Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Kamran M Ahmed"'
Autor:
Polina Kosillo, Kamran M Ahmed, Erin E Aisenberg, Vasiliki Karalis, Bradley M Roberts, Stephanie J Cragg, Helen S Bateup
Publikováno v:
eLife, Vol 11 (2022)
The mTOR pathway is an essential regulator of cell growth and metabolism. Midbrain dopamine neurons are particularly sensitive to mTOR signaling status as activation or inhibition of mTOR alters their morphology and physiology. mTOR exists in two dis
Externí odkaz:
https://doaj.org/article/7be27d522af2436c8c1b4b13a65c9cf5
Autor:
Polina Kosillo, Natalie M. Doig, Kamran M. Ahmed, Alexander H.C.W. Agopyan-Miu, Corinna D. Wong, Lisa Conyers, Sarah Threlfell, Peter J. Magill, Helen S. Bateup
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-19 (2019)
Tuberous Sclerosis Complex (TSC) is a neurodevelopmental disorder caused by mutations in the TSC1 or TSC2 genes, which negatively regulate mTORC1 signalling. Here the authors selectively delete Tsc1 from dopamine neurons in mice and find impairments
Externí odkaz:
https://doaj.org/article/8f206497b65e4d93a92d89d476e37c28
Autor:
Kamran M Ahmed, Polina Kosillo, Erin E Aisenberg, Vasiliki Karalis, Bradley M Roberts, Stephanie J Cragg, Helen S Bateup
Publikováno v:
eLife. 11
The mTOR pathway is an essential regulator of cell growth and metabolism. Midbrain dopamine neurons are particularly sensitive to mTOR signaling status as activation or inhibition of mTOR alters their morphology and physiology. mTOR exists in two dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a743cdd1eaa7dca96fc461d128263179
https://doi.org/10.7554/elife.75398
https://doi.org/10.7554/elife.75398
The mTOR pathway is an essential regulator of cell growth and metabolism. Midbrain dopamine neurons are particularly sensitive to mTOR signaling status as activation or inhibition of mTOR alters their morphology and physiology. mTOR exists in two dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a682615d6951632290080b25bcd8c4a
https://doi.org/10.1101/2021.11.07.467637
https://doi.org/10.1101/2021.11.07.467637
Autor:
Natalie M. Doig, Peter J. Magill, Lisa Conyers, Alexander H.C.W. Agopyan-Miu, Polina Kosillo, Kamran M. Ahmed, Sarah Threlfell, Corinna D. Wong, Helen S. Bateup
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-19 (2019)
Nature Communications
Nature Communications, vol 10, iss 1
Nature communications, vol 10, iss 1
Nature Communications
Nature Communications, vol 10, iss 1
Nature communications, vol 10, iss 1
Tuberous Sclerosis Complex (TSC) is a neurodevelopmental disorder caused by mutations in TSC1 or TSC2, which encode proteins that negatively regulate mTOR complex 1 (mTORC1). TSC is associated with significant cognitive, psychiatric, and behavioral p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6027e08ce96274727f5f5d61d944e9e
https://doaj.org/article/8f206497b65e4d93a92d89d476e37c28
https://doaj.org/article/8f206497b65e4d93a92d89d476e37c28
Autor:
Peter J. Magill, Alexander H.C.W. Agopyan-Miu, Lisa Conyers, Kamran M. Ahmed, Sarah Threlfell, Polina Kosillo, Natalie M. Doig, Helen S. Bateup
SummarymTOR complex 1 (mTORC1) is a central coordinator of cell growth and metabolism. Mutations in regulators of mTORC1 cause syndromic disorders with a high prevalence of cognitive and psychiatric conditions. To elucidate the cellular origins of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2528c25a56131a1eb39dc4fe11146d3
https://doi.org/10.1101/376814
https://doi.org/10.1101/376814
Autor:
Aziz, Kamran M. Ahmed
Publikováno v:
Current Diabetes Reviews; December 2019, Vol. 15 Issue: 6 p486-496, 11p