Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Kamilla Westarp Zornhagen"'
Autor:
Freja Albjerg Venning, Kamilla Westarp Zornhagen, Lena Wullkopf, Jonas Sjölund, Carmen Rodriguez-Cupello, Pontus Kjellman, Mikkel Morsing, Morteza Chalabi Hajkarim, Kyoung Jae Won, Janine Terra Erler, Chris Denis Madsen
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-21 (2021)
Abstract Background Cancer-associated fibroblasts (CAFs) comprise a heterogeneous population of stromal cells within the tumour microenvironment. CAFs exhibit both tumour-promoting and tumour-suppressing functions, making them exciting targets for im
Externí odkaz:
https://doaj.org/article/a5982df9dfdb4c37a2ed3833290a7ddd
Autor:
Kamilla Westarp Zornhagen, Malene M. Clausen, Anders E. Hansen, Ian Law, Fintan J. McEvoy, Svend A. Engelholm, Andreas Kjær, Annemarie T. Kristensen
Publikováno v:
Diagnostics, Vol 5, Iss 3, Pp 372-382 (2015)
Glycolysis, hypoxia, and proliferation are important factors in the tumor microenvironment contributing to treatment-resistant aggressiveness. Imaging these factors using combined functional positron emission tomography and computed tomography can po
Externí odkaz:
https://doaj.org/article/f6dee9656953426aa1b6e4a371499e6b
Autor:
Kamilla Westarp Zornhagen, Anders E Hansen, Jytte Oxboel, Andreas E Clemmensen, Henrik H El Ali, Annemarie T Kristensen, Andreas Kjær
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0141379 (2015)
Tumour microenvironment heterogeneity is believed to play a key role in cancer progression and therapy resistance. However, little is known about micro regional distribution of hypoxia, glycolysis and proliferation in spontaneous solid tumours. The o
Externí odkaz:
https://doaj.org/article/fe7be8303575498db6223a9ff4f5695c
Autor:
Anu Laitala, Sarah McNeilly, Sina Zendehroud, Lene B. Oddershede, Maria Rafaeva, Wilhelm Bloch, Monica Nicolau, Stefanie Sudhop, Stefanie Kiderlen, Janine T. Erler, Alejandro E Mayorca-Guiliani, Frank Suhr, Carina Prein, Lutz Fleischhauer, Kamilla Westarp Zornhagen, Benjamin Furtwängler, Chris D. Madsen, Denise Nikodemus, Tom Van Agtmael, Kyoung-Jae Won, Hyobin Kim, Erwin M. Schoof, Manuel Koch, Eleni Maniati, Hauke Clausen-Schaumann, Oliver M. T. Pearce, Sebastian R. Nielsen, Lena Wullkopf, Roland R. Netz, Bo T. Porse, Raphael Reuten
Publikováno v:
Reuten, R, Zendehroud, S, Nicolau, M, Fleischhauer, L, Laitala, A, Kiderlen, S, Nikodemus, D, Wullkopf, L, Nielsen, S R, McNeilly, S, Prein, C, Rafaeva, M, Schoof, E M, Furtwängler, B, Porse, B T, Kim, H, Won, K J, Sudhop, S, Zornhagen, K W, Suhr, F, Maniati, E, Pearce, O M T, Koch, M, Oddershede, L B, Van Agtmael, T, Madsen, C D, Mayorca-Guiliani, A E, Bloch, W, Netz, R R, Clausen-Schaumann, H & Erler, J T 2021, ' Basement membrane stiffness determines metastases formation ', Nature Materials, vol. 20, pp. 892-903 . https://doi.org/10.1038/s41563-020-00894-0
Nature Materials
Reuten, R, Zendehroud, S, Nicolau, M, Fleischhauer, L, Laitala, A, Kiderlen, S, Nikodemus, D, Wullkopf, L, Nielsen, S R, Mcneilly, S, Prein, C, Rafaeva, M, Schoof, E M, Furtwängler, B, Porse, B T, Kim, H, Won, K J, Sudhop, S, Zornhagen, K W, Suhr, F, Maniati, E, Pearce, O M T, Koch, M, Oddershede, L B, Van Agtmael, T, Madsen, C D, Mayorca-guiliani, A E, Bloch, W, Netz, R R, Clausen-schaumann, H & Erler, J T 2021, ' Basement membrane stiffness determines metastases formation ', Nature Materials, vol. 20, pp. 892–903 . https://doi.org/10.1038/s41563-020-00894-0
Nature Materials
