Výsledky vyhledávání - "Kamran, Nazmi"

Akademický článek

GPCR/endocytosis/ERK signaling/S2R is involved in the regulation of the internalization, mitochondria-targeting and -activating properties of human salivary histatin 1

Autor: Dandan Ma, Wei Sun, Cuicui Fu, Kamran Nazmi, Enno C. I. Veerman, Richard T. Jaspers, Jan G. M. Bolscher, Floris J. Bikker, Gang Wu

Publikováno v: International Journal of Oral Science, Vol 14, Iss 1, Pp 1-15 (2022)

Abstract Human salivary histatin 1 (Hst1) exhibits a series of cell-activating properties, such as promoting cell spreading, migration, and metabolic activity. We recently have shown that fluorescently labeled Hst1 (F-Hst1) targets and activates mito

Externí odkaz: https://doaj.org/article/b333107ddf454e5aa536f9fbfb97fb17

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Akademický článek

Differential Modulation of Saliva-Derived Microcosm Biofilms by Antimicrobial Peptide LL-31 and D-LL-31

Autor: Kahena R. Soldati, Yaling Jiang, Bernd W. Brandt, Rob A. M. Exterkate, Mark J. Buijs, Kamran Nazmi, Wendy E. Kaman, Lei Cheng, Floris J. Bikker, Wim Crielaard, Daniela L. Zandim-Barcelos, Dong Mei Deng

Publikováno v: Pathogens, Vol 12, Iss 11, p 1295 (2023)

Microbiome modulation, aiming to restore a health-compatible microbiota, is a novel strategy to treat periodontitis. This study evaluated the modulation effects of antimicrobial peptide LL-31 and its D-enantiomer (D-LL-31) on saliva-derived microcosm

Externí odkaz: https://doaj.org/article/9df18b7eb06949d5aaa01d38b1428ea0

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Akademický článek

All‐trans retinoic acid and human salivary histatin‐1 promote the spreading and osteogenic activities of pre‐osteoblasts in vitro

Autor: Wei Sun, Andi Shi, Dandan Ma, Jan G. M. Bolscher, Kamran Nazmi, Enno C. I. Veerman, Floris J. Bikker, Haiyan Lin, Gang Wu

Publikováno v: FEBS Open Bio, Vol 10, Iss 3, Pp 396-406 (2020)

Cell‐based bone tissue engineering techniques utilize both osteogenic cells and biomedical materials, and have emerged as a promising approach for large‐volume bone repair. The success of such techniques is highly dependent on cell adhesion, spre

Externí odkaz: https://doaj.org/article/fbac058da915416d88f84bd7fe03edae

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Akademický článek

A rapid, non-invasive tool for periodontitis screening in a medical care setting

Autor: Martijn J. L. Verhulst, Wijnand J. Teeuw, Sergio Bizzarro, Joris Muris, Naichuan Su, Elena A. Nicu, Kamran Nazmi, Floris J. Bikker, Bruno G. Loos

Publikováno v: BMC Oral Health, Vol 19, Iss 1, Pp 1-14 (2019)

Abstract Background Since periodontitis is bi-directionally associated with several systemic diseases, such as diabetes mellitus and cardiovascular diseases, it is important for medical professionals in a non-dental setting to be able examine their p

Externí odkaz: https://doaj.org/article/1e42a618954b4d9089b123eba86f3c38

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Akademický článek

Anthrax protective antigen is a calcium-dependent serine protease

Autor: Lisanne Storm, Floris J. Bikker, Kamran Nazmi, Albert G. Hulst, Debora V. der Riet-Van Oeveren, Enno C.I. Veerman, John P. Hays, Wendy E. Kaman

Publikováno v: Virulence, Vol 9, Iss 1, Pp 1085-1091 (2018)

Bacillus anthracis secretes a three component exotoxin-complex, which contributes to anthrax pathogenesis. Formation of this complex starts with the binding of protective antigen (PA) to its cellular receptor. In this study, we report that PA is a ca

Externí odkaz: https://doaj.org/article/51ce78c8294045e09ecf67068c8d8723

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Antitumor activity of bovine lactoferrin and its derived peptides against HepG2 liver cancer cells and Jurkat leukemia cells

Autor: Izamar G. Arredondo-Beltrán, Diana A. Ramírez-Sánchez, Jesús R. Zazueta-García, Adrián Canizalez-Roman, Uriel A. Angulo-Zamudio, Jorge A. Velazquez-Roman, Jan G. M. Bolscher, Kamran Nazmi, Nidia León-Sicairos

