Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Kan Ito"'
Autor:
Tomohisa Sakai, Yoshihiro Nishida, Kan Ito, Kunihiro Ikuta, Hiroshi Urakawa, Hiroshi Koike, Shiro Imagama
Publikováno v:
Cancer Medicine, Vol 12, Iss 5, Pp 5245-5254 (2023)
Abstract Background The treatment of choice for desmoid‐type fibromatosis (DF) has been changed to active surveillance (AS). However, few studies have reported clinical outcomes of AS modality in Asian countries. This study aimed to clarify the sig
Externí odkaz:
https://doaj.org/article/d9bae89dae3540f38028861057163130
Autor:
Kan Ito, Yoshihiro Nishida, Shunsuke Hamada, Koki Shimizu, Tomohisa Sakai, Bisei Ohkawara, Benjamin A. Alman, Atsushi Enomoto, Kunihiro Ikuta, Hiroshi Koike, Jiarui Zhang, Kinji Ohno, Shiro Imagama
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Anticancer drugs and molecular targeted therapies are used for refractory desmoid-type fibromatosis (DF), but occasionally cause severe side effects. The purpose of this study was to identify an effective drug with fewer side effects against
Externí odkaz:
https://doaj.org/article/b103c9d9c681484a9d7276bc4c0c3415
Autor:
Jiarui Zhang, Yoshihiro Nishida, Hiroshi Koike, Lisheng Zhuo, Kan Ito, Kunihiro Ikuta, Tomohisa Sakai, Shiro Imagama
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 15, p 12422 (2023)
This study aimed to clarify the effects of ipriflavone, which effectively reduces KIAA1199 activity, on osteoarthritis (OA) development and progression in an in vivo OA mouse model. The OA model mice were divided into the ipriflavone (200 mg/kg/day)
Externí odkaz:
https://doaj.org/article/b578f9ca63cc4ee99b30cb0962c1dd71
Autor:
Yoshihiro Nishida, Shunsuke Hamada, Tomohisa Sakai, Kan Ito, Kunihiro Ikuta, Hiroshi Urakawa, Hiroshi Koike, Shiro Imagama
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract The mainstay of treatment for desmoid has been shifted to active surveillance (AS). However, surgery is still being performed on abdominal wall desmoid with a wide surgical margin. The purposes of this study are to clarify the treatment resu
Externí odkaz:
https://doaj.org/article/bb8cc918e08145e3b56e847b29781fce
Autor:
Kan Ito, Yoshihiro Nishida, Kunihiro Ikuta, Hiroshi Urakawa, Hiroshi Koike, Tomohisa Sakai, Jiarui Zhang, Yoshie Shimoyama, Shiro Imagama
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 16, Iss 1, Pp 1-10 (2021)
Abstract Background Hyaluronan (HA) has been shown to play important roles in the growth, invasion, and metastasis of malignant tumors. KIAA1199, which has potent HA-degrading activity, has been reported to be expressed in various malignancies and as
Externí odkaz:
https://doaj.org/article/52816bdd664c4c28b1581a2cfa07ee2c
Autor:
Kunihiro Ikuta, Yoshihiro Nishida, Tomohisa Sakai, Hiroshi Koike, Kan Ito, Hiroshi Urakawa, Shiro Imagama
Publikováno v:
Journal of Clinical Medicine, Vol 11, Iss 19, p 5695 (2022)
Background: Nodular plexiform neurofibromas in individuals with neurofibromatosis type 1 often cause significant symptoms and are treated with surgical excision despite the potential risk of complications. This study aimed to clarify the surgical out
Externí odkaz:
https://doaj.org/article/32a0ccaf77f74ca19e536542c6754a69
Autor:
Jiarui Zhang, Yoshihiro Nishida, Hiroshi Koike, Kan Ito, Lisheng Zhuo, Kazuki Nishida, Koji Kimata, Kunihiro Ikuta, Tomohisa Sakai, Hiroshi Urakawa, Taisuke Seki, Shiro Imagama
Publikováno v:
Journal of Orthopaedic Research. 41:307-315
Hyaluronan (HA) plays crucial roles in the maintenance of high-quality cartilage extracellular matrix. Several studies have reported the HA in synovial fluid in patients with osteoarthritis (OA), but few have described the changes of HA in articular
Autor:
Tomohisa Sakai, Yoshihiro Nishida, Kan Ito, Kunihiro Ikuta, Hiroshi Urakawa, Hiroshi Koike, Shiro Imagama
Publikováno v:
Cancer medicineREFERENCES.
The treatment of choice for desmoid-type fibromatosis (DF) has been changed to active surveillance (AS). However, few studies have reported clinical outcomes of AS modality in Asian countries. This study aimed to clarify the significance of AS as a D
Autor:
Yoshihiro Nishida, Yosuke Yamada, Masahiro Hirata, Hironori Haga, Akio Sakamoto, Shuichi Matsuda, Kan Ito, Takashi Noguchi
Publikováno v:
Pathology International. 71(6):392-399
Desmoid-type fibromatosis (DF) is a locally aggressive but non-metastatic (myo)fibroblastic neoplasm. A hallmark of the tumor is nuclear positivity for beta-catenin in immunohistochemistry due mostly to CTNNB1 mutations. However, a recent study has r
Autor:
Kunihiro Ikuta, Yoshihiro Nishida, Hiroshi Koike, Hiroshi Urakawa, Shiro Imagama, Kan Ito, Tomohisa Sakai, Shinji Ito
Publikováno v:
Cancer Science
The purposes of this study were to re‐confirm the usefulness of PET/CT in the differentiation of benignity/malignancy of neurogenic tumors in NF1 patients, and to analyze the natural course of plexiform neurofibroma (pNF) and clarify whether PET/CT