Geriatric screening of elderly neuro-oncologic patients

Autor: Kamp, MA, Dinc, N, von Sass, C, Kwetkat, A, Baumgarten, P, Lawson McLean, A, Senft, CA

Publikováno v: 73. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Griechischen Gesellschaft für Neurochirurgie; 20220529-20220601; Köln; DOCV275 /20220525/

Objective: Assuming that elderly patients suffer more severely from side effects of the standard therapies, less aggressive treatment protocols have been established, e.g. the NOA-8 study. This practice has been questioned by several retrospective st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65c1d9a2957e2ae4ffad687639b10217

Social burden caused by neuro-oncological diseases

Autor: Kamp, MA, Dinc, N, von Sass, C, Liborius, K, Baumgarten, P, Lawson McLean, A, Senft, CA

Publikováno v: 73. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Griechischen Gesellschaft für Neurochirurgie; 20220529-20220601; Köln; DOCV295 /20220525/

Objective: Neurooncological diseases cause physical, psychological, social and possibly also spiritual distress according to the Total Pain Concept. Neurooncologists and palliative care specialists should ideally address all four areas. In practice,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9db3080e4fc415f88897c174b1d17ca9

Rapalink-1 Targets Glioblastoma Stem Cells and Acts Synergistically with Tumor Treating Fields to Reduce

Autor: Vargas-Toscano, A, Nickel, AC, Li, G, Kamp, MA, Muhammad, S, Leprivier, G, Fritsche, E, Barker, RA, Sabel, M, Steiger, HJ, Zhang, W, Hänggi, D, Kahlert, UD

Publikováno v: 72. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Polnischen Gesellschaft für Neurochirurgie; 20210606-20210609; sine loco [digital]; DOCP063 /20210604/

Objective: Glioblastoma (GBM) is a lethal disease with limited clinical treatment options available. Recently, a new inhibitor targeting the prominent cancer signaling pathway mTOR was discovered (Rapalink-1), but its therapeutic potential on stem ce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::333ff38827e50c89a2af0b2d02623231

Algorithms for perfusion measurements – trading speed for accuracy?

Autor: Fischer, I, Hänggi, D, Kamp, MA

Publikováno v: 72. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Polnischen Gesellschaft für Neurochirurgie; 20210606-20210609; sine loco [digital]; DOCP181 /20210604/

Objective: Singular value decomposition (SVD) is a fast and widely used algorithm for computing blood perfusion images from pCT, MRT, and ICG data. However, its speed is known to come at a price: The results, while mathematically correct, are not gua

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b23e48c2f27db1c30e856bbed33b70f

An in vitro technology to score therapeutic efficacy and risk-potential of substances for targeting brain tumours

Autor: Koch, K, Hartmann, R, Tsiampali, N, Uhlmann, C, He, X, Kamp, MA, Sabel, M, Barker, R, Willbold, D, Steiger, HJ, Maciaczyk, J, Kahlert, UD

Publikováno v: 71. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), 9. Joint Meeting mit der Japanischen Gesellschaft für Neurochirurgie; 20200621-20200624; sine loco [digital]; DOCP188 /20200626/

Objective: The upregulation of anabolic processes to maintain high rates of cellular turnover is considered the cancers Achilles’ heel. The intervention in altered metabolic pathways of cancer cells have emerged as a promising strategy to develop n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5b9425202745bfe31a57b870ff4e22c