Publikováno v: Arredondo-Beltrán, I G, Ramírez-Sánchez, D A, Zazueta-García, J R, Canizalez-Roman, A, Angulo-Zamudio, U A, Velazquez-Roman, J A, Bolscher, J G M, Nazmi, K & León-Sicairos, N 2023, ' Antitumor activity of bovine lactoferrin and its derived peptides against HepG2 liver cancer cells and Jurkat leukemia cells ', BioMetals, vol. 36, no. 3, pp. 639-655 . https://doi.org/10.1007/s10534-022-00484-4
BioMetals, 36(3), 639-655. Springer Netherlands

Liver cancer and leukemia are the fourth and first causes, respectively, of cancer death in children and adults worldwide. Moreover, cancer treatments, although beneficial, remain expensive, invasive, toxic, and affect the patient’s quality of life

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::304dd65926e23881b35b01ba491ac23d
https://doi.org/10.1007/s10534-022-00484-4

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Akademický článek

Human Salivary Histatin-1 Promotes Osteogenic Cell Spreading on Both Bio-Inert Substrates and Titanium SLA Surfaces

Autor: Wei Sun, Dandan Ma, Jan G. M. Bolscher, Kamran Nazmi, Enno C. I. Veerman, Floris J. Bikker, Ping Sun, Haiyan Lin, Gang Wu

Publikováno v: Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)

Promoting cell spreading is crucial to enhance bone healing and implant osteointegration. In this study, we investigated the stimulatory effect of human salivary histatin-1 (Hst-1) on the spreading of osteogenic cells in vitro as well as the potentia

Externí odkaz: https://doaj.org/article/08ef86f382464119b5dfb592ccee23be

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Akademický článek

D-LL-31 enhances biofilm-eradicating effect of currently used antibiotics for chronic rhinosinusitis and its immunomodulatory activity on human lung epithelial cells.

Autor: Saharut Wongkaewkhiaw, Suwimol Taweechaisupapong, Sanguansak Thanaviratananich, Jan G M Bolscher, Kamran Nazmi, Chitchanok Anutrakunchai, Sorujsiri Chareonsudjai, Sakawrat Kanthawong

Publikováno v: PLoS ONE, Vol 15, Iss 12, p e0243315 (2020)

Chronic rhinosinusitis (CRS) is a chronic disease that involves long-term inflammation of the nasal cavity and paranasal sinuses. Bacterial biofilms present on the sinus mucosa of certain patients reportedly exhibit resistance against traditional ant

Externí odkaz: https://doaj.org/article/2b0bef926a104e93a8f43dfe22117f2f

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Akademický článek

Characterization of oral polymorphonuclear neutrophils in periodontitis patients: a case-control study

Autor: Elena A. Nicu, Patrick Rijkschroeff, Eva Wartewig, Kamran Nazmi, Bruno G. Loos

Publikováno v: BMC Oral Health, Vol 18, Iss 1, Pp 1-9 (2018)

Abstract Background Maintaining oral health is a continuous and dynamic process that also involves the immune system. Polymorphonuclear neutrophils (PMNs) migrate from blood circulation and become apparent in the oral fluid. Controversies exist regar

Externí odkaz: https://doaj.org/article/24c2c13ff9c7434e8888a21a170a2946

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Novel Antiamoebic Tyrocidine-Derived Peptide against Brain-Eating Amoebae

Autor: Noor Akbar, Wendy E. Kaman, Maarten Sarink, Kamran Nazmi, Floris J. Bikker, Naveed Ahmed Khan, Ruqaiyyah Siddiqui

Publikováno v: Akbar, N, Kaman, W E, Sarink, M, Nazmi, K, Bikker, F J, Khan, N A & Siddiqui, R 2022, ' Novel Antiamoebic Tyrocidine-Derived Peptide against Brain-Eating Amoebae ', ACS Omega, vol. 7, no. 33, pp. 28797–28805 . https://doi.org/10.1021/acsomega.2c01614
ACS Omega, 7(33). American Chemical Society
ACS Omega, 7(33), 28797-28805. American Chemical Society

Acanthamoeba castellanii (A. castellanii) can cause Acanthamoeba keratitis, a sight-threatening infection, as well as a fatal brain infection termed granulomatous amoebic encephalitis, mostly in immunocompromised individuals. In contrast, Naegleria f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e417f2e4c2bb80d7b5a6d3b5dc103b1
https://doi.org/10.1021/acsomega.2c01614

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