Epithelial recognition and elimination against aberrant cells.

Autor: Ayukawa S; Department of Life Science and Medical Bioscience, Graduate School of Advanced Science and Engineering, Waseda University, Tokyo, Japan.; Department of Medical Sciences, School of Life Sciences, Tokyo University of Pharmacy and Life Science, Tokyo, Japan., Kamoshita N; Waseda Research Institute for Science and Engineering, Waseda University, Tokyo, Japan.; Waseda Institute for Advanced Study, Waseda University, Tokyo, Japan., Maruyama T; Department of Medical Sciences, School of Life Sciences, Tokyo University of Pharmacy and Life Science, Tokyo, Japan. maruyama@toyaku.ac.jp.; Waseda Research Institute for Science and Engineering, Waseda University, Tokyo, Japan. maruyama@toyaku.ac.jp.; Waseda Institute for Advanced Study, Waseda University, Tokyo, Japan. maruyama@toyaku.ac.jp.

Publikováno v: Seminars in immunopathology [Semin Immunopathol] 2024 Jan; Vol. 45 (4-6), pp. 521-532. Date of Electronic Publication: 2024 Feb 27.

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Genome editing of patient-derived iPSCs identifies a deep intronic variant causing aberrant splicing in hemophilia A.

Autor: Hiramoto T; Department of Biochemistry, Jichi Medical University School of Medicine, Shimotsuke, Tochigi, Japan., Inaba H; Department of Laboratory Medicine, Tokyo Medical University, Tokyo, Japan., Baatartsogt N; Department of Biochemistry, Jichi Medical University School of Medicine, Shimotsuke, Tochigi, Japan., Kashiwakura Y; Department of Biochemistry, Jichi Medical University School of Medicine, Shimotsuke, Tochigi, Japan., Hayakawa M; Department of Biochemistry, Jichi Medical University School of Medicine, Shimotsuke, Tochigi, Japan.; Center for Gene Therapy Research, Jichi Medical University, Shimotsuke, Tochigi, Japan., Kamoshita N; Department of Biochemistry, Jichi Medical University School of Medicine, Shimotsuke, Tochigi, Japan.; Center for Gene Therapy Research, Jichi Medical University, Shimotsuke, Tochigi, Japan., Nishimasu H; Structural Biology Division, Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo, Japan., Nureki O; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan., Kinai E; Department of Laboratory Medicine, Tokyo Medical University, Tokyo, Japan., Ohmori T; Department of Biochemistry, Jichi Medical University School of Medicine, Shimotsuke, Tochigi, Japan.; Center for Gene Therapy Research, Jichi Medical University, Shimotsuke, Tochigi, Japan.

Publikováno v: Blood advances [Blood Adv] 2023 Nov 28; Vol. 7 (22), pp. 7017-7027.

Successful liver transduction by re-administration of different adeno-associated virus vector serotypes in mice.

Autor: Baatartsogt N; Department of Biochemistry, Jichi Medical University School of Medicine, Shimotsuke, Tochigi, Japan., Kashiwakura Y; Department of Biochemistry, Jichi Medical University School of Medicine, Shimotsuke, Tochigi, Japan., Hiramoto T; Department of Biochemistry, Jichi Medical University School of Medicine, Shimotsuke, Tochigi, Japan., Hayakawa M; Department of Biochemistry, Jichi Medical University School of Medicine, Shimotsuke, Tochigi, Japan.; Center for Gene Therapy Research, Jichi Medical University, Shimotsuke, Tochigi, Japan., Kamoshita N; Department of Biochemistry, Jichi Medical University School of Medicine, Shimotsuke, Tochigi, Japan.; Center for Gene Therapy Research, Jichi Medical University, Shimotsuke, Tochigi, Japan., Ohmori T; Department of Biochemistry, Jichi Medical University School of Medicine, Shimotsuke, Tochigi, Japan.; Center for Gene Therapy Research, Jichi Medical University, Shimotsuke, Tochigi, Japan.

Publikováno v: The journal of gene medicine [J Gene Med] 2023 Aug; Vol. 25 (8), pp. e3505. Date of Electronic Publication: 2023 Apr 12.

The seroprevalence of neutralizing antibodies against the adeno-associated virus capsids in Japanese hemophiliacs.

Autor: Kashiwakura Y; Department of Biochemistry, Jichi Medical University School of Medicine, 3311-1 Yakushiji, Shimotsuke, Tochigi, Japan., Baatartsogt N; Department of Biochemistry, Jichi Medical University School of Medicine, 3311-1 Yakushiji, Shimotsuke, Tochigi, Japan., Yamazaki S; Clinical Research Center, Jichi Medical University Hospital, 3311-1 Yakushiji, Shimotsuke, Tochigi, Japan., Nagao A; Department of Blood Coagulation, Ogikubo Hospital, 3-1-24 Imagawa, Suginami, Tokyo 167-0035, Japan., Amano K; Department of Laboratory Medicine, Tokyo Medical University Hospital, 6-7-1, Nishishinjuku, Shinjuku, Tokyo 160-0023, Japan., Suzuki N; Department of Transfusion Medicine, Nagoya University Hospital, 65 Tsurumai, Showa, Nagoya, Aichi 466-8560, Japan., Matsushita T; Department of Transfusion Medicine, Nagoya University Hospital, 65 Tsurumai, Showa, Nagoya, Aichi 466-8560, Japan., Sawada A; Department of Respiratory Medicine and Hematology, Hyogo Medical University, 1-1 Mukogawa, Nishinomiya, Hyogo 633-8501, Japan., Higasa S; Department of Respiratory Medicine and Hematology, Hyogo Medical University, 1-1 Mukogawa, Nishinomiya, Hyogo 633-8501, Japan., Yamasaki N; Hemophilia Treatment Center, Hiroshima University Hospital, 1-2-3 Kasumi, Minami, Hiroshima, Hiroshima 734-8551, Japan., Fujii T; Hemophilia Treatment Center, Hiroshima University Hospital, 1-2-3 Kasumi, Minami, Hiroshima, Hiroshima 734-8551, Japan., Ogura T; Hemophilia Treatment Center, Shizuoka Children's Hospital, 860 Urushiyama, Aoi, Shizuoka, Shizuoka 420-8660, Japan., Takedani H; Department of Joint Surgery, IMSUT Hospital, The University of Tokyo, 4-6-1 Shirokanedai, Minato, Tokyo 108-8639, Japan., Taki M; Department of Pediatrics, St. Marianna University School of Medicine Hospital, 2-16-1 Sugao, Miyamae, Kawasaki, Kanagawa 216-8511, Japan., Matsumoto T; Department of Transfusion Medicine and Cell Therapy, Mie University Hospital, 2-174 Edobashi, Tsu, Mie 514-8507, Japan., Yamanouchi J; Division of Blood Transfusion and Cell Therapy, Ehime University Hospital, 454 Shitsukawa, Toon, Ehime 791-0204, Japan., Sakai M; Department of Pediatrics, Munakata Suikokai General Hospital, 5-7-1 Himakino, Fukutsu, Fukuoka 811-3298, Japan., Nishikawa M; Department of Clinical Laboratory, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo, Tokyo 113-8655, Japan., Yatomi Y; Department of Clinical Laboratory, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo, Tokyo 113-8655, Japan., Yada K; Department of Pediatrics, Nara Medical University Hospital, 840 Shijo, Kashihara, Nara 634-8522, Japan., Nogami K; Department of Pediatrics, Nara Medical University Hospital, 840 Shijo, Kashihara, Nara 634-8522, Japan., Watano R; Division of Genetic Therapeutics, Center for Molecular Medicine, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi 329-0498, Japan., Hiramoto T; Department of Biochemistry, Jichi Medical University School of Medicine, 3311-1 Yakushiji, Shimotsuke, Tochigi, Japan., Hayakawa M; Department of Biochemistry, Jichi Medical University School of Medicine, 3311-1 Yakushiji, Shimotsuke, Tochigi, Japan.; Center for Gene Therapy Research, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi 329-0498, Japan., Kamoshita N; Department of Biochemistry, Jichi Medical University School of Medicine, 3311-1 Yakushiji, Shimotsuke, Tochigi, Japan.; Center for Gene Therapy Research, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi 329-0498, Japan., Kume A; Clinical Research Center, Jichi Medical University Hospital, 3311-1 Yakushiji, Shimotsuke, Tochigi, Japan.; Center for Gene Therapy Research, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi 329-0498, Japan., Mizukami H; Division of Genetic Therapeutics, Center for Molecular Medicine, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi 329-0498, Japan.; Center for Gene Therapy Research, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi 329-0498, Japan., Ishikawa S; Center for Information, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi 329-0498, Japan., Sakata Y; Department of Biochemistry, Jichi Medical University School of Medicine, 3311-1 Yakushiji, Shimotsuke, Tochigi, Japan., Ohmori T; Department of Biochemistry, Jichi Medical University School of Medicine, 3311-1 Yakushiji, Shimotsuke, Tochigi, Japan.; Center for Gene Therapy Research, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi 329-0498, Japan.

Publikováno v: Molecular therapy. Methods & clinical development [Mol Ther Methods Clin Dev] 2022 Oct 27; Vol. 27, pp. 404-414. Date of Electronic Publication: 2022 Oct 27 (Print Publication: 2022).