Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Kana, Miyahara"'
Autor:
Kana Miyahara, Naoharu Takano, Yumiko Yamada, Hiromi Kazama, Mayumi Tokuhisa, Hirotsugu Hino, Koji Fujita, Edward Barroga, Masaki Hiramoto, Hiroshi Handa, Masahiko Kuroda, Takashi Ishikawa, Keisuke Miyazawa
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract BRCA1 is a well-studied tumor suppressor involved in the homologous repair of DNA damage, whereas PINK1, a mitochondrial serine/threonine kinase, is known to be involved in mitochondrial quality control. Genetic mutations of PINK1 and Parkin
Externí odkaz:
https://doaj.org/article/2b53b82c6ae5403ab382220048b0b353
Autor:
Yoichi Koyama, Kayo Adachi, Mio Yagi, Yoko Go, Kyoko Orimoto, Saori Kawai, Natsuki Uenaka, Miki Okazaki, Mariko Asaoka, Saeko Teraoka, Ai Ueda, Kana Miyahara, Takahiko Kawate, Hiroshi Kaise, Kimito Yamada, Takashi Ishikawa
Publikováno v:
Surgical Case Reports, Vol 7, Iss 1, Pp 1-5 (2021)
Abstract Background With the introduction of dose-dense therapy, the use of primary pegfilgrastim (PEG-G) has been increasing in breast cancer treatment. A rare side effect of PEG-G is aortitis. We describe a case of PEG-G-induced aortitis. Case pres
Externí odkaz:
https://doaj.org/article/0c8c84f71cb54c438690a26f5a5b4e0c
Autor:
Kayo Adachi, Fuyo Kimura, Hideto Takahashi, Hiroshi Kaise, Kimito Yamada, Ei Ueno, Takahiko Kawate, Kana Miyahara, Ai Ueda, Saeko Sato, Mariko Asaoka, Miki Okazaki, Natsuki Uenaka, Kyoko Orimoto, Rongrong Wu, Yoichi Koyama, Takashi Ishikawa
Publikováno v:
Clinical Breast Cancer. 23:265-271
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::258119c1198aa71ecade8e98adec47a7
https://doi.org/10.1016/j.clbc.2023.01.001
https://doi.org/10.1016/j.clbc.2023.01.001
Publikováno v:
Journal of Case Reports and Images in Oncology. 7:1-6
Introduction: Chemotherapy is the only systemic treatment option for triple-negative breast cancer (TNBC) patients, and is often used in combination with anthracycline and taxane. However, it was reported that many TNBCs show BRCA dysfunction, and ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8bc894551d2ed78a85cdb558c1bf727c
https://doi.org/10.5348/100089z10fk2021cr
https://doi.org/10.5348/100089z10fk2021cr
Autor:
Masako, Muguruma, Mariko, Asaoka, Saeko, Teraoka, Kana, Miyahara, Takahiko, Kawate, Takashi, Ishikawa
Publikováno v:
Anticancer Research. 42:4735-4742
We previously reported that the half maximal inhibitory concentration (ICWe investigated the expression levels of β-tubulin isoforms by real-time polymerase chain reaction and morphology of spheroid formation in the 13 TNBC cell lines cultured using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59854b995f79df0f42536b9963121435
https://doi.org/10.21873/anticanres.15978
https://doi.org/10.21873/anticanres.15978
Autor:
Kana Miyahara, Kazutaka Narui, Yukari Uemura, Akimitsu Yamada, Kazuhiro Araki, Fumie Fujisawa, Takahiro Nakayama, Takashi Ishikawa, Naruto Taira, Yuichiro Kikawa, Tomohiko Aihara, Hirofumi Mukai
Publikováno v:
World Journal of Oncology. 13:216-221
Combination therapy with cyclin-dependent kinase 4 and 6 (CDK4/6) inhibitors and hormonal therapy as the first-line and second-line treatments has already been shown to be effective in patients with hormone receptor-positive (HR+) human epidermal gro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76c2923e9cd1eee54225f3c76255a265
