Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Kan Chantranuvatana"'
Autor:
Shanshan He, Ruchir Bhatt, Carl Brown, Emily A. Brown, Derek L. Buhr, Kan Chantranuvatana, Patrick Danaher, Dwayne Dunaway, Ryan G. Garrison, Gary Geiss, Mark T. Gregory, Margaret L. Hoang, Rustem Khafizov, Emily E. Killingbeck, Dae Kim, Tae Kyung Kim, Youngmi Kim, Andrew Klock, Mithra Korukonda, Alecksandr Kutchma, Zachary R. Lewis, Yan Liang, Jeffrey S. Nelson, Giang T. Ong, Evan P. Perillo, Joseph C. Phan, Tien Phan-Everson, Erin Piazza, Tushar Rane, Zachary Reitz, Michael Rhodes, Alyssa Rosenbloom, David Ross, Hiromi Sato, Aster W. Wardhani, Corey A. Williams-Wietzikoski, Lidan Wu, Joseph M. Beechem
Publikováno v:
Nature Biotechnology. 40:1794-1806
Resolving the spatial distribution of RNA and protein in tissues at subcellular resolution is a challenge in the field of spatial biology. We describe spatial molecular imaging, a system that measures RNAs and proteins in intact biological samples at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ee5f3689cfbb16a84e4f40fd251566f
https://doi.org/10.1038/s41587-022-01483-z
https://doi.org/10.1038/s41587-022-01483-z
Autor:
Tien Phan-Everson, Jianji Chen, Zachary Lewis, Gary Geiss, Yan Liang, Emily Brown, Liuliu Pan, Stefan Phelan, Charlie Glaser, Mithra Korukonda, Carl Brown, Dwayne Dunaway, Joseph Phan, Alyssa Rosenbloom, Brian Filanoski, Rhonda Meredith, Kan Chantranuvatana, Brian Birditt, Giang Ong, Hye Son Yi, Erin Piazza, Jason Reeves, Subham Basu, Christine Kang, Vik Devgan, Edward Zhao, Michael Rhodes, Joseph Beechem
Publikováno v:
Regular and Young Investigator Award Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aefd8878f26633f9a02079d8547b3a1a
https://doi.org/10.1136/jitc-2022-sitc2022.0147
https://doi.org/10.1136/jitc-2022-sitc2022.0147
Autor:
Zachary R. Lewis, Brian Birditt, Emily Brown, Kan Chantranuvatana, Brian Filanoski, Chris Corless, Tiên Phan-Everson, Gary Geiss, Tyler Hether, Evie Hobbs, Brett Johnson, Taylor Kelley, Charles Lopez, Rhonda Meredith, Anastasiya Olson, Giang Ong, Mithra Korukonda, Erin Piazza, Jason Reeves, Alyssa Rosenbloom, Kiara Siex, Hye Son Yi, Edward Zhao, Joseph M. Beechem, Gordon Mills
Publikováno v:
Cancer Research. 83:5641-5641
The power of spatial biology lies in the integration of multiple scales of information from subcellular to tissue scale. Until recently, spatial analysis of protein biomarkers in tissues was limited to a few markers at a time using traditional IHC co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5526266edf25a0f60c7099f849e2615c
https://doi.org/10.1158/1538-7445.am2023-5641
https://doi.org/10.1158/1538-7445.am2023-5641
Autor:
Tien Phan-Everson, Zachary Lewis, Giang Ong, Yan Liang, Emily Brown, Liuliu Pan, Aster Wardhani, Mithra Korukonda, Carl Brown, Dwayne Dunaway, Edward Zhao, Dan McGuire, Sangsoon Woo, Alyssa Rosenbloom, Brian Filanoski, Rhonda Meredith, Kan Chantranuvatana, Brian Birditt, Hye Son Yi, Erin Piazza, Jason Reeves, John Lyssand, Vik Devgan, Michael Rhodes, Gary Geiss, Joseph Beechem
Publikováno v:
Cancer Research. 83:4617-4617
Detecting and analyzing large numbers of proteins using whole-slide imaging is critical for a comprehensive picture of immune response to cancer. Many existing approaches for high-plex proteomics face issues around simplicity, speed, scalability, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::382f14385cec3c84bd43e11cd2ea4a3a
https://doi.org/10.1158/1538-7445.am2023-4617
https://doi.org/10.1158/1538-7445.am2023-4617
Autor:
