Zobrazeno 1 - 10
of 442
pro vyhledávání: '"Kan, V."'
Autor:
Kan, V. (Valerii)
Parkinson’s disease (PD) is a second most common neurological disorder that affects up to 10 million people worldwide. However, in spite of this vast number of patients, there is still no universal and applicable for everyone type of treatment. The
Externí odkaz:
http://urn.fi/URN:NBN:fi:oulu-201806022431
Akademický článek
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Autor:
Vatsalya Vatsalya, Maiying Kong, Luis M Marsano, Zimple Kurlawala, Kan V Chandras, Melanie L Schwandt, Vijay A Ramchandani, Craig J McClain
Publikováno v:
Substance Abuse: Research and Treatment, Vol 14 (2020)
Background: Shared etiological pathways of dopamine and serotonin neurotransmission play a central role in heavy alcohol intake and exacerbation in the symptoms of depression. We investigated the treatment efficacy of Quetiapine fumarate extended rel
Externí odkaz:
https://doaj.org/article/e00370c696e94becac38ec234b31b03a
Autor:
Joanna J. Phillips, William A. Weiss, Monika E. Hegi, Albert Lai, William H. Yong, Theodore P. Nicolaides, C. David James, Joseph T.C. Shieh, Mitchel S. Berger, Andrew W. Bollen, Michael Prados, Linda M. Liau, Timothy F. Cloughesy, Erin F. Simonds, Kan V. Lu, Henry Gong, Anupam Kumar, Katharine Y. Chen, Jane R. Engler, Olle R. Lindberg, Andrew McKinney
Supplementary Figure S1 shows increased invasion is specific to EGFR inhibition, increased ALDH1A1 expression is not specific to erlotinib but also occurs with AG1478 and lapatinib, and EGFR inhibition increases expression of several genes implicated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00141c8ad56ed4fbd4e04e650a02b942
https://doi.org/10.1158/1535-7163.22506199
https://doi.org/10.1158/1535-7163.22506199
Autor:
Joanna J. Phillips, William A. Weiss, Monika E. Hegi, Albert Lai, William H. Yong, Theodore P. Nicolaides, C. David James, Joseph T.C. Shieh, Mitchel S. Berger, Andrew W. Bollen, Michael Prados, Linda M. Liau, Timothy F. Cloughesy, Erin F. Simonds, Kan V. Lu, Henry Gong, Anupam Kumar, Katharine Y. Chen, Jane R. Engler, Olle R. Lindberg, Andrew McKinney
Amplification of the epidermal growth factor receptor gene (EGFR) represents one of the most commonly observed genetic lesions in glioblastoma (GBM); however, therapies targeting this signaling pathway have failed clinically. Here, using human tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ab7e13d5ba0dbfc1f50b929a8ae3a3d
https://doi.org/10.1158/1535-7163.c.6538321.v1
https://doi.org/10.1158/1535-7163.c.6538321.v1
Autor:
Paul S. Mischel, Charles L. Sawyers, Timothy F. Cloughesy, Ingo K. Mellinghoff, Webster K. Cavenee, Gregory M. Shackleford, Igor Vivanco, Ederlyn Q. Dia, Shaojun Zhu, Kan V. Lu, Maria Y. Wang
The epidermal growth factor receptor (EGFR) is commonly amplified, overexpressed, and mutated in glioblastoma, making it a compelling molecular target for therapy. We have recently shown that coexpression of EGFRvIII and PTEN protein by glioblastoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d5c233e960ac5ff0bc859d5d77d3cae
https://doi.org/10.1158/0008-5472.c.6494484.v1
https://doi.org/10.1158/0008-5472.c.6494484.v1
Autor:
Paul S. Mischel, Terrance G. Johns, Webster K. Cavenee, C. David James, Frank B. Furnari, Thomas Graeber, Gabriele Bergers, Stanley F. Nelson, Timothy F. Cloughesy, Roberto Weinmann, Francis Y. Lee, Arnab Chakravari, David Seligson, Joseph A. Loo, Yongmin Xie, Jeremy S. Caldwell, Zugen Chen, Yohan Lee, Isaac Oderberg, Seema B. Plaisier, Eduard B. Dinca, Julie Dang, David Ahkavan, Shawn Sarkaria, Tiffany T. Huang, Anna Cvrljevic, Shaojun Zhu, Kan V. Lu
Supplementary Methods and Materials from Fyn and Src Are Effectors of Oncogenic Epidermal Growth Factor Receptor Signaling in Glioblastoma Patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::703945b51323dac67390a09527661f97
https://doi.org/10.1158/0008-5472.22377681
https://doi.org/10.1158/0008-5472.22377681
Autor:
C. David James, Mitchel S. Berger, Scott R. VandenBerg, Daphne A. Haas-Kogan, Michael D. Prados, Russell O. Pieper, Jann N. Sarkaria, Kan V. Lu, Eduard B. Dinca
Supplementary Figures 1-4 from p53 Small-Molecule Inhibitor Enhances Temozolomide Cytotoxic Activity against Intracranial Glioblastoma Xenografts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd0f79049b378225d9dc93e170892707
https://doi.org/10.1158/0008-5472.22377242
https://doi.org/10.1158/0008-5472.22377242
Autor:
Paul S. Mischel, Charles L. Sawyers, Timothy F. Cloughesy, Ingo K. Mellinghoff, Webster K. Cavenee, Gregory M. Shackleford, Igor Vivanco, Ederlyn Q. Dia, Shaojun Zhu, Kan V. Lu, Maria Y. Wang
Supplementary Table 1 from Mammalian Target of Rapamycin Inhibition Promotes Response to Epidermal Growth Factor Receptor Kinase Inhibitors in PTEN-Deficient and PTEN-Intact Glioblastoma Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45296f868a8d89b030a992977f0abf49
https://doi.org/10.1158/0008-5472.22365003
https://doi.org/10.1158/0008-5472.22365003
Autor:
Paul S. Mischel, Terrance G. Johns, Webster K. Cavenee, C. David James, Frank B. Furnari, Thomas Graeber, Gabriele Bergers, Stanley F. Nelson, Timothy F. Cloughesy, Roberto Weinmann, Francis Y. Lee, Arnab Chakravari, David Seligson, Joseph A. Loo, Yongmin Xie, Jeremy S. Caldwell, Zugen Chen, Yohan Lee, Isaac Oderberg, Seema B. Plaisier, Eduard B. Dinca, Julie Dang, David Ahkavan, Shawn Sarkaria, Tiffany T. Huang, Anna Cvrljevic, Shaojun Zhu, Kan V. Lu
Supplementary Figures 1-6 from Fyn and Src Are Effectors of Oncogenic Epidermal Growth Factor Receptor Signaling in Glioblastoma Patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb6bf66d3709417bb53917c554b6fde7
https://doi.org/10.1158/0008-5472.22377684
https://doi.org/10.1158/0008-5472.22377684