Zobrazeno 1 - 10
of 141
pro vyhledávání: '"Kanako, Miyano"'
Autor:
Kanako Miyano, Miki Nonaka, Masahiro Sakamoto, Mika Murofushi, Yuki Yoshida, Kyoko Komura, Katsuya Ohbuchi, Yoshikazu Higami, Hideaki Fujii, Yasuhito Uezono
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 9, p 4907 (2024)
Oxytocin, a significant pleiotropic neuropeptide, regulates psychological stress adaptation and social communication, as well as peripheral actions, such as uterine contraction and milk ejection. Recently, a Japanese Kampo medicine called Kamikihito
Externí odkaz:
https://doaj.org/article/ec821f361559442482737f9a236db69e
Autor:
Fumika Karaki, Taro Takamori, Koumei Kawakami, Sae Sakurai, Kyoko Hidaka, Kei Ishii, Tomoya Oki, Noriko Sato, Nao Atsumi, Karin Ashizawa, Ai Taguchi, Asuka Ura, Toko Naruse, Shigeto Hirayama, Miki Nonaka, Kanako Miyano, Yasuhito Uezono, Hideaki Fujii
Publikováno v:
Molecules, Vol 28, Iss 19, p 6925 (2023)
In medicinal chemistry, the copper-catalyzed click reaction is used to prepare ligand candidates. This reaction is so clean that the bioactivities of the products can be determined without purification. Despite the advantages of this in situ screenin
Externí odkaz:
https://doaj.org/article/c6cdea6301e74fd5814806febc9d810e
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-9 (2022)
Abstract Background Oral mucositis (OM) associated with cancer treatment not only impairs patients’ quality of life but also causes treatment delays or changes. This prospective exploratory study was conducted to evaluate the efficacy of Episil® o
Externí odkaz:
https://doaj.org/article/01993c7d19c44d978977954335fc06b3
Autor:
Yusuke Karasawa, Kanako Miyano, Masahiro Yamaguchi, Miki Nonaka, Keisuke Yamaguchi, Masako Iseki, Izumi Kawagoe, Yasuhito Uezono
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 12, p 9959 (2023)
Rubiscolins are naturally occurring opioid peptides derived from the enzymatic digestion of the ribulose bisphosphate carboxylase/oxygenase protein in spinach leaves. They are classified into two subtypes based on amino acid sequence, namely rubiscol
Externí odkaz:
https://doaj.org/article/2963fb3e77ee489f9acafe0ad030aada
Autor:
Eiko Uezono, Yusuke Mizobuchi, Kanako Miyano, Katsuya Ohbuchi, Hiroaki Murata, Akane Komatsu, Sei Manabe, Miki Nonaka, Takatsugu Hirokawa, Keisuke Yamaguchi, Masako Iseki, Yasuhito Uezono, Masakazu Hayashida, Izumi Kawagoe
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 9, p 8369 (2023)
Remifentanil (REM) and fentanyl (FEN) are commonly used analgesics that act by activating a µ-opioid receptor (MOR). Although optimal concentrations of REM can be easily maintained during surgery, it is sometimes switched to FEN for optimal pain reg
Externí odkaz:
https://doaj.org/article/6b2a585b9013486aa88a2d3221e978ac
Autor:
Kanako Miyano, Katsuya Ohbuchi, Yuka Sudo, Kouichiro Minami, Toru Yokoyama, Masahiro Yamamoto, Miaki Uzu, Miki Nonaka, Seiji Shiraishi, Hiroaki Murata, Yoshikazu Higami, Yasuhito Uezono
Publikováno v:
Journal of Pharmacological Sciences, Vol 143, Iss 4, Pp 320-324 (2020)
Cellular dielectric spectroscopy (CDS) is a novel technology enabling pharmacological evaluation of multiple receptor types with a label-free cell-based assay. We evaluated activities of a family of ligand-gated channels, transient receptor potential
Externí odkaz:
https://doaj.org/article/c353329a3d5446a2926a09e994c6518d
Autor:
Kanako Miyano, Seiya Hasegawa, Noriho Asai, Miaki Uzu, Wakako Yatsuoka, Takao Ueno, Miki Nonaka, Hideaki Fujii, Yasuhito Uezono
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2022)
Several clinical studies have reported that Japanese herbal medicine Hangeshashinto (HST) has beneficial effects on chemotherapy-induced oral ulcerative mucositis (OUM). Our previous research demonstrated that HST improves chemotherapy-induced OUM th
Externí odkaz:
https://doaj.org/article/6d4ab785a8704253be199f77913126c5
Autor:
Kanako Miyano, Minori Ikehata, Kaori Ohshima, Yuki Yoshida, Yasuhiro Nose, Sei-ichi Yoshihara, Katsuyuki Oki, Seiji Shiraishi, Miaki Uzu, Miki Nonaka, Yoshikazu Higami, Yasuhito Uezono
Publikováno v:
PLoS ONE, Vol 17, Iss 2 (2022)
Mesenchymal stem cells (MSCs), which are isolated from adipose tissue (AD-MSCs), umbilical cord (UC-MSCs), or bone marrow, have therapeutic potential including anti-inflammatory and immunomodulatory activities. It was recently reported that MSCs are
Externí odkaz:
https://doaj.org/article/d3c62824590b4058be9be33347c89cb9
Autor:
Yui Kuroda, Miki Nonaka, Yuji Kamikubo, Haruo Ogawa, Takashi Murayama, Nagomi Kurebayashi, Hakushun Sakairi, Kanako Miyano, Akane Komatsu, Tetsushi Dodo, Kyoko Nakano-Ito, Keisuke Yamaguchi, Takashi Sakurai, Masako Iseki, Masakazu Hayashida, Yasuhito Uezono
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 141, Iss , Pp 111800- (2021)
Background: The misuse of opioids has led to an epidemic in recent times. The endothelin A receptor (ETAR) has recently attracted attention as a novel therapeutic target to enhance opioid analgesia. We hypothesized that endothelin A receptors may aff
Externí odkaz:
https://doaj.org/article/9d6ee8e217b147f59416574fb884b2ce
Autor:
Masahiro Yamaguchi, Kanako Miyano, Shigeto Hirayama, Yusuke Karasawa, Kaori Ohshima, Eiko Uezono, Akane Komatsu, Miki Nonaka, Hideaki Fujii, Keisuke Yamaguchi, Masako Iseki, Masakazu Hayashida, Yasuhito Uezono
Publikováno v:
Molecules, Vol 27, Iss 20, p 7065 (2022)
Opioid receptors (ORs) are classified into three types (μ, δ, and κ), and opioid analgesics are mainly mediated by μOR activation; however, their use is sometimes restricted by unfavorable effects. The selective κOR agonist nalfurafine was initi
Externí odkaz:
https://doaj.org/article/a7b83951f1a546df8ff51977d03aab6c