Výsledky vyhledávání - "Kamlesh K, Bhutani"

Synthesis of C-2 and C-3 substituted quinolines and their evaluation as anti-HIV-1 agents

Autor: Deepali Bhadane, Purvi Shah, Smita Kulkarni, Nisha Jariwala, Dharav Naik, Kamlesh K. Bhutani, Sanjay Kumar, Inder Pal Singh

Publikováno v: Bioorganic Chemistry. 80:591-601

A plenty of natural products and synthetic derivatives containing quinoline moiety have been reported to possess various pharmacological activities. Quinolines such as 2-styrylquinolines and 8-hydroxyquinolines are extensively studied for their anti-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a59244713d566088502d3a3962f745aa
https://doi.org/10.1016/j.bioorg.2018.07.016

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Dihydrocapsiate supplementation prevented high-fat diet–induced adiposity, hepatic steatosis, glucose intolerance, and gut morphological alterations in mice

Autor: Ritesh K. Baboota, Kanthi Kiran Kondepudi, Jaspreet Kaur, Pragyanshu Khare, Kamlesh K. Bhutani, Dhirendra Pratap Singh, Mahendra Bishnoi, Priyanka Mangal

Publikováno v: Nutrition Research. 51:40-56

Despite the lipolytic and thermogenic properties of capsaicin, its putative use as a weight-lowering dietary supplement has been limited because of the burning sensation caused by capsaicin when it comes in contact with mucous membranes. A potential

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2281317e39c0351ca9acbff2eeab4c8c
https://doi.org/10.1016/j.nutres.2017.11.006

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Finger millet arabinoxylan protects mice from high-fat diet induced lipid derangements, inflammation, endotoxemia and gut bacterial dysbiosis

Autor: Mahendra Bishnoi, Ravneet K. Boparai, Dhirendra Pratap Singh, Siddhartha M. Sarma, Shashank K. Singh, Kanthi Kiran Kondepudi, Vandana Bijalwan, Pragyanshu Khare, Koushik Mazumder, Shrikant Mantri, Kamlesh K. Bhutani, Priyanka Mangal, Paramdeep Singh, Jaspreet Kaur

Publikováno v: International Journal of Biological Macromolecules. 106:994-1003

Arabinoxylan (AX), a non-starch polysaccharide extracted from cereals such as wheat, rice and millets, is known to impart various health promoting effects. Our earlier study suggested that finger millet (FM) could ameliorate high fat diet (HFD)-induc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94172e28318f67035932beab62946d24
https://doi.org/10.1016/j.ijbiomac.2017.08.100

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Cinnamaldehyde supplementation prevents fasting-induced hyperphagia, lipid accumulation, and inflammation in high-fat diet-fed mice

Autor: Mahendra Bishnoi, Kamlesh K. Bhutani, Kanwaljit Chopra, Sneha Jagtap, Shyam S. Sharma, Pragyanshu Khare, Ritesh K. Baboota, Louis S. Premkumar, Yachna Jain, Priyanka Mangal, Ravneet K. Boparai, Kanthi Kiran Kondepudi

Publikováno v: BioFactors. 42:201-211

Cinnamaldehyde, a bioactive component of cinnamon, is increasingly gaining interest for its preventive and therapeutic effects against metabolic complications like type-2 diabetes. This study is an attempt to understand the effect of cinnamaldehyde i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8c1d2691ba26a5dc6d121daf5a2ee21d
https://doi.org/10.1002/biof.1265

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Synthesis and antibacterial activity of ricinoleic acid glycosides

Autor: Kamlesh K. Bhutani, Ramakrishna Kuppala, Mugunthan Govindarajan, Neeraj K. Patel, K. P. Ravindranathan Kartha, Rushikesh Tambat, Hemraj Nandanwar

Publikováno v: RSC Advances. 6:3700-3713

The antibacterial properties of twenty-eight novel ricinoleic acid glycosides synthesized by Koenigs–Knorr glycosylation are reported. Seven of them were found to show promising wide spectrum antibacterial activity against Gram positive bacteria of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5ec3276672486a42a891cb290a590d0f
https://doi.org/10.1039/c5ra20136e

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Protective effects of phyllanthin, a lignan from Phyllanthus amarus, against progression of high fat diet induced metabolic disturbances in mice

Autor: Pragyanshu Khare, Mahendra Bishnoi, Kanthi Kiran Kondepudi, Priyanka Mangal, Sneha Jagtap, Kamlesh K. Bhutani

Publikováno v: RSC Advances. 6:58343-58353

Evidence based studies have proved the efficacy of plant derived bioactives against lifestyle oriented disorders as they can be incorporated in to the diet or diet based supplements. Phyllanthin is one such lignan from Phyllanthus amarus as well as d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8fa9a2bdb4941a3dbf1cbe893b4e05f2
https://doi.org/10.1039/c6ra10774e

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2′-Hydroxy flavanone derivatives as an inhibitors of pro-inflammatory mediators: Experimental and molecular docking studies

Autor: Khemraj Bairwa, Sanjay M. Jachak, Neeraj K. Patel, Rahul P. Gangwal, Abhay T. Sangamwar, Gaurav Jaiswal, Kamlesh K. Bhutani

Publikováno v: Bioorganic & Medicinal Chemistry Letters. 25:1952-1955

2'-Hydroxy flavanone (1) was previously isolated from Mimosa pudica (L.) whole plant and was found to exhibit anti-inflammatory effects in vitro. There are also reports on anti-inflammatory properties of compounds bearing flavanone/chromone nucleus.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e12aa59db2b7243d990757ce5afbec3
https://doi.org/10.1016/j.bmcl.2015.03.025

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2,5-Diaryl-1,3,4-oxadiazoles as selective COX-2 inhibitors and anti-inflammatory agents

Autor: Sanjay M. Jachak, Vivek Kumar, Bhagirath J. Gondaliya, M. Elizabeth Sobhia, Jagdeep Grover, Neeraj K. Patel, Nirav Bhatt, Kamlesh K. Bhutani

Publikováno v: RSC Advances. 5:45535-45544

A new series of compounds comprising of 2,5-diaryl-1,3,4-oxadiazoles was synthesized and evaluated as potential COX-2 inhibitors. Compounds 6b, 6e, 6f, 7e and 7f were found to be the most potent and selective inhibitors of COX-2 (IC50 = 0.48–0.89 �

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2a922091ca2d89d911ecc69097193ecc
https://doi.org/10.1039/c5ra01428j

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