Zobrazeno 1 - 10 of 28 pro vyhledávání: '"Kamilla Mundbjerg"'
1
Akademický článek
The Efficacy and Safety of Multiple Dose Regimens of Kudzu (Pueraria lobata) Root Extract on Bone and Cartilage Turnover and Menopausal Symptoms
Autor: Asger Reinstrup Bihlet, Inger Byrjalsen, Jeppe Ragnar Andersen, Simone Faurholt Simonsen, Kamilla Mundbjerg, Betina Helmer, Bente Juel Riis, Morten Asser Karsdal, Claus Christiansen
Publikováno v: Frontiers in Pharmacology, Vol 12 (2021)
Background: Menopause is associated with detrimental changes in turnover of bone and cartilage and a variety of symptoms with negative impact on the quality of life. Naturally occurring isoflavones from Radix Pueraria lobata, Kudzu root, may possess
Externí odkaz: https://doaj.org/article/fe2b4aa4d4d844318a655c0fe7a44ea6
Zobrazit plný text záznamu
2
Akademický článek
Top2 and Sgs1-Top3 Act Redundantly to Ensure rDNA Replication Termination.
Autor: Kamilla Mundbjerg, Signe W Jørgensen, Jacob Fredsøe, Ida Nielsen, Jakob Madsen Pedersen, Iben Bach Bentsen, Michael Lisby, Lotte Bjergbaek, Anni H Andersen
Publikováno v: PLoS Genetics, Vol 11, Iss 12, p e1005697 (2015)
Faithful DNA replication with correct termination is essential for genome stability and transmission of genetic information. Here we have investigated the potential roles of Topoisomerase II (Top2) and the RecQ helicase Sgs1 during late stages of rep
Externí odkaz: https://doaj.org/article/32bd97e7f96641f2b2a8da280bc44038
Zobrazit plný text záznamu
3
Akademický článek
DNA Topoisomerases maintain promoters in a state competent for transcriptional activation in Saccharomyces cerevisiae.
Autor: Jakob Madsen Pedersen, Jacob Fredsoe, Morten Roedgaard, Lotte Andreasen, Kamilla Mundbjerg, Mogens Kruhøffer, Marie Brinch, Mikkel Heide Schierup, Lotte Bjergbaek, Anni Hangaard Andersen
Publikováno v: PLoS Genetics, Vol 8, Iss 12, p e1003128 (2012)
To investigate the role of DNA topoisomerases in transcription, we have studied global gene expression in Saccharomyces cerevisiae cells deficient for topoisomerases I and II and performed single-gene analyses to support our findings. The genome-wide
Externí odkaz: https://doaj.org/article/18b9edce25cc4064a9ab2b67b8b5f8da
Zobrazit plný text záznamu
6
Hypermethylation of the GABRE∼miR-452∼miR-224 Promoter in Prostate Cancer Predicts Biochemical Recurrence after Radical Prostatectomy
Autor: Christian Arsov, Karina Dalsgaard Sørensen, Marie Stampe Ostenfeld, Michael Borre, Siri H. Strand, Helle Kristensen, Kasper Thorsen, Tapio Visakorpi, Martin Mørck Mortensen, Søren Svane Hoyer, Torben F. Ørntoft, Kamilla Mundbjerg, Peter J. Wild, Henrik Grönberg, Wolfgang Goering, Lars Egevad, Christa Haldrup, Johan Lindberg
Publikováno v: Kristensen, H, Haldrup, C, Strand, S, Mundbjerg, K, Mortensen, M M, Thorsen, K, Ostenfeld, M S, Wild, P J, Arsov, C, Goering, W, Visakorpi, T, Egevad, L, Lindberg, J, Grönberg, H, Høyer, S, Borre, M, Orntoft, T F & Sørensen, K D 2014, ' Hypermethylation of the GABRE~miR-452~miR-224 Promoter in Prostate Cancer Predicts Biochemical Recurrence after Radical Prostatectomy ', Clinical Cancer Research, vol. 20, no. 8, pp. 2169-81 . https://doi.org/10.1158/1078-0432.CCR-13-2642
Purpose: Available tools for prostate cancer diagnosis and prognosis are suboptimal and novel biomarkers are urgently needed. Here, we investigated the regulation and biomarker potential of the GABRE∼miR-452∼miR-224 genomic locus. Experimental De
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42881e018f180daa7c9010098feb95ff
https://doi.org/10.1158/1078-0432.ccr-13-2642
Zobrazit plný text záznamu
7
Identifying aggressive prostate cancer foci using a DNA methylation classifier
Autor: Gangning Liang, Vinay Duddalwar, Mariana C. Stern, Osamu Ukimura, Christopher E. Duymich, Daniel J. Weisenberger, Inderbir S. Gill, Monish Aron, John D. Carpten, Manju Aron, Kamilla Mundbjerg, Peter A. Jones, Kimberly D. Siegmund, Peter W. Nichols, Torben F. Ørntoft, Mehrdad Alemozaffar, Parkash S. Gill, Karina Dalsgaard Sørensen, Sameer Chopra, Ranjani Lakshminarasimhan
Publikováno v: Genome Biology
Mundbjerg, K, Chopra, S, Alemozaffar, M, Duymich, C, Lakshminarasimhan, R, Nichols, P W, Aron, M, Siegmund, K D, Ukimura, O, Aron, M, Stern, M C, Gill, P, Carpten, J D, Ørntoft, T F, Sørensen, K D, Weisenberger, D J, Jones, P A, Duddalwar, V, Gill, I S & Liang, G 2017, ' Identifying aggressive prostate cancer foci using a DNA methylation classifier ', Genome Biology, vol. 18, no. 1, pp. 3 . https://doi.org/10.1186/s13059-016-1129-3
Background Slow-growing prostate cancer (PC) can be aggressive in a subset of cases. Therefore, prognostic tools to guide clinical decision-making and avoid overtreatment of indolent PC and undertreatment of aggressive disease are urgently needed. PC
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::549e6befa66597750fe16ed50a0a69b3
https://pubmed.ncbi.nlm.nih.gov/28081708
Zobrazit plný text záznamu
8
Heterogeneous patterns of DNA methylation-based field effects in histologically normal prostate tissue from cancer patients
Autor: Torben F. Ørntoft, Gangning Liang, Søren Høyer, Mia Moller, Christa Haldrup, Karina Dalsgaard Sørensen, Siri H. Strand, Michael Borre, Inderbir S. Gill, Kamilla Mundbjerg
Publikováno v: Scientific Reports
Møller, M, Strand, S, Mundbjerg, K, Liang, G, Gill, I S, Haldrup, C, Borre, M, Høyer, S, Ørntoft, T F & Sørensen, K D 2017, ' Heterogeneous patterns of DNA methylation-based field effects in histologically normal prostate tissue from cancer patients ', Scientific Reports, vol. 7, 40636 . https://doi.org/10.1038/srep40636
Prostate cancer (PC) diagnosis is based on histological evaluation of prostate needle biopsies, which have high false negative rates. Here, we investigated if cancer-associated epigenetic field effects in histologically normal prostate tissue may be
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c0d0aff4f7b977dcc0a2da8e26841cc
https://pubmed.ncbi.nlm.nih.gov/28084441
Zobrazit plný text záznamu
10
Bivalent Regions of Cytosine Methylation and H3K27 Acetylation Suggest an Active Role for DNA Methylation at Enhancers
Autor: Karina Dalsgaard Sørensen, Peter A. Jones, Gangning Liang, Fides D. Lay, Kamilla Mundbjerg, Jessica Charlet, Christopher E. Duymich
Publikováno v: Charlet, J, Duymich, C E, Lay, F D, Mundbjerg, K, Dalsgaard Sørensen, K, Liang, G & Jones, P A 2016, ' Bivalent Regions of Cytosine Methylation and H3K27 Acetylation Suggest an Active Role for DNA Methylation at Enhancers ', Molecular Cell, vol. 62, no. 3, pp. 422-31 . https://doi.org/10.1016/j.molcel.2016.03.033
The role of cytosine methylation in the structure and function of enhancers is not well understood. In this study, we investigate the role of DNA methylation at enhancers by comparing the epigenomes of the HCT116 cell line and its highly demethylated
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e246e2e599b32c534a7e4f6872fd97ec
https://pure.au.dk/portal/da/publications/bivalent-regions-of-cytosine-methylation-and-h3k27-acetylation-suggest-an-active-role-for-dna-methylation-at-enhancers(f7a661f5-42a7-411a-bef1-095fc3d37b16).html
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje