Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Kamyar Hadian"'
Autor:
Juliane Tschuck, Vidya Padmanabhan Nair, Ana Galhoz, Carole Zaratiegui, Hin-Man Tai, Gabriele Ciceri, Ina Rothenaigner, Jason Tchieu, Brent R. Stockwell, Lorenz Studer, Daphne S. Cabianca, Michael P. Menden, Michelle Vincendeau, Kamyar Hadian
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract The development of functional neurons is a complex orchestration of multiple signaling pathways controlling cell proliferation and differentiation. Because the balance of antioxidants is important for neuronal survival and development, we hy
Externí odkaz:
https://doaj.org/article/444c8caf5d9e4924ae0ce2d1e59fd94d
Autor:
Dominik Schum, Franziska A. V. Elsen, Stuart Ruddell, Kenji Schorpp, Howard Junca, Mathias Müsken, Shu-Yu Chen, Michaela K. Fiedler, Thomas Pickl, Dietmar H. Pieper, Kamyar Hadian, Martin Zacharias, Stephan A. Sieber
Publikováno v:
JACS Au, Vol 4, Iss 8, Pp 3125-3134 (2024)
Externí odkaz:
https://doaj.org/article/65bd87ac39654709b229c1331699629c
Autor:
Juliane Tschuck, Lea Theilacker, Ina Rothenaigner, Stefanie A. I. Weiß, Banu Akdogan, Van Thanh Lam, Constanze Müller, Roman Graf, Stefanie Brandner, Christian Pütz, Tamara Rieder, Philippe Schmitt-Kopplin, Michelle Vincendeau, Hans Zischka, Kenji Schorpp, Kamyar Hadian
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Ferroptosis is a regulated cell death modality that occurs upon iron-dependent lipid peroxidation. Recent research has identified many regulators that induce or inhibit ferroptosis; yet, many regulatory processes and networks remain to be el
Externí odkaz:
https://doaj.org/article/c8879d0735a7477fa4fa2036c2269a28
Autor:
Kenji Schorpp, Alaa Bessadok, Aidin Biibosunov, Ina Rothenaigner, Stefanie Strasser, Tingying Peng, Kamyar Hadian
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-11 (2023)
Abstract Cell death, such as apoptosis and ferroptosis, play essential roles in the process of development, homeostasis, and pathogenesis of acute and chronic diseases. The increasing number of studies investigating cell death types in various diseas
Externí odkaz:
https://doaj.org/article/7296be3587b140738cb54ee5ac7603f8
Autor:
Valeria Napolitano, Charlotte A. Softley, Artur Blat, Vishal C. Kalel, Kenji Schorpp, Till Siebenmorgen, Kamyar Hadian, Ralf Erdmann, Michael Sattler, Grzegorz M. Popowicz, Grzegorz Dubin
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Trypanosomiases are life-threatening infections of humans and livestock, and novel effective therapeutic approaches are needed. Trypanosoma compartmentalize glycolysis into specialized organelles termed glycosomes. Most of the trypanosomal g
Externí odkaz:
https://doaj.org/article/ab883f4a01d442d8963c7e6b3aaf0f64
Autor:
Erwin Kupczyk, Kenji Schorpp, Kamyar Hadian, Sean Lin, Dimitrios Tziotis, Philippe Schmitt-Kopplin, Constanze Mueller
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 5453-5465 (2022)
Complex mixtures containing natural products are still an interesting source of novel drug candidates. High content screening (HCS) is a popular tool to screen for such. In particular, multiplexed HCS assays promise comprehensive bioactivity profiles
Externí odkaz:
https://doaj.org/article/4aa5cd7a00e84195a70b11e89e400f7e
Autor:
Xiaohua Yang, Maria Forstner, Christina K. Rapp, Ina Rothenaigner, Yang Li, Kamyar Hadian, Matthias Griese
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 9, p 8179 (2023)
Biallelic variants in ABCA3, the gene encoding the lipid transporter ATP-binding cassette subfamily A member 3 (ABCA3) that is predominantly expressed in alveolar type II cells, may cause interstitial lung diseases in children (chILD) and adults. Cur
Externí odkaz:
https://doaj.org/article/c41c818542fa4234ae4a6654f5d5cc20
Autor:
Pravin Kumar Ankush Jagtap, Tomáš Kubelka, Komal Soni, Cindy L. Will, Divita Garg, Claudia Sippel, Tobias G. Kapp, Harish Kumar Potukuchi, Kenji Schorpp, Kamyar Hadian, Horst Kessler, Reinhard Lührmann, Felix Hausch, Thorsten Bach, Michael Sattler
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
So far only a few compounds have been reported as splicing modulators. Here, the authors combine high-throughput screening, chemical synthesis, NMR, X-ray crystallography with functional studies and develop phenothiazines as inhibitors for the U2AF H
Externí odkaz:
https://doaj.org/article/816cddccf4d4425e993bdca998fb63bd
Autor:
Adrian Fischer, Tim Koopmans, Pushkar Ramesh, Simon Christ, Maximilian Strunz, Juliane Wannemacher, Michaela Aichler, Annette Feuchtinger, Axel Walch, Meshal Ansari, Fabian J. Theis, Kenji Schorpp, Kamyar Hadian, Philipp-Alexander Neumann, Herbert B. Schiller, Yuval Rinkevich
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Surgical adhesions are organ-joining bands of scar tissue that remain clinically untreatable. Here, the authors show that adhesions are formed through expansive mesothelial membrane bridges, and that blocking these with small molecules prevents forma
Externí odkaz:
https://doaj.org/article/14eab87dfd66492c8aa804c34480c9bf
Autor:
Vanessa A. N. Kraft, Carla T. Bezjian, Susanne Pfeiffer, Larissa Ringelstetter, Constanze Müller, Fereshteh Zandkarimi, Juliane Merl-Pham, Xuanwen Bao, Natasa Anastasov, Johanna Kössl, Stefanie Brandner, Jacob D. Daniels, Philippe Schmitt-Kopplin, Stefanie M. Hauck, Brent R. Stockwell, Kamyar Hadian, Joel A. Schick
Publikováno v:
ACS Central Science, Vol 6, Iss 1, Pp 41-53 (2019)
Externí odkaz:
https://doaj.org/article/6bf1885f0b7840f3938db0dc289ed06a