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Polymorphisms of DNA repair genes are associated with colorectal cancer in patients with Lynch syndrome.

Autor: Kamiza, Abram B.¹, Hsieh, Ling‐Ling², Tang, Reiping^3,4, Chien, Huei‐Tzu^2,5, Lai, Chih‐Hsiung², Chiu, Li‐Ling^2,5, Lo, Tsai‐Ping⁶, Hung, Kuan‐Yi⁶, You, Jeng‐Fu^3,4, Wang, Wen‐Chang⁷, Hsiung, Chao A.⁶ hsiung@nhri.org.tw, Yeh, Chih‐Ching^1,8 ccyeh@tmu.edu.tw

Publikováno v: Molecular Genetics & Genomic Medicine. Jul2018, Vol. 6 Issue 4, p533-540. 8p.

Transferability of genetic risk scores in African populations.

Autor: Kamiza AB; The African Computational Genomics (TACG) Research Group, MRC/UVRI and LSHTM, Entebbe, Uganda.; Malawi Epidemiology and Intervention Research Unit, Lilongwe, Karonga, Malawi.; Sydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa., Toure SM; The African Computational Genomics (TACG) Research Group, MRC/UVRI and LSHTM, Entebbe, Uganda.; African Centre of Excellence in Bioinformatics, University of Science and Technologies of Bamako, Bamako, Mali., Vujkovic M; Department of Pathology and Molecular Medicine, McMaster University, Michael G. DeGroote School of Medicine, Hamilton, Ontario, Canada., Machipisa T; Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, USA.; Hatter Institute for Cardiovascular Diseases Research in Africa (HICRA), Department of Medicine, University of Cape Town, Cape Town, South Africa.; Population Health Research Institute, David Braley Cardiac, Vascular and Stroke Research Institute, Hamilton, Ontario, Canada., Soremekun OS; The African Computational Genomics (TACG) Research Group, MRC/UVRI and LSHTM, Entebbe, Uganda., Kintu C; The African Computational Genomics (TACG) Research Group, MRC/UVRI and LSHTM, Entebbe, Uganda., Corpas M; Cambridge Precision Medicine Limited, ideaSpace, University of Cambridge Biomedical Innovation Hub, Cambridge, United Kingdom.; Institute of Continuing Education, Madingley Hall, University of Cambridge, Cambridge, UK.; Facultad de Ciencias de la Salud, Universidade Internacional de La Rioja, Madrid, Spain., Pirie F; Department of Diabetes and Endocrinology, University of KwaZulu-Natal, Durban, South Africa., Young E; Omnigen Biodata Ltd, Cambridge, UK., Gill D; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom.; Clinical Pharmacology and Therapeutics Section, Institute of Medical and Biomedical Education and Institute for Infection and Immunity, St George's, University of London, London, UK., Sandhu MS; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom., Kaleebu P; MRC/UVRI and LSHTM, Entebbe, Uganda., Nyirenda M; MRC/UVRI and LSHTM, Entebbe, Uganda., Motala AA; Department of Diabetes and Endocrinology, University of KwaZulu-Natal, Durban, South Africa., Chikowore T; Sydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa. tinashe.chikowore1@wits.ac.za.; MRC/Wits Developmental Pathways for Health Research Unit, Department of Paediatrics, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa. tinashe.chikowore1@wits.ac.za., Fatumo S; The African Computational Genomics (TACG) Research Group, MRC/UVRI and LSHTM, Entebbe, Uganda. segun.fatumo@lshtm.ac.uk.; MRC/UVRI and LSHTM, Entebbe, Uganda. segun.fatumo@lshtm.ac.uk.; London School of Hygiene and Tropical Medicine, London, UK. segun.fatumo@lshtm.ac.uk.; H3Africa Bioinformatics Network (H3ABioNet) Node, Centre for Genomics Research and Innovation, NABDA/FMST, Abuja, Nigeria. segun.fatumo@lshtm.ac.uk.

Publikováno v: Nature medicine [Nat Med] 2022 Jun; Vol. 28 (6), pp. 1163-1166. Date of Electronic Publication: 2022 Jun 02.