Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Kamilia, Abdelraouf"'
Autor:
Shana R. Leopold, Kamilia Abdelraouf, David P. Nicolau, Hanako Agresta, Jethro Johnson, Kathleen Teter, Wm Michael Dunne, David Broadwell, Alex van Belkum, Lisa M. Schechter, Erica J. Sodergren, George M. Weinstock
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
There is a current need for enhancing our insight in the effects of antimicrobial treatment on the composition of human microbiota. Also, the spontaneous restoration of the microbiota after antimicrobial treatment requires better understanding. This
Externí odkaz:
https://doaj.org/article/12362080b677470880ac6108c121e6ef
Autor:
Kamilia Abdelraouf, David P Nicolau
Publikováno v:
Journal of Antimicrobial Chemotherapy. 78:692-702
BackgroundCefepime/taniborbactam is a cephalosporin/bicyclic boronate β-lactamase inhibitor combination in clinical development for nosocomial pneumonia due to MDR Gram-negative bacteria. A murine pneumonia model was used to characterize cefepime/ta
Publikováno v:
Open Forum Infectious Diseases. 9
Background Sulbactam (SUL), available in the USA as ampicillin-sulbactam, is a first line treatment for Acinetobacter baumannii infections. SUL is bactericidal against A. baumannii through affinity to penicillin-binding proteins with no synergy upon
Autor:
Kamilia Abdelraouf, Christian M Gill, Matthew Gethers, Giusy Tiseo, Marco Falcone, Francesco Menichetti, David P Nicolau
Publikováno v:
Open Forum Infectious Diseases. 9
Background In vitro-in vivo discordance in the activity of β-lactams against MBL-producing Enterobacterales has been described. This discordance is likely attributed to the supra-physiologic zinc level in the in vitro testing media, which facilitate
Autor:
Andrew J Fratoni, Angela Berry, Haitao Yuan, Xiao Liu, Xi Chen, Yuchuan Wu, David P Nicolau, Kamilia Abdelraouf
Publikováno v:
Open Forum Infectious Diseases. 9
Background Imipenem (IPM)/XNW4107 is a novel β-lactam/β-lactamase inhibitor with in vitro activity against serine carbapenemase-producing Acinetobacter baumannii, Pseudomonas aeruginosa and Enterobacterales. Herein, we evaluated the in vivo activit
Autor:
Mohamed I. Nounou, Fatema ElAmrawy, Nada Ahmed, Kamilia Abdelraouf, Satyanarayana Goda, Hussaini Syed-Sha-Qhattal
Publikováno v:
Breast Cancer: Basic and Clinical Research, Vol 2015, Iss Suppl. 2, Pp 17-34 (2015)
Externí odkaz:
https://doaj.org/article/a3ebca128cd4437a81dd38ee22f964d1
Publikováno v:
Journal of Antimicrobial Chemotherapy. 76:993-1000
Objectives WCK 4282, high-dose cefepime/tazobactam, possesses potent in vitro activity against Gram-negative organisms including ESBL- and cephalosporinase-harbouring strains. The purpose of this evaluation was to investigate the in vivo activity of
Autor:
Christian M. Gill, Kamilia Abdelraouf, Merime Oota, Rio Nakamura, Miho Kuroiwa, Yoshino Ishioka, Miki Takemura, Yoshinori Yamano, David P. Nicolau
Publikováno v:
JAC-Antimicrobial Resistance. 4
Objectives This study evaluated the sustained kill and potential for resistance development of Acinetobacter baumannii exposed to human-simulated exposure of cefiderocol over 72 h in in vitro and in vivo infection models. Methods Seven A. baumannii i
Publikováno v:
J Antimicrob Chemother
ObjectivesCefepime/taniborbactam is a cephalosporin/cyclic boronate β-lactamase inhibitor combination under development for the treatment of infections due to MDR Enterobacterales and Pseudomonas aeruginosa. Using a neutropenic murine thigh infectio
Publikováno v:
Journal of Antimicrobial Chemotherapy. 75:997-1005
BackgroundMBLs are a major contributor to β-lactam resistance when tested using CAMHB. Despite in vitro resistance, positive outcomes have been reported in MBL-infected patients following carbapenem treatment. The impact of physiological zinc concen