Reuten, R, Zendehroud, S, Nicolau, M, Fleischhauer, L, Laitala, A, Kiderlen, S, Nikodemus, D, Wullkopf, L, Nielsen, S R, Mcneilly, S, Prein, C, Rafaeva, M, Schoof, E M, Furtwängler, B, Porse, B T, Kim, H, Won, K J, Sudhop, S, Zornhagen, K W, Suhr, F, Maniati, E, Pearce, O M T, Koch, M, Oddershede, L B, Van Agtmael, T, Madsen, C D, Mayorca-guiliani, A E, Bloch, W, Netz, R R, Clausen-schaumann, H & Erler, J T 2021, ' Basement membrane stiffness determines metastases formation ', Nature Materials, vol. 20, pp. 892–903 . https://doi.org/10.1038/s41563-020-00894-0
The basement membrane (BM) is a special type of extracellular matrix and presents the major barrier cancer cells have to overcome multiple times to form metastases. Here we show that BM stiffness is a major determinant of metastases formation in seve
Autor:
Kamilla Westarp Zornhagen, Chris D. Madsen, Kyoung-Jae Won, Lena Wullkopf, Freja Albjerg Venning, Morteza Chalabi Hajkarim, Janine Tera Erler
Cancer-associated fibroblasts (CAFs) comprise a heterogeneous population of stromal cells within the tumour microenvironment. CAFs exhibit both tumour-promoting and tumour-suppressing functions, making them exciting targets for improving cancer treat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19077d2bf39af35d18bcb89ff471032a
https://doi.org/10.1101/2020.05.05.070607
https://doi.org/10.1101/2020.05.05.070607
Autor:
Dina S. Grønseth, Raphael Reuten, Ulrik Lassen, Martin Højgaard, Kamilla Westarp Zornhagen, Manja Idorn, Chris D. Madsen, Marina Crespo, Kristoffer Staal Rohrberg, Christian B. Brøchner, Maria Rafaeva, Janine T. Erler, Adina R. D. Jensen, Alejandro E Mayorca-Guiliani, Oliver Willacy, Per thor Straten, Thomas Hartvig Lindkær Jensen, Edward R. Horton, Sebastian R. Nielsen, Iben Spanggaard
Publikováno v:
Rafaeva, M, Horton, E R, Jensen, A R D, Madsen, C D, Reuten, R, Willacy, O, Brøchner, C B, Jensen, T H, Zornhagen, K W, Crespo, M, Grønseth, D S, Nielsen, S R, Idorn, M, Straten, P T, Rohrberg, K, Spanggaard, I, Højgaard, M, Lassen, U, Erler, J T & Mayorca-Guiliani, A E 2022, ' Modeling Metastatic Colonization in a Decellularized Organ Scaffold-Based Perfusion Bioreactor ', Advanced Healthcare Materials, vol. 11, no. 1, 2100684 . https://doi.org/10.1002/adhm.202100684
Metastatic cancer spread is responsible for most cancer-related deaths. To colonize a new organ, invading cells adapt to, and remodel, the local extracellular matrix (ECM), a network of proteins and proteoglycans underpinning all tissues, and a criti
Autor:
Annemarie T. Kristensen, Svend Aage Engelholm, Kamilla Westarp Zornhagen, Andreas Kjaer, Anders Elias Hansen, Fintan J. McEvoy, Malene Martini Clausen, Ian Law
Publikováno v:
Diagnostics
Zornhagen, K, Clausen, M, Hansen, A E, Law, I, McEvoy, F, Engelholm, S, Kjær, A & Kristensen, A 2015, ' Use of Molecular Imaging Markers of Glycolysis, Hypoxia and Proliferation ( 18 F-FDG, 64 Cu-ATSM and 18 F-FLT) in a Dog with Fibrosarcoma : The Importance of Individualized Treatment Planning and Monitoring ', Diagnostics, vol. 5, no. 3, pp. 372-382 . https://doi.org/10.3390/diagnostics5030372
Zornhagen, K W, Clausen, M M, Hansen, A E, Law, I, McEvoy, F, Engelholm, S A, Kjær, A & Kristensen, A T 2015, ' Use of molecular maging markers of glycolysis, hypoxia and proliferation ( 18 F-FDG, 64 Cu-ATSM and 18 F-FLT) in a dog with fibrosarcoma : the importance of individualized treatment planning and monitoring ', Diagnostics, vol. 5, no. 3, pp. 372-382 . https://doi.org/10.3390/diagnostics5030372
Diagnostics, Vol 5, Iss 3, Pp 372-382 (2015)
Zornhagen, K, Clausen, M, Hansen, A E, Law, I, McEvoy, F, Engelholm, S, Kjær, A & Kristensen, A 2015, ' Use of Molecular Imaging Markers of Glycolysis, Hypoxia and Proliferation ( 18 F-FDG, 64 Cu-ATSM and 18 F-FLT) in a Dog with Fibrosarcoma : The Importance of Individualized Treatment Planning and Monitoring ', Diagnostics, vol. 5, no. 3, pp. 372-382 . https://doi.org/10.3390/diagnostics5030372
