymes. Drug-induced activation of PXR sometimes causes drug–drug interactions due to the induced metabolism of co-administered drugs. Ou
Autor:
Ryota, Shizu, Yuta, Otsuka, Kanako, Ezaki, Chizuru, Ishii, Shingo, Arakawa, Yuto, Amaike, Taiki, Abe, Takuomi, Hosaka, Takamitsu, Sasaki, Yuichiro, Kanno, Masaaki, Miyata, Yasushi, Yamazoe, Kouichi, Yoshinari
Publikováno v:
Molecular pharmacology. 98(5)
Long-term administration of some antiepileptic drugs often increases blood lipid levels. In this study, we investigated its molecular mechanism by focusing on the nuclear receptors constitutive active/androstane receptor (CAR) and peroxisome prolifer