Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Kana Kokubo"'
Autor:
Yuya Terashima, Etsuko Toda, Meiji Itakura, Mikiya Otsuji, Sosuke Yoshinaga, Kazuhiro Okumura, Francis H. W. Shand, Yoshihiro Komohara, Mitsuhiro Takeda, Kana Kokubo, Ming-Chen Chen, Sana Yokoi, Hirofumi Rokutan, Yutaka Kofuku, Koji Ohnishi, Miki Ohira, Toshihiko Iizasa, Hirofumi Nakano, Takayoshi Okabe, Hirotatsu Kojima, Akira Shimizu, Shiro Kanegasaki, Ming-Rong Zhang, Ichio Shimada, Hiroki Nagase, Hiroaki Terasawa, Kouji Matsushima
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
The cytoplasmic protein FROUNT can bind to chemokine receptors and enhance chemokine signalling. Here, the authors show that inhibiting FROUNT in macrophages either by knockdown of the gene or using the anti-alcoholism drug disulfiram, results in a r
Externí odkaz:
https://doaj.org/article/a4d75cebbb8f47a985d666129063bb6d
Autor:
Etsuko Toda, Anri Sawada, Kazuhiro Takeuchi, Kyoko Wakamatsu, Arimi Ishikawa, Naomi Kuwahara, Yurika Sawa, Saeko Hatanaka, Kana Kokubo, Kosho Makino, Hideyo Takahashi, Yoko Endo, Shinobu Kunugi, Mika Terasaki, Yasuhiro Terasaki, Kouji Matsushima, Yuya Terashima, Akira Shimizu
Publikováno v:
Kidney international. 102(6)
Activated monocytes/macrophages promote glomerular injury, including crescent formation, in anti-glomerular basement membrane (GBM) glomerulonephritis. Disulfiram, an alcohol-aversion drug, inhibits monocyte/macrophage migration by inhibiting FROUNT,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6213d490cec3b279956c5998ebb8d3ed
https://pubmed.ncbi.nlm.nih.gov/36049642
https://pubmed.ncbi.nlm.nih.gov/36049642
Autor:
Sana Yokoi, Takayoshi Okabe, Ichio Shimada, Toshihiko Iizasa, Etsuko Toda, Koji Ohnishi, Francis H. W. Shand, Shiro Kanegasaki, Hiroki Nagase, Meiji Itakura, Hirofumi Nakano, Mitsuhiro Takeda, Sosuke Yoshinaga, Miki Ohira, Ming-Rong Zhang, Kazuhiro Okumura, Yuya Terashima, Hirotatsu Kojima, Kana Kokubo, Ming Chen Chen, Mikiya Otsuji, Yoshihiro Komohara, Yutaka Kofuku, Hirofumi Rokutan, Hiroaki Terasawa, Kouji Matsushima, Akira Shimizu
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Tumor-associated macrophages affect tumor progression and resistance to immune checkpoint therapy. Here, we identify the chemokine signal regulator FROUNT as a target to control tumor-associated macrophages. The low level FROUNT expression in patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be5ea522550499798f4ebb8e0eda0242
https://doi.org/10.1038/s41467-020-14338-5
https://doi.org/10.1038/s41467-020-14338-5
Publikováno v:
Organicbiomolecular chemistry. 15(2)
A highly enantioselective amide allylation of α-iminoamides has been achieved using catalytic amounts of InCl3, ZnCl2 and a BINOL derivative. This reaction allowed facile access to a variety of amide functionalised α-methylene-γ-butyrolactams in e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::553fc1c780e05a87aa303d3753cac0e0
https://pubmed.ncbi.nlm.nih.gov/27910978
https://pubmed.ncbi.nlm.nih.gov/27910978