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Akademický článek

Construction and characterization of ribonuclease H2 C subunit-knockout NIH3T3 cells.

Autor: Haruka Hara, Haruna Yano, Kaho Akazawa, Kana Kamoda, Mako Kandabashi, Misato Baba, Teisuke Takita, Kiyoshi Yasukawa

Publikováno v: Bioscience, Biotechnology & Biochemistry; Aug2023, Vol. 87 Issue 8, p865-876, 12p

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Analysis of ribonucleotide content in the genomic DNA of ribonuclease H2 A subunit (RH2A)-knockout NIH3T3 cells after transient expression of wild-type RH2A or RH2A variants with an Aicardi-Goutières syndrome-causing mutation

Autor: Mako Kandabashi, Haruna Yano, Haruka Hara, Saori Ogawa, Kana Kamoda, Shu Ishibashi, Kohei Himeda, Misato Baba, Teisuke Takita, Kiyoshi Yasukawa

Publikováno v: Journal of biochemistry. 172(4)

Ribonuclease (RNase) H2 is involved in the removal of ribonucleotides embedded in genomic DNA. Eukaryotic RNase H2 is a heterotrimer consisting of the catalytic A subunit (RH2A) and the accessory B and C subunits. This study aimed to compare the cell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::875225761104483f599df8b598e104e2
https://pubmed.ncbi.nlm.nih.gov/35791750

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