https://doi.org/10.14740/wjon1511
https://doi.org/10.14740/wjon1511
Autor:
Yusuke Nakamura, Soo Chin Lee, Ching-Wan Chan, Mikael Hartman, Ern Yu Tan, Arata Shimo, Koichiro Tsugawa, Daisuke Shimizu, Kazuhiro Shimada, Akimitsu Yamada, Shinichi Baba, Yasuaki Sagara, Ayami Matsukata, Mai Onomura, Hisamitsu Zaha, Minoru Okazaki, Fukino Satomi, Hiroaki Shima, Goro Kutomi, Yoshie Hasegawa, Hiroshi Matsumoto, Kana Miyahara, Takashi Ishikawa, Hiroyuki Takei, Tomoko Takamaru, Chie Watanabe, Takashi Kuwayama, Sadako Akashi-Tanaka, Seigo Nakamura, Hitoshi Zembutsu
Supplementary Figure S1. 　ER status in breast cancer tissues was associated with Ki-67 response after tamoxifen therapy. (A) Ki-67 response was lower in the tissues in which the proportion of ER-positive cells was less than 2/3 than in the tis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36cda7d9e05983c54069e73f82173ebc
https://doi.org/10.1158/1078-0432.22465632
https://doi.org/10.1158/1078-0432.22465632
Autor:
Yusuke Nakamura, Soo Chin Lee, Ching-Wan Chan, Mikael Hartman, Ern Yu Tan, Arata Shimo, Koichiro Tsugawa, Daisuke Shimizu, Kazuhiro Shimada, Akimitsu Yamada, Shinichi Baba, Yasuaki Sagara, Ayami Matsukata, Mai Onomura, Hisamitsu Zaha, Minoru Okazaki, Fukino Satomi, Hiroaki Shima, Goro Kutomi, Yoshie Hasegawa, Hiroshi Matsumoto, Kana Miyahara, Takashi Ishikawa, Hiroyuki Takei, Tomoko Takamaru, Chie Watanabe, Takashi Kuwayama, Sadako Akashi-Tanaka, Seigo Nakamura, Hitoshi Zembutsu
Supplementary Table S1 Association between all CYP2D6 genotype and ER status in pre-treatment tissue.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dbeb03daafb0aa3d97beff4ff255f1c
https://doi.org/10.1158/1078-0432.22465629
https://doi.org/10.1158/1078-0432.22465629
Autor:
Yusuke Nakamura, Soo Chin Lee, Ching-Wan Chan, Mikael Hartman, Ern Yu Tan, Arata Shimo, Koichiro Tsugawa, Daisuke Shimizu, Kazuhiro Shimada, Akimitsu Yamada, Shinichi Baba, Yasuaki Sagara, Ayami Matsukata, Mai Onomura, Hisamitsu Zaha, Minoru Okazaki, Fukino Satomi, Hiroaki Shima, Goro Kutomi, Yoshie Hasegawa, Hiroshi Matsumoto, Kana Miyahara, Takashi Ishikawa, Hiroyuki Takei, Tomoko Takamaru, Chie Watanabe, Takashi Kuwayama, Sadako Akashi-Tanaka, Seigo Nakamura, Hitoshi Zembutsu
Purpose: CYP2D6 is the key enzyme responsible for the generation of the potent active metabolite of tamoxifen, “endoxifen.” There are still controversial reports questioning the association between CYP2D6 genotype and tamoxifen efficacy. Hence, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71ce89ce8de2a1c253ff6b551d8c5a9d
https://doi.org/10.1158/1078-0432.c.6526092
https://doi.org/10.1158/1078-0432.c.6526092
Autor:
Miki Okazaki, Masako Muguruma, Takako Komiya, Kana Miyahara, Takahiko Kawate, Ai Ueda, Saeko Teraoka, Mariko Asaoka, Eiichi Sato, Hajime Matsumura, Takashi Ishikawa
Publikováno v:
Breast Cancer. 29:343-351
Capsular contracture is the most common complication with smooth-type silicone implants. We investigated the preventive effect of an active metabolite of tamoxifen, 4-hydroxytamoxifen (4-OH TAM), on capsular contracture.A silicone sheet was implanted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cd952210a3c34ad21adecf2548b3f37
https://doi.org/10.1007/s12282-021-01316-y
https://doi.org/10.1007/s12282-021-01316-y