Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Kan, Uchiyama"'
Autor:
Machi Suka, Hiroyuki Yanagisawa, Nobuhiro Sato, Shigetaka Shimodaira, Masayuki Saruta, Shigeo Koido, Junichi Taguchi, Masamori Shimabuku, Shin Kan, Tuuse Bito, Takeyuki Misawa, Zensho Ito, Kan Uchiyama, Shintaro Tsukinaga, Toshifumi Ohkusa, Haruo Sugiyama
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 10 (2024)
Background We aimed to develop a chemoimmunotherapy regimen consisting of a novel Wilms’ tumor 1 (WT1) peptide-pulsed dendritic cell (WT1-DC) vaccine and multiagent chemotherapy and to investigate the safety, clinical outcomes, and WT1-specific imm
Externí odkaz:
https://doaj.org/article/3756c5f4da2747fd83b90f8049ea096a
Publikováno v:
DEN Open, Vol 4, Iss 1, Pp n/a-n/a (2024)
Abstract Objectives Segmental colitis associated with diverticulosis (SCAD) has close endoscopic and pathological similarities to ulcerative colitis (UC) and Crohn's disease. Clinical data on SCAD are limited in Japan. We examined the endoscopic and
Externí odkaz:
https://doaj.org/article/2340ae387847400ca512bf995916d51c
Autor:
Shizuka Suzuki, Kan Uchiyama, Yutaro Motoi, Yuuki Yoshii, Yukari Inoue, Takahiro Kubota, Shunichi Odahara, Yuichiro Ohtaki, Shinichiro Takami, Zensho Ito, Nobuhiro Sato, Toshifumi Ohkusa, Shigeo Koido, Masayuki Saruta
Publikováno v:
BMC Gastroenterology, Vol 23, Iss 1, Pp 1-11 (2023)
Abstract Background Thiopurines continue to play an important role in the treatment of inflammatory bowel disease (IBD). It is well known that thiopurines can cause several adverse reactions. Especially, hematopoietic toxicity may lead to severe agra
Externí odkaz:
https://doaj.org/article/5ef338f38413497daa6f52c09275bbff
Autor:
Shigeo Koido, Sankichi Horiuchi, Shin Kan, Tsuuse Bito, Zensho Ito, Kan Uchiyama, Masayuki Saruta, Nobuhiro Sato, Toshifumi Ohkusa
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Fusobacteria have been suspected to be pathobionts of colon cancer and inflammatory bowel disease. However, the immunomodulatory properties that affect these inflammatory reactions in dendritic cells (DCs) under anaerobic and aerobic conditi
Externí odkaz:
https://doaj.org/article/6598f3a5b34f4d25930735ece44eb223
Autor:
Sachie Kiryu, Zensho Ito, Machi Suka, Tsuuse Bito, Shin Kan, Kan Uchiyama, Masayuki Saruta, Taigo Hata, Yuki Takano, Shuichi Fujioka, Takeyuki Misawa, Takashi Yamauchi, Hiroyuki Yanagisawa, Nobuhiro Sato, Toshifumi Ohkusa, Haruo Sugiyama, Shigeo Koido
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-13 (2021)
Abstract Background Both activated tumor-infiltrating lymphocytes (TILs) and immune-suppressive cells, such as regulatory T cells (Tregs), in the tumor microenvironment (TME) play an important role in the prognosis of patients with pancreatic ductal
Externí odkaz:
https://doaj.org/article/8336055c81c24d62a8789f312e8859d7
Autor:
Yuichiro Ohtaki, Kan Uchiyama, Hirotaka Kamiya, Eri Moriizumi, Moe Yamada, Yuma Aoki, Toshimune Watanabe, Sachie Kiryu, Shizuka Suzuki, Yoshihiro Matsumoto, Zensho Ito, Toshifumi Ohkusa, Shigeo Koido, Masayuki Saruta
Publikováno v:
BMC Gastroenterology, Vol 23, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/d0a770709bd44b77bbdd1f31ca562dd0
Autor:
Yuriko Nishikawa, Nobuhiro Sato, Shintaro Tsukinaga, Kan Uchiyama, Shigeo Koido, Dai Ishikawa, Toshifumi Ohkusa
Publikováno v:
Therapeutic Advances in Chronic Disease, Vol 12 (2021)
Aims: An antibiotic combination of amoxicillin, tetracycline and metronidazole (ATM) is effective for ulcerative colitis (UC), but this regimen is discontinued in some cases due to adverse events. This study aimed to assess a revised combination, nam
Externí odkaz:
https://doaj.org/article/2b9c999b85f74e5ca312fd364737d5b8
Autor:
Yuichiro, Ohtaki1 (AUTHOR) yuu1ro.1985@jikei.ac.jp, Kan, Uchiyama1 (AUTHOR) uchikan@jikei.ac.jp, Hirotaka, Kamiya1 (AUTHOR), Eri, Moriizumi1 (AUTHOR), Moe, Yamada1 (AUTHOR), Yuma, Aoki1 (AUTHOR), Toshimune, Watanabe1 (AUTHOR), Sachie, Kiryu1 (AUTHOR), Sizuka, Suzuki1 (AUTHOR), Yoshihiro, Matsumoto1 (AUTHOR), Zensho, Ito1 (AUTHOR), Toshifumi, Ohkusa2 (AUTHOR), Shigeo, Koido1 (AUTHOR), Masayuki, Saruta3 (AUTHOR)
Publikováno v:
BMC Gastroenterology. 8/18/2022, Vol. 22 Issue 1, p1-7. 7p.
Autor:
Kan Uchiyama, Shinichiro Takami, Hideo Suzuki, Kiyotaka Umeki, Satoshi Mochizuki, Nobushige Kakinoki, Junichi Iwamoto, Yoko Hoshino, Jun Omori, Shunji Fujimori, Akinori Yanaka, Yuji Mizokami, Toshifumi Ohkusa
Publikováno v:
PLoS ONE, Vol 15, Iss 11, p e0241337 (2020)
IntroductionIndigo naturalis (IN) is a blue pigment extracted from Assam indigo and other plants and has been confirmed to be highly effective for ulcerative colitis (UC) treatment in several clinical studies.ObjectiveWe conducted a multicenter doubl
Externí odkaz:
https://doaj.org/article/886959c6899448fa9541f613eb55d9d1
Autor:
Keisuke Saito, Shigeo Koido, Toshitaka Odamaki, Mikio Kajihara, Kumiko Kato, Sankichi Horiuchi, Sei Adachi, Hiroshi Arakawa, Sayumi Yoshida, Takafumi Akasu, Zensho Ito, Kan Uchiyama, Masayuki Saruta, Jin-Zhong Xiao, Nobuhiro Sato, Toshifumi Ohkusa
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0212406 (2019)
Recent studies have suggested an association between certain members of the Fusobacterium genus, especially F. nucleatum, and the progression of advanced colorectal carcinoma (CRC). We assessed such an association of the gut microbiota in Japanese pa
Externí odkaz:
https://doaj.org/article/f8bc3ed2f04643e8b15e803d23466d52