Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Kana Hoshino"'
Autor:
Soichi Yamada, Shion Miyoshi, Junko Nishio, Satoshi Mizutani, Zento Yamada, Natsuko Kusunoki, Hiroshi Sato, Yoshikazu Kuboi, Kana Hoshino-Negishi, Naoto Ishii, Toshio Imai, Tetsuo Mikami, Hiroyasu Nakano, Shinichi Kawai, Toshihiro Nanki
Publikováno v:
European Journal of Inflammation, Vol 18 (2020)
Background: Treatment for interstitial pneumonia (IP) associated with collagen diseases has not been established. There is a need to elucidate the pathogenesis of IP and develop a novel therapy. We aimed to clarify the role of chemokine (C-X3-C motif
Externí odkaz:
https://doaj.org/article/48e60c0fad3a48ec963e241e13797b31
Autor:
Nobuyuki Yasuda, Kana Hoshino-Negishi, Toshio Imai, Yoshiya Tanaka, Yoshikazu Kuboi, Fumitoshi Tago
Publikováno v:
ImmunoTargets and Therapy. 9:241-253
Rheumatoid arthritis (RA) is an autoimmune disorder that affects joints and is characterized by synovial hyperplasia and bone erosion associated with neovascularization and infiltration of proinflammatory cells. The introduction of biological disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a8142c3f128e809de5e26ac4456f887
https://doi.org/10.2147/itt.s277991
https://doi.org/10.2147/itt.s277991
Autor:
Yoshiya, Tanaka, Kana, Hoshino-Negishi, Yoshikazu, Kuboi, Fumitoshi, Tago, Nobuyuki, Yasuda, Toshio, Imai
Publikováno v:
ImmunoTargets and Therapy
Rheumatoid arthritis (RA) is an autoimmune disorder that affects joints and is characterized by synovial hyperplasia and bone erosion associated with neovascularization and infiltration of proinflammatory cells. The introduction of biological disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::46b67254c2722575053c5e546b98257c
https://pubmed.ncbi.nlm.nih.gov/33178636
https://pubmed.ncbi.nlm.nih.gov/33178636
Autor:
Miyuki Nishimura, Masayoshi Ohkuro, Tsutomu Kamisako, Akiko Hamaguchi, Kana Hoshino-Negishi, Fumihiro Sugiyama, Minoru Kumai, Jungo Kakuta, Toshio Imai, Nobuyuki Yasuda, Wataru Ikeda, Yoko Ida, Tomoya Nakatani, Naoto Ishii, Yoshikazu Kuboi
Publikováno v:
Arthritis & Rheumatology. 71:222-231
Objective To elucidate the role of the fractalkine (FKN)/CX3 CR1 pathway in joint destruction in rheumatoid arthritis. Methods We examined the effect of treatment with anti-mouse FKN (anti-mFKN) monoclonal antibody (mAb) on joint destruction and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::212b031dcc1cf1e787320b2995e8f1a3
https://doi.org/10.1002/art.40688
https://doi.org/10.1002/art.40688
Autor:
Soichi Yamada, Hiroshi Sato, Shinichi Kawai, Natsuko Kusunoki, Toshio Imai, Naoto Ishii, Tetsuo Mikami, Kana Hoshino-Negishi, Hiroyasu Nakano, Yoshikazu Kuboi, Shion Miyoshi, Toshihiro Nanki
Publikováno v:
Poster Presentations.
Background Pathological findings of interstitial pneumonia (IP) reveal the accumulation of inflammatory cells and proliferation of fibroblasts in lung tissue. Although a treatment has not yet been established for IP, particularly for IP with collagen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dfd5654c23a344f6f9a6121b5c13aa2d
https://doi.org/10.1136/annrheumdis-2019-eular.1672
https://doi.org/10.1136/annrheumdis-2019-eular.1672
Autor:
Nobuyuki Yasuda, Wataru Ikeda, Naoto Ishii, Tomoya Nakatani, Kana Hoshino-Negishi, Masayoshi Ohkuro, Yoshikazu Kuboi, Toshio Imai
Publikováno v:
SATURDAY, 15 JUNE 2019.
Background In the Phase 1/2 clinical study, E6011, a novel humanized anti-fractalkine (FKN) mAb demonstrated a promising efficacy in active RA patients who were inadequately controlled by MTX and/or TNF-α inhibitors (NCT 02196558)1.In RA joint tissu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::337be16080f8101425493a69f00d87a2
https://doi.org/10.1136/annrheumdis-2019-eular.1790
https://doi.org/10.1136/annrheumdis-2019-eular.1790
Autor:
Masao Iwata, Kenichi Nomoto, Yoichi Ozawa, Katsuhisa Suzuki, Yusuke Adachi, Kishan Agarwala, Sho Tachino, Takanori Abe, Kazuhiro Tahara, Masashi Shimizu, Youya Nakazawa, Yasuhiro Funahashi, Yukinori Minoshima, Tomomi Kawakatsu, Kana Hoshino-Negishi, Miyuki Nishimura, Ken Ito, Toshio Imai, Toshitaka Sato, Junji Matsui, Hideaki Ogasawara, Yu Kato, Yoshimasa Sakamoto
Publikováno v:
Cancer Research. 80:1485-1485
Notch4 is selectively expressed on tumor endothelial cells and hypothesized to contribute to cancer malignancy through mechanisms including tumor angiogenesis regulation and promoting drug resistance. We developed E7011, a humanized IgG2κ antibody t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a4e9f638b6b9e0abce852f1e76f284b
https://doi.org/10.1158/1538-7445.am2020-1485
https://doi.org/10.1158/1538-7445.am2020-1485
Autor:
Tomoya Nakatani, Masayoshi Ohkuro, Wataru Ikeda, Nobuyuki Yasuda, Naoto Ishii, Toshio Imai, Yoshikazu Kuboi, Kana Hoshino-Negishi
Publikováno v:
THURSDAY, 14 JUNE 2018.
Background In the Phase 1/2 clinical study, E6011, a novel humanised anti-fractalkine (FKN) mAb demonstrated a promising efficacy in active RA patients who were inadequately controlled by MTX and/or TNF-α inhibitors (NCT 02196558). FKN is expressed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2fff3900cdf8ca9890b05423a6a606e0
https://doi.org/10.1136/annrheumdis-2018-eular.4407
https://doi.org/10.1136/annrheumdis-2018-eular.4407
Autor:
Naoto Ishii, Toshio Imai, Wataru Ikeda, Nobuyuki Yasuda, Tomoya Nakatani, Masayoshi Ohkuro, Kana Hoshino-Negishi, T Yamauchi, Yoshikazu Kuboi
Publikováno v:
Poster Presentations.
Background In the Phase 1/2 clinical study, E6011, a novel humanized anti-fractalkine (FKN) monoclonal antibody (mAb) demonstrated a promising efficacy in active rheumatoid arthritis (RA) patients who were inadequately controlled by MTX and/or TNF-a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a42f2a8fcf120ec0ce5fcd37ba99f9cf
https://doi.org/10.1136/annrheumdis-2017-eular.3599
https://doi.org/10.1136/annrheumdis-2017-eular.3599
Autor:
Mary Lucas, Noreen Fertig, Shinichi Sato, Manabu Fujimoto, Fumihide Ogawa, Andrew Schnure, Kana Hoshino, Kazuhiko Takehara, Masataka Kuwana, Thomas A. Medsger, Takashi Satoh, Minoru Hasegawa, Kenzou Kaji, Yasuhito Hamaguchi
Publikováno v:
Arthritis Care & Research. 66:575-584
Objective To identify and characterize a novel systemic sclerosis (SSc)–related autoantibody directed against a complex consisting of RuvBL1 and RuvBL2 (RuvBL1/2) and to assess its clinical correlations. Methods We first analyzed 316 consecutive pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ccfaf491a8e4b3d7914e2d2e597cb02c
https://doi.org/10.1002/acr.22163
https://doi.org/10.1002/acr.22163