Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Kamlendra Singh Bhadoriya"'
Autor:
Kamlendra Singh Bhadoriya, Mukesh C. Sharma, Smita Sharma, Shailesh V. Jain, Mandar H. Avchar
Publikováno v:
Arabian Journal of Chemistry, Vol 7, Iss 6, Pp 924-935 (2014)
Alzheimer’s disease (AD) is a chronic neurodegenerative disease. Current therapies of AD are only symptomatic, therefore the need for the development of new therapies to treat Alzheimer’s disease effectively. To achieve this objective quantitativ
Externí odkaz:
https://doaj.org/article/dcbdecc9a9914f28aa53a84da546cbaf
Autor:
Kamlendra Singh Bhadoriya, Narender K. Kumawat, Suvarna V. Bhavthankar, Mandar H. Avchar, Dinesh M. Dhumal, Savita D. Patil, Shailesh V. Jain
Publikováno v:
Journal of Saudi Chemical Society, Vol 20, Iss S1, Pp S256-S270 (2016)
TRPM8 is now best known as a cold- and menthol-activated channel implicated in thermosensation. TRPM8 is specifically expressed in a subset of pain- and temperature-sensing neuron. TRPM8 plays a major role in the sensation of cold and cooling substan
Externí odkaz:
https://doaj.org/article/e669322dad7949698ac2017d5b6d87f6
Autor:
Vibhu Jha, Kamlendra Singh Bhadoriya
Publikováno v:
Journal of Molecular Structure. 1158:96-105
Dipeptidyl peptidase-4 (DPP-4) inhibitors are a class of newly developed antidiabetic drugs that bock DPP-4. DPP-4 is responsible for degradation of incretins harmones such as GLP-1 (Glucagon like Peptide) and GIP (Gastric inhibitory polypeptide) tha
Autor:
Mandar H. Avchar, Savita D. Patil, Shailesh V. Jain, Dinesh M. Dhumal, Narender K. Kumawat, Kamlendra Singh Bhadoriya, Suvarna V. Bhavthankar
Publikováno v:
Journal of Saudi Chemical Society, Vol 20, Iss S1, Pp S256-S270 (2016)
TRPM8 is now best known as a cold- and menthol-activated channel implicated in thermosensation. TRPM8 is specifically expressed in a subset of pain- and temperature-sensing neuron. TRPM8 plays a major role in the sensation of cold and cooling substan
Autor:
Digvijay Singh, Mrunal U. Patil, Saurabh B. Ganorkar, Kamlendra Singh Bhadoriya, Mukesh C. Sharma, Dinesh M. Dhumal
Publikováno v:
Analytical Chemistry Letters. 6:214-223
A simple, rapid and sensitive RP-HPLC-PDA method was developed and validated as per ICH guidelines for the analysis of tapentadol in bulk as well as in tablet formulation. The RP-HPLC isocratic method was developed using a column LC-GC Qualisil BDS C
Publikováno v:
Journal of Taibah University for Science. 10:107-114
Cancer is a cellular disease characterized by the progressive, persistent, abnormal, purposeless, and uncontrolled proliferation of tissues. 2D-QSAR was performed on a series of N,1,3-triphenyl-1H-pyrazole-4-carboxamides as anticancer agents to gain
Publikováno v:
Journal of Taibah University for Science. 9:521-530
Due to the AIDS crisis, development of new, selective and safe non-nucleoside reverse transcriptase inhibitors (NNRTIs) remains a high priority for medical research. The discovery of potential lead compounds by analogue based design studies was accom
Publikováno v:
Journal of Molecular Structure. 1081:466-476
Icmt enzymes are of particular importance in the post-translational modification of proteins that are involved in the regulation of cell growth. Thus, effective Icmt inhibitors may be of significant therapeutic importance in oncogenesis. To determine
Autor:
Mukesh C. Sharma, Shailesh V. Jain, Smita Sharma, Kamlendra Singh Bhadoriya, Mandar H. Avchar
Publikováno v:
Arabian Journal of Chemistry, Vol 7, Iss 6, Pp 924-935 (2014)
Alzheimer’s disease (AD) is a chronic neurodegenerative disease. Current therapies of AD are only symptomatic, therefore the need for the development of new therapies to treat Alzheimer’s disease effectively. To achieve this objective quantitativ
Publikováno v:
Medicinal Chemistry Research. 24:1272-1288
We report combined study of k-nearest neighbor, pharmacophore and 2D QSAR was performed on a series of 2,4-diaminopyrimidines dihydrofolate reductase from pyrimethamine-resistant Plasmodium falciparum as antimalarial agents to gain insights into the