Zornhagen, K W, Clausen, M M, Hansen, A E, Law, I, McEvoy, F, Engelholm, S A, Kjær, A & Kristensen, A T 2015, ' Use of molecular maging markers of glycolysis, hypoxia and proliferation ( 18 F-FDG, 64 Cu-ATSM and 18 F-FLT) in a dog with fibrosarcoma : the importance of individualized treatment planning and monitoring ', Diagnostics, vol. 5, no. 3, pp. 372-382 . https://doi.org/10.3390/diagnostics5030372
Diagnostics, Vol 5, Iss 3, Pp 372-382 (2015)
Glycolysis, hypoxia, and proliferation are important factors in the tumor microenvironment contributing to treatment-resistant aggressiveness. Imaging these factors using combined functional positron emission tomography and computed tomography can po
Autor:
J. Oxboel, Kamilla Westarp Zornhagen, Andreas Kjaer, Annemarie T. Kristensen, Anders Elias Hansen
Publikováno v:
Europe PubMed Central
Quantitative real-time reverse transcription polymerase chain reaction (RT-qPCR) is a sensitive technique for quantifying gene expression. Stably expressed reference genes are necessary for normalization of RT-qPCR data. Only a few articles have been
Autor:
Betina Børresen, Malene Martini Clausen, Anders Elias Hansen, Kamilla Westarp Zornhagen, Annemarie Thuri Kristensen, Svend Aage Engelholm, Andreas Kjaer
Publikováno v:
Børresen, B, Clausen, M M, Hansen, A E, Zornhagen, K W, Kristensen, A T, Engelholm, S A & Kjær, A 2014, ' Hunde med spontan cancer indgår i translationel forskning ', Ugeskrift for Laeger, bind 176, nr. 14, V01130041, s. 1304-1307 .
University of Copenhagen
Technical University of Denmark Orbit
University of Copenhagen
Technical University of Denmark Orbit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::4f29f76d01640192d8f2ea71498131da
https://orbit.dtu.dk/en/publications/c7cb04ef-2fb4-426f-ae5c-e1745783d07b
https://orbit.dtu.dk/en/publications/c7cb04ef-2fb4-426f-ae5c-e1745783d07b
Autor:
Andreas Clemmensen, Kamilla Westarp Zornhagen, Jytte Oxboel, Annemarie T. Kristensen, Anders Elias Hansen, Henrik H. El Ali, Andreas Kjaer
Publikováno v:
Zornhagen, K W, Hansen, A E, Oxbøl, J, Clemmensen, A E, El Ali, H H, Kristensen, A T & Kjær, A 2015, ' Micro regional heterogeneity of 64 Cu-ATSM and 18 F-FDG uptake in canine soft tissue sarcomas : relation to cell proliferation, hypoxia and glycolysis ', PloS one, vol. 10, no. 10, e0141379 . https://doi.org/10.1371/journal.pone.0141379
Zornhagen, K W, Hansen, A E, Oxboel, J, Clemmensen, A E, El Ali, H H, Kristensen, A T, Kjær, A & Chen, C-T (ed.) 2015, ' Micro Regional Heterogeneity of 64 Cu-ATSM and 18 F-FDG Uptake in Canine Soft Tissue Sarcomas : Relation to Cell Proliferation, Hypoxia and Glycolysis ', P L o S One, vol. 10, no. 10, e0141379 . https://doi.org/10.1371/journal.pone.0141379
PLoS ONE, Vol 10, Iss 10, p e0141379 (2015)
PLoS ONE
Zornhagen, K W, Hansen, A E, Oxboel, J, Clemmensen, A E, El Ali, H H, Kristensen, A T, Kjær, A & Chen, C-T (ed.) 2015, ' Micro Regional Heterogeneity of 64 Cu-ATSM and 18 F-FDG Uptake in Canine Soft Tissue Sarcomas : Relation to Cell Proliferation, Hypoxia and Glycolysis ', P L o S One, vol. 10, no. 10, e0141379 . https://doi.org/10.1371/journal.pone.0141379
PLoS ONE, Vol 10, Iss 10, p e0141379 (2015)
PLoS ONE
OBJECTIVES: Tumour microenvironment heterogeneity is believed to play a key role in cancer progression and therapy resistance. However, little is known about micro regional distribution of hypoxia, glycolysis and proliferation in spontaneous solid tu