Zobrazeno 1 - 10
of 150
pro vyhledávání: '"Kanakkanthara A"'
Autor:
Prasad, Anjali, Kanakkanthara, Arun
Publikováno v:
In Trends in Cell Biology March 2024 34(3):173-175
Autor:
Kanakkanthara, Arun, Miller, John H.
Publikováno v:
In BBA - Reviews on Cancer December 2021 1876(2)
Autor:
Arun Kanakkanthara, Catherine J. Huntoon, Xiaonan Hou, Minzhi Zhang, Ethan P. Heinzen, Daniel R. O’Brien, Ann L. Oberg, S. John Weroha, Scott H. Kaufmann, Larry M. Karnitz
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
High-grade serous ovarian cancers (HGSOCs) have defects in homologous recombination despite a lack of BRCA1/2 mutations. Here, the authors show that ZC3H18 positively regulates BRCA1 transcription and its loss causes BRCA1 promoter methylation and in
Externí odkaz:
https://doaj.org/article/cd553ee268364657964406f6c999755e
Autor:
Kanakkanthara, Arun, Jeganathan, Karthik B., Limzerwala, Jazeel F., Baker, Darren J., Hamada, Masakazu, Nam, Hyun-Ja, van Deursen, Willemijn H., Hamada, Naomi, Naylor, Ryan M., Becker, Nicole A., Davies, Brian A., van Ree, Janine H., Mer, Georges, Shapiro, Virginia S., Maher, L. James, Katzmann, David J., van Deursen, Jan M.
Publikováno v:
Science, 2016 Sep . 353(6307), 1549-1552.
Externí odkaz:
https://www.jstor.org/stable/44710710
Autor:
Larry M. Karnitz, S. John Weroha, Aaron S. Mansfield, Scott H. Kaufmann, Ann L. Oberg, George Vasmatzis, Melissa C. Larson, Husheng Ding, Rebecca L. Kelly, Amelia M. Huehls, Valentina Zanfagnin, Thomas L. Ekstrom, Xiaonan Hou, Arun Kanakkanthara
Supplementary Table 1 showing qRT-PCR primer sequences
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e2c42e300a522164db04b4b1adc7bbf
https://doi.org/10.1158/0008-5472.22582409
https://doi.org/10.1158/0008-5472.22582409
Autor:
Larry M. Karnitz, S. John Weroha, Aaron S. Mansfield, Scott H. Kaufmann, Ann L. Oberg, George Vasmatzis, Melissa C. Larson, Husheng Ding, Rebecca L. Kelly, Amelia M. Huehls, Valentina Zanfagnin, Thomas L. Ekstrom, Xiaonan Hou, Arun Kanakkanthara
PARP inhibitors (PARPi) have activity in homologous recombination (HR) repair-deficient, high-grade serous ovarian cancers (HGSOC). However, even responsive tumors develop PARPi resistance, highlighting the need to delay or prevent the appearance of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e677b242d96f856734272a99d21e154
https://doi.org/10.1158/0008-5472.c.6570575.v1
https://doi.org/10.1158/0008-5472.c.6570575.v1
Autor:
Larry M. Karnitz, S. John Weroha, Aaron S. Mansfield, Scott H. Kaufmann, Ann L. Oberg, George Vasmatzis, Melissa C. Larson, Husheng Ding, Rebecca L. Kelly, Amelia M. Huehls, Valentina Zanfagnin, Thomas L. Ekstrom, Xiaonan Hou, Arun Kanakkanthara
Supplementary Materials and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6416fe0aa2cfef5dc69fe7a060f4b72
https://doi.org/10.1158/0008-5472.22582412.v1
https://doi.org/10.1158/0008-5472.22582412.v1
Autor:
Larry M. Karnitz, S. John Weroha, Aaron S. Mansfield, Scott H. Kaufmann, Ann L. Oberg, George Vasmatzis, Melissa C. Larson, Husheng Ding, Rebecca L. Kelly, Amelia M. Huehls, Valentina Zanfagnin, Thomas L. Ekstrom, Xiaonan Hou, Arun Kanakkanthara
Supplementary Figures 1-8 with legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::546f743d48f755a6f08ab52163932073
https://doi.org/10.1158/0008-5472.22582415.v1
https://doi.org/10.1158/0008-5472.22582415.v1
Autor:
Larry M. Karnitz, Arun Kanakkanthara, Amelia M. Huehls, Nicholas M. Pathoulas, Thomas L. Ekstrom
Tumors with defective homologous recombination (HR) DNA repair are more sensitive to chemotherapies that induce lesions repaired by HR as well as PARP inhibitors (PARPis). However, these therapies have limited activity in HR-proficient cells. Accordi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::742a2455933235bb19b10a8b3d9d5865
https://doi.org/10.1158/1535-7163.c.6543424.v1
https://doi.org/10.1158/1535-7163.c.6543424.v1