Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Kan-Luk Cheung"'
Autor:
Jillian M. Birch, David Scott, Miles Evans, John L. Hungerford, Judith E. Kingston, B. Gibbons, Christine J. Harrison, S. P. Attard-Montalto, Kan Luk Cheung
Publikováno v:
Clinical Genetics. 47:311-317
Two children presenting with sporadic unilateral retinoblastoma and exhibiting a high degree of chromosome breakage were noted to have unusual facies, microcephaly and abnormal skin pigmentation. In the first child the pattern of both spontaneous and
Autor:
Fiona M. Ross, Gareth J. Morgan, Gianpaolo Dagrada, T Parker, C Rudduck, A Wechalekar, Rebecca K.M. Protheroe, E.D. Cabanas, A H Ibrahim, Mathew Nightingale, Kim Orchard, Christine J. Harrison, Nicholas C.P. Cross, Kan Luk Cheung, Laura Chiecchio
Publikováno v:
Leukemia. 20:1610-1617
In myeloma, the prognostic impact of different strategies used to detect chromosome 13 deletion (Delta13) remains controversial. To address this, we compared conventional cytogenetics and interphase fluorescence in situ hybridization (iFISH) in a lar
Autor:
M Martineau, Kan Luk Cheung, Brenda Gibson, Christine J. Harrison, Tim O B Eden, Sally E. Kinsey, Zoë J. Broadfield, Rachel L. Harris, G. Reza Jalali, Kerry E. Taylor, Hazel M. Robinson, Ian Hann, Frank Hill, Chris Mitchell, Anthony V. Moorman, Sue Richards
Publikováno v:
Blood. 102:2756-2762
High hyperdiploidy (HeH) (51 to 65 chromosomes) is found in one third of children with acute lymphoblastic leukemia and is associated with a good prognosis. Cytogenetic features may further refine this prognosis and identify patients with a poor outc
Autor:
Christine J. Harrison, Patricia C. M. O’Brien, Tina Butler, Kan-Luk Cheung, Malcolm A. Ferguson-Smith, Brian J. Hennessy, H. Grant Prentice, Fengtang Yang
Publikováno v:
Genes, Chromosomes and Cancer. 30:15-24
Cross-species color banding is a multiple-color fluorescence in situ hybridization (FISH) technique using probes developed from other animal species. Hybridization to human metaphases produces color banding patterns specific for each homologous chrom
Autor:
B. Gibbons, Lyndal Kearney, Kan Luk Cheung, Simon Monard, Bryan D. Young, Debra M. Lillington, T. Andrew Lister
Publikováno v:
Genes, Chromosomes and Cancer. 10:244-249
Eight patients with myeloid disorders characterised by a karyotype including apparent monosomy or partial monosomy 7, in the presence of a ring or marker chromosome, were investigated by fluorescence in situ hybridisation (FISH) with a chromosome 7 c
Autor:
Kim Orchard, Kan Luk Cheung, Gianpaolo Dagrada, Rebecca K.M. Protheroe, Christine J. Harrison, Nicholas C.P. Cross, Laura Chiecchio, Helen E. White, David M. Stockley, Mark R. Towsend, Fiona M. Ross
Publikováno v:
Genes, chromosomescancer. 48(7)
Plasma cell leukemia (PCL) is a rare form of monoclonal gammopathy, which can originate de novo or evolve from multiple myeloma (MM) as a terminal leukemic phase. Previous cytogenetic studies of PCL have reported the presence of complex karyotypes wi
Autor:
M Martineau, John S. Lilleyman, Sue Richards, Kan Luk Cheung, Fiona M. Ross, Christine J. Harrison, Zoë J. Broadfield, Anthony V. Moorman, G. Reza Jalali, Kerry E. Barber, Hazel M. Robinson
Publikováno v:
Genes, chromosomes and cancer. 43(1)
This study was undertaken in order to compare the interphase and metaphase cytogenetics of 28 patients with ETV6/RUNX1 positive acute lymphoblastic leukemia, at diagnosis and relapse. The median time to relapse was 26 months. The significant fusion p
Autor:
Kan Luk Cheung, Zoë J. Broadfield, Kerry E. Barber, G R Jalali, Anthony V. Moorman, Hazel M. Robinson, Jonathan C. Strefford, Rachel L. Harris, Christine J. Harrison, M Martineau
Publikováno v:
Leukemia. 19(4)
Deletions from the derivative chromosome 9, der(9), of the translocation, t(9;22)(q34;q11), at the site of the ABL/BCR fusion gene, have been demonstrated by fluorescence in situ hybridisation (FISH), in both Philadelphia chromosome (Ph)-positive chr
Autor:
Jonathan C. Strefford, Monica Stewart, Hazel M. Robinson, S Rutherford, Kerry E. Barber, G R Jalali, Christine J. Harrison, T D Allen, Kan Luk Cheung, Rachel L. Harris, Zoë J. Broadfield, M Martineau, Anthony V. Moorman, Ewan R. Cameron, Louise Harewood
Publikováno v:
Leukemia. 18(6)
Autor:
Hazel M. Robinson, G. Reza Jalali, Kerry E. Taylor, Kan Luk Cheung, Anthony V. Moorman, Christine J. Harrison
Publikováno v:
Genes, chromosomescancer. 39(1)
The recurrent t(14;19)(q32;q13) translocation associated with chronic B-cell lymphoproliferative disorders, such as atypical chronic lymphocytic leukemia, results in the juxtaposition of the IGH@ and BCL3 genes and subsequent overexpression of BCL3.