Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Kamila Rząd"'
Autor:
Kamila Rząd, Iwona Gabriel, Ewa Paluszkiewicz, Aleksandra Kuplińska, Mateusz Olszewski, Agnieszka Chylewska, Aleksandra M. Dąbrowska, Katarzyna Kozłowska-Tylingo
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-19 (2024)
Abstract Fungal pathogens are considered as serious factors for deadly diseases and are a case of medical concern. Invasive fungal infections also complicate the clinical course of COVID-19, leading to a significant increase in mortality. Furthermore
Externí odkaz:
https://doaj.org/article/b58d5d900a014aeca8dec4150e53f28e
Publikováno v:
Biomolecules, Vol 14, Iss 10, p 1315 (2024)
L-methionine (L-Met) is one of the nine proteinogenic amino acids essential for humans since, in human cells, there are no complete pathways for its biosynthesis from simple precursors. L-Met plays a crucial role in cellular function as it is require
Externí odkaz:
https://doaj.org/article/ad19452ab45140848ad3548f855a439c
Autor:
Kamila Rząd, Rachel Ioannidi, Panagiotis Marakos, Nicole Pouli, Mateusz Olszewski, Ioannis K. Kostakis, Iwona Gabriel
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract With the current massive increases in drug-resistant microbial infection as well as the significant role of fungal infections in the death toll of COVID-19, discovering new antifungals is extremely important. Natural and synthetic xanthones
Externí odkaz:
https://doaj.org/article/2b29057202b0428a8ba398241f6921ad
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 14, p 7763 (2022)
Due to the apparent similarity of fungal and mammalian metabolic pathways, the number of established antifungal targets is low, and the identification of novel ones is highly desirable. The results of our studies, presented in this work, indicate tha
Externí odkaz:
https://doaj.org/article/ebd051d138a04f8496a7cfe51fe06896
Autor:
Kamila Rząd, Ewa Paluszkiewicz, Damian Neubauer, Mateusz Olszewski, Katarzyna Kozłowska-Tylingo, Wojciech Kamysz, Iwona Gabriel
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 24, p 13190 (2021)
Acridine cell-penetrating peptide conjugates are an extremely important family of compounds in antitumor chemotherapy. These conjugates are not so widely analysed in antimicrobial therapy, although bioactive peptides could be used as nanocarriers to
Externí odkaz:
https://doaj.org/article/df917113f34f4edfa1ef5db637a7da39
Publikováno v:
Pathogens, Vol 10, Iss 2, p 189 (2021)
In the last few years, increasing importance is attached to problems caused by fungal pathogens. Current methods of preventing fungal infections remain unsatisfactory. There are