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Akademický článek

Gene expression of nuclear factor of activated T-cells in children with bicuspid aortic valve

Autor: Kamenshchyk А.V., Kamyshny A.М., Ivanko О.G.

Publikováno v: Medičnì Perspektivi, Vol 21, Iss 3, Pp 29-33 (2016)

The genes of nuclear factor of activated T-cells (NFATC) play a key role both in heart valves formation and immune response. The genes belong to transcriptional factors and lead to myocardial hypertrophy in postnatal period that is confirmed by exper

Externí odkaz: https://doaj.org/article/5425cfab6e2b480d95fa32732345ac95

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Akademický článek

Features of immune metabolism of lymphocytes in pancreatic lymph nodes during experimental steptozotocin-induced diabetes mellitus and after introduction of metformin

Autor: Putilin D.A., Kamyshny A.M.

Publikováno v: Морфологія, Vol 10, Iss 2, Pp 61-68 (2016)

Background. Metabolic changes in terms of developing diabetes, especially hyperglycemia, can directly affect immune metabolism of lymphocytes. Objective: The aim was to find out the level of mRNA gene expression of Glut1, mTOR and AMPK1α in pancreat

Externí odkaz: https://doaj.org/article/0fc63c8c9a9148cc81cf0112a3c7c91c

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Akademický článek

[The influence of experimental gestational diabetes on expres-sion of Aire mRNA and character of differentiation of Foxp3+ - cells in mesenteric lymph nodes in the offspring]

Autor: Kamyshny A.M., Prozorova T.M., Kamyshna V.A.

Publikováno v: Морфологія, Vol 9, Iss 2, Pp 29-35 (2015)

Background. Formation of immunological tolerance to self-antigens is an important mechanism that prevents development of the autoimmune diseases. Objective. With the help of molecular genetic and immunofluorescence techniques to investigate the effec

Externí odkaz: https://doaj.org/article/58c7901fa9584974ac1c1476db22d62f

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Akademický článek

Influense of the effect of experimental diabetes mellitus on the protein expression of apoptotic regulators Bcl-2 and p53 in the lymphoid follicles of the spleen

Autor: Grinevich I., Kamyshny A.

Publikováno v: Морфологія, Vol 4, Iss 4, Pp 19-23 (2010)

The problem of investigation of molecular mechanisms of apoptosis and its role in autoimmune disease, includingdiabetes mellitus, became one of the most difficult and actual among the medical sciences last years. Under the experimentthe effect of exp

Externí odkaz: https://doaj.org/article/f3268ec2fc3f4bac870191a9a00fbaea

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Akademický článek

Peculiarities of protein р53 expression in rat thymus with experimental diabetes mellitus

Autor: Kamyshny A.M.

Publikováno v: Морфологія, Vol 3, Iss 1, Pp 38-43 (2009)

Peculiarities of protein р53 expression in rat thymus with experimental diabetes mellitus were investigated and discussed in experimental work. Investigations were carried out on 28 male rats Vistar line 5-6 months of age. Experimental diabetes mell

Externí odkaz: https://doaj.org/article/ae2b74f9b17d4e0a8fe4218927540232

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