Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Kamlesh K. Gupta"'
Autor:
Kamlesh K. Gupta, Deborah L. Donahue, Mayra J. Sandoval-Cooper, Francis J. Castellino, Victoria A. Ploplis
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Plasminogen activator inhibitor-1 (PAI-1) is known to protect mice against cardiac fibrosis. It has been speculated that PAI-1 may regulate cardiac fibrosis by inactivating urokinase-type plasminogen activator (uPA) and ultimately plasmin (P
Externí odkaz:
https://doaj.org/article/b61808fa7a1343d587e54e6e25fbad0a
Autor:
Shyam C Chaudhary, Pankaj Gupta, K K Sawlani, Kamlesh K Gupta, Abhishek Singh, Kauser Usman, Vivek Kumar, D Himanshu, Ajay Verma, Abhishek B Singh
Publikováno v:
Cureus.
Autor:
Ajay K. Patwa, null Amardeep, Virendra Atam, Pratishtha Mishra, Sumit Rungta, Anil Gangwar, Ankur Yadav, Kamlesh K. Gupta, Bhaskar Agrawal, Sanjeev K. Verma, Amit Goel
Publikováno v:
Journal of Clinical and Experimental Hepatology.
Autor:
Kamlesh K Gupta, Deborah L Donahue, Mayra J Sandoval-Cooper, Francis J Castellino, Victoria A Ploplis
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0120728 (2015)
Sepsis-induced acute kidney injury (AKI) contributes to the high mortality and morbidity in patients. Although the pathogenesis of AKI during sepsis is poorly understood, it is well accepted that plasminogen activator inhibitor-1 (PAI-1) and vitronec
Externí odkaz:
https://doaj.org/article/2ebb137a2bcc41899be7cf91e2bfd9aa
Autor:
Ankita, Singh, Shyam Chand, Chaudhary, Kamlesh K, Gupta, Kamal K, Sawlani, Abhishek, Singh, Abhishek B, Singh, Ajay K, Verma
Publikováno v:
Annals of African Medicine
Context: Obstructive sleep apnea (OSA)-related hypoxemia stimulates release of acute-phase proteins and reactive oxygen species that exacerbate insulin resistance and lipolysis and cause an augmented prothrombotic and proinflammatory state which can
Autor:
Mohibur Rahman, Ashutosh Pathak, Bruno Gonzalez-Zorn, Saheem Ahmad, Kashi N. Prasad, Avinash Singh, Shefali Gupta, Sanjay Singh, Kamlesh K. Gupta
Publikováno v:
Microbial Drug Resistance. 24:792-798
New Delhi metallo-beta-lactamase (NDM)-mediated carbapenem resistance in Pseudomonas aeruginosa and Acinetobacter baumannii is a major concern. We investigated the presence of NDM and its variants in P. aeruginosa and A. baumannii at a tertiary hospi
Publikováno v:
Biochemical and Biophysical Research Communications. 477:503-508
While inflammation is often associated with increased Plasminogen Activator Inhibitor-1 (PAI-1), the functional consequences of PAI-1 in inflammation have yet to be fully determined. The aim of this study was to establish the in vivo relevance of PAI
Autor:
Ajay Singh, Kashi N. Prasad, Abhishek Singh, Rajeev Gupta, Satyendra K. Singh, Kamlesh K. Gupta, Mukesh Tripathi
Publikováno v:
Journal of helminthology. 93(5)
Taenia solium cysticercosis is a major public health problem in developing countries. Swine cysticercosis results in economic losses for pig farmers in disease endemic areas. Consumption of cysticercotic pork leads to taeniasis in humans. Eggs excret
Autor:
Michelle D. Reid, Mulpuri Nagaraju, Manu Lopus, Donald Hamelberg, Vibha Tandon, Prasanthi Karna, Sushma R. Gundala, Ritu Aneja, Kamlesh K. Gupta, Ram Chandra Mishra, Dulal Panda
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 25:2133-2140
Noscapine is an opium-derived kinder-gentler microtubule-modulating drug, currently in Phase I/II clinical trials for cancer chemotherapy. Here, we report the synthesis of four more potent di-substituted brominated derivatives of noscapine, 9-Br-7-OH
Autor:
Mayra J. Sandoval-Cooper, Kamlesh K. Gupta, Victoria A. Ploplis, Francis J. Castellino, Deborah L. Donahue
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Plasminogen activator inhibitor-1 (PAI-1) is known to protect mice against cardiac fibrosis. It has been speculated that PAI-1 may regulate cardiac fibrosis by inactivating urokinase-type plasminogen activator (uPA) and ultimately plasmin (Pm) genera