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pro vyhledávání: '"Kana Saida–Tamiya"'
Autor:
Minoru Tamiya, Masaji Ishiguro, Kana Saida–Tamiya, Takaaki Kitazawa, Nobuhisa Isaka, Ayako Matsukawa, Genki Sekiya, Kohichi Kawahara, Kazunori Isobe, Akihiko Komuro
Publikováno v:
Bioorganicmedicinal chemistry letters. 29(11)
A study of the structural requirements of cholic acid derivatives as liver X receptor (LXR) ligands was performed. A model of cholenamide derivative 1 complexed with LXR showed that the C24 carbonyl oxygen forms a hydrogen bond with His435 located cl