Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Kamlesh K. Bhopale"'
Publikováno v:
Livers, Vol 3, Iss 4, Pp 597-617 (2023)
Metabolic dysfunction associated fatty liver disease (MAFLD) has been recently recognized as a new global chronic liver disease entity with non-alcoholic fatty liver disease (NAFLD) associated with overweight/obesity or type 2 diabetes mellitus (T2DM
Externí odkaz:
https://doaj.org/article/65ab0253f3744b4ea3adc25df7f363f5
Autor:
Mukund P. Srinivasan, Kamlesh K. Bhopale, Samir M. Amer, Jie Wan, Lata Kaphalia, Ghulam S. Ansari, Bhupendra S. Kaphalia
Publikováno v:
Biomolecules, Vol 9, Iss 10, p 560 (2019)
Ethanol (EtOH) metabolism itself can be a predisposing factor for initiation of alcoholic liver disease (ALD). Therefore, a dose dependent study to evaluate liver injury was conducted in hepatic alcohol dehydrogenase (ADH) deficient (ADH−) and ADH
Externí odkaz:
https://doaj.org/article/1f1df2babe1e4a779843702fd6860536
Autor:
Mukund P. Srinivasan, Kamlesh K. Bhopale, Anna A. Caracheo, Lata Kaphalia, Vsevolod L. Popov, Paul J. Boor, Bhupendra S. Kaphalia
Publikováno v:
Life Sciences. 322:121670
Autor:
Mukund P. Srinivasan, Kamlesh K. Bhopale, Anna A. Caracheo, Lata Kaphalia, Bin Gong, Vsevolod L. Popov, Paul J. Boor, G. A. Shakeel Ansari, Bhupendra S. Kaphalia
Publikováno v:
Am J Physiol Gastrointest Liver Physiol
Alcoholic chronic pancreatitis (ACP) is a fibroinflammatory disease of the pancreas. However, metabolic basis of ACP is not clearly understood. In this study, we evaluated differential pancreatic injury in hepatic alcohol dehydrogenase-deficient (ADH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46a66d4940af9ce309f2eb5b4cfc24cb
https://europepmc.org/articles/PMC8816639/
https://europepmc.org/articles/PMC8816639/
Autor:
Mukund P. Srinivasan, Appakalai N. Balamurugan, Kamlesh K. Bhopale, Gopalakrishnan Loganathan, Lata Kaphalia, Cristiana Rastellini, Bhupendra S. Kaphalia, Anna A. Caracheo
Publikováno v:
Alcohol Clin Exp Res
Background Alcoholic chronic pancreatitis (ACP) is a serious inflammatory disorder of the exocrine pancreatic gland. A previous study from this laboratory showed that ethanol (EtOH) causes cytotoxicity, dysregulates AMPKα and ER/oxidative stress sig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efc89dc0f1544209c99d0fc405690391
https://europepmc.org/articles/PMC8544284/
https://europepmc.org/articles/PMC8544284/
Autor:
Shamis Khan, Appakalai N. Balamurugan, Samir M. Amer, Mukund P. Srinivasan, Lata Kaphalia, Bhupendra S. Kaphalia, Gopalakrishnan Loganathan, Kamlesh K. Bhopale, Anna A. Caracheo
Publikováno v:
Biochem Pharmacol
Primary toxicity targets of alcohol and its metabolites in the pancreas are cellular energetics and endoplasmic reticulum (ER). Therefore, the role of AMP-Activated Protein Kinase (AMPKα) in amelioration of ethanol (EtOH)-induced pancreatic acinar c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1571b8581418b453963bc115b316227a
https://europepmc.org/articles/PMC7651864/
https://europepmc.org/articles/PMC7651864/
Autor:
Kamlesh K. Bhopale, Samir M. Amer, Lata Kaphalia, Ghulam Ansari, Bhupendra S. Kaphalia, John E. Wiktorowicz, Kizhake V. Soman
Publikováno v:
Alcoholism: Clinical and Experimental Research. 41:1675-1685
Background Chronic alcohol abuse, a major risk factor for such diseases as hepatitis and cirrhosis, impairs hepatic alcohol dehydrogenase (ADH; key ethanol [EtOH]-metabolizing enzyme). Therefore, differentially altered hepatic and plasma proteomes we
Autor:
Samir M. Amer, Lata Kaphalia, Kamlesh K. Bhopale, Kizhake V. Soman, Ghulam Ansari, John E. Wiktorowicz, Bhupendra S. Kaphalia
Publikováno v:
Pancreas. 46:806-812
ObjectivesThe aim of this study was to identify differentially expressed proteins in the pancreatic tissue of hepatic alcohol dehydrogenase–deficient deer mice fed ethanol to understand metabolic basis and mechanism of alcoholic chronic pancreatiti
Autor:
Cornelis J. Elferink, Kamlesh K. Bhopale, G. A. Shakeel Ansari, Harshica Fernando, Ramu Kakumanu, Sharon Croisant, Bhupendra S. Kaphalia, Hyunsu Ju
Publikováno v:
Mar Pollut Bull
A community-based participatory research was utilized to address the coastal community's concern regarding Deepwater Horizon oil contamination of seafood. Therefore, we analyzed polycyclic aromatic hydrocarbons (PAHs), major toxic constituents of cru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0feff629c8d6e54dbf43852265d06ef5
https://europepmc.org/articles/PMC6785834/
https://europepmc.org/articles/PMC6785834/
Autor:
Tomoki Nishiguchi, Makiko Kobayashi, Kamlesh K. Bhopale, Jong O. Lee, Lawrence C. Sowers, David N. Herndon, Sumihiro Suzuki, Fujio Suzuki, Ichiaki Ito
Publikováno v:
Nucleic Acid Therapeutics. 26:269-276
M2b macrophages (Mφ) play a major role in the increased susceptibility of subacutely burned patients, to sepsis stemming from enterococcal translocation. Certain opportunistic infections in severely burned mice have been controlled by murine CCL1 an