Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Kana Iwamaru"'
Autor:
Riko Nakagawa, Hiroshi Tateishi, Mohamed O. Radwan, Takuma Chinen, Halilibrahim Ciftci, Kana Iwamaru, Nanami Baba, Yuna Tominaga, Ryoko Koga, Tsugumasa Toma, Jun-ichiro Inoue, Kazuo Umezawa, Mikako Fujita, Masami Otsuka
Publikováno v:
Chemical and Pharmaceutical Bulletin. 70:477-482
1,2-Naphthoquinone (2-NQ) is a nucleophile acceptor that non-selectively makes covalent bonds with cysteine residues in various cellular proteins, and is also found in diesel exhaust, an air pollutant. This molecule has rarely been considered as a ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6111ad96daf12673b2873fd69c29612
https://doi.org/10.1248/cpb.c21-01087
https://doi.org/10.1248/cpb.c21-01087
Autor:
Kanako Kawashima, Mayuko Hirota‐Tsukimachi, Tsugumasa Toma, Ryoko Koga, Kana Iwamaru, Yosuke Kanemaru, Misato Yanae, Ami Ahagon, Yurine Nakamura, Kensaku Anraku, Hiroshi Tateishi, Jin Gohda, Jun‐ichiro Inoue, Masami Otsuka, Mikako Fujita
Publikováno v:
Chemical biologydrug designREFERENCES. 99(4)
Various chimeric receptors have been developed and used for biological experiments. In the present study, we constructed three types of chimeric receptor activator of nuclear factor-kappa B (RANK) with the glutathione S-transferase (GST) protein in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d565023e6e2145755af3c42afc3c70bc
https://pubmed.ncbi.nlm.nih.gov/34882966
https://pubmed.ncbi.nlm.nih.gov/34882966
Autor:
Mohamed Abdel-Aziz, Mikako Fujita, Masami Otsuka, Kana Iwamaru, Mohamed O. Radwan, Hiroshi Tateishi, Ryoko Koga, Masahiro Kamo, Taha F.S. Ali, Gamal El-Din A. Abuo-Rahma, Eman A.M. Beshr, Hiromasa Kurosaki, Naomi Taira
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 30:127002
Induction of heat shock protein 70 (HSP70) is known to be effective against various diseases. We are interested in HSP70 induction capability of an antitumor antibiotic bleomycin which produces oxidative stress by iron chelate formation and oxygen ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::367dac077983f0abe33d7f059c9fd05d
https://doi.org/10.1016/j.bmcl.2020.127002
https://doi.org/10.1016/j.bmcl.2020.127002
Autor:
Mikako Fujita, Masami Otsuka, Daisuke Takaya, Ryoko Koga, Teruki Honma, Akifumi Takaori-Kondo, Taha F.S. Ali, Hiroshi Tateishi, Mohamed O. Radwan, Kana Iwamaru
Publikováno v:
Bioorganic & Medicinal Chemistry. 28:115409
In 2014, two novel and promising benzimidazole-based APOBEC3G stabilizers MM-1 and MM-2 (MMs) were uncovered with an elusive mechanism of action. Vif-APOBEC3G axis has been recognized as a novel therapeutic target for anti HIV-1 drug development. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a177b8baa385a129d06ebc9a3e247ad4
https://doi.org/10.1016/j.bmc.2020.115409
https://doi.org/10.1016/j.bmc.2020.115409
Autor:
Mikako Fujita, Masami Otsuka, Yuri Kudo, Satomi Ida, Hiromasa Kurosaki, Yoshinari Okamoto, Kana Iwamaru
Publikováno v:
Bioorganic Chemistry. 62:8-14
A tetrapeptide, l-histidyl-glycyl-glycyl-l-histidine (HGGH), was synthesized and the pUC19 plasmid DNA cleaving activity by copper(II) complex of HGGH (Cu(II)-HGGH) was investigated. Cu(II)-HGGH showed bleomycin-like DNA cleaving activity and, at 50n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b532c4db8384dacd434d9e2d609a5d2
https://doi.org/10.1016/j.bioorg.2015.06.007
https://doi.org/10.1016/j.bioorg.2015.06.007
Autor:
Kana Iwamaru, Takuichiro Hide, Yasunori Oba, Halil I. Ciftci, Yoshinari Okamoto, Mohamed Abdel-Aziz, Kazuo Umezawa, Mitsuyoshi Nakao, Masami Otsuka, Keishi Makino, Ryoko Koga, Hiromasa Kurosaki, Gamal El-Din A. Abuo-Rahma, Eman A.M. Beshr, Jun Ichi Kuratsu, Mikako Fujita, Taha F.S. Ali, Masahiro Matsumoto
Publikováno v:
Bioorganicmedicinal chemistry. 23(17)
Previously we have reported a metal chelating histidine-pyridine-histidine system possessing a trityl group on the histidine imidazole, namely HPH-2Trt, which induces apoptosis in human pancreatic adenocarcinoma AsPC-1 cells. Herein the influence of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2bc4a034913f5bac87f24a2f0f8af35
https://pubmed.ncbi.nlm.nih.gov/26260338
https://pubmed.ncbi.nlm.nih.gov/26260338