Shanshan He, Ruchir Bhatt, Carl Brown, Emily A. Brown, Derek L. Buhr, Kan Chantranuvatana, Patrick Danaher, Dwayne Dunaway, Ryan G. Garrison, Gary Geiss, Mark T. Gregory, Margaret L. Hoang, Rustem Khafizov, Emily E. Killingbeck, Dae Kim, Tae Kyung Kim, Youngmi Kim, Andrew Klock, Mithra Korukonda, Alecksandr Kutchma, Zachary R. Lewis, Yan Liang, Jeffrey S. Nelson, Giang T. Ong, Evan P. Perillo, Joseph C. Phan, Tien Phan-Everson, Erin Piazza, Tushar Rane, Zachary Reitz, Michael Rhodes, Alyssa Rosenbloom, David Ross, Hiromi Sato, Aster W. Wardhani, Corey A. Williams-Wietzikoski, Lidan Wu, Joseph M. Beechem
The Spatial Molecular Imaging platform (CosMxTM SMI, NanoString Technologies, Seattle, WA) utilizes high-plex in-situ imaging chemistry for both RNA and protein detection. This automated instrument provides 1000’s of plex, at high sensitivity (1 to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c63eed1be671eeea583cad189d792534
https://doi.org/10.1101/2021.11.03.467020
https://doi.org/10.1101/2021.11.03.467020
Autor:
Zachary R. Lewis, Tien Phan-Everson, Gary Geiss, Mithra Korukonda, Ruchir Bhatt, Carl Brown, Dwayne Dunaway, Joseph Phan, Alyssa Rosenbloom, Brian Filanoski, Rhonda Meredith, Kan Chantranuvatana, Yan Liang, Emily Brown, Brian Birditt, Giang Ong, Hye Son Yi, Erin Piazza, Vikram Devgan, Nicole Ortogero, Patrick Danaher, Sarah Warren, Michael Rhodes, Joseph Beechem
Publikováno v:
Cancer Research. 82:3878-3878
The spatial interactions between the immune system and tumor cells greatly influence antitumoral immunity. Characterization of immune cell composition and infiltration within the tumor niche informs prognosis, drug delivery efficiency, and therapeuti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43cbdb013ffc80b0808010492ace2540
https://doi.org/10.1158/1538-7445.am2022-3878
https://doi.org/10.1158/1538-7445.am2022-3878
Autor:
Hai T. Tran, Jefferson D. Knight, Kan Chantranuvatana, Matthew D. Coffman, Joseph K. Vasquez, Daniel T. Giardina
Publikováno v:
Biophysical Journal. 110(3)
Synaptotagmin 1 (Syt1), a Ca2+ sensor involved in exocytosis in pre-synaptic neurons, contains a characteristic tandem C2 sequence (C2AB) which inserts into anionic membranes in the presence of Ca2+. Previous studies have shown that the C2AB fragment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afae9dfe2f19148243982a0af4edcf9a
Autor:
Daniel T. Giardina, Kan Chantranuvatana, Matthew D. Coffman, Jefferson D. Knight, Joseph K. Vasquez
Publikováno v:
Biochemistry
The synaptotagmin (Syt) family of proteins contains tandem C2 domains, C2A and C2B, which bind membranes in the presence of Ca(2+) to trigger vesicle fusion during exocytosis. Despite recent progress, the role and extent of interdomain interactions b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf49da2f8d27ac37fa76b48d243ef972
https://pubmed.ncbi.nlm.nih.gov/25437758
https://pubmed.ncbi.nlm.nih.gov/25437758
Autor:
Joseph J. Falke, Devin S. Brandt, Beatriz Salazar, Kan Chantranuvatana, J. Ryan Osterberg, Matthew D. Coffman, Jefferson D. Knight
Publikováno v:
Biophysical Journal. 104:537a
Synaptotagmin (Syt) proteins serve as Ca2+ sensitive triggers in many exocytotic pathways, with the seventeen different human isoforms active in various cell types. Syt proteins contain two C2 domains, C2A and C2B, which bind membranes in response to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d40d383c6d08fd96b0a0ec3f7b4f1be
https://doi.org/10.1016/j.bpj.2012.11.2972
https://doi.org/10.1016/j.bpj.2012.11.2972
Publikováno v:
Biophysical Journal. (2):311a-312a
The synaptotagmin (Syt) family of proteins contains tandem C2 domains, C2A and C2B, which bind membranes in the presence of Ca2+. The precise mechanism by which Syt participates in membrane fusion events is not completely understood, and the role of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0399e1251f84a74fe8933177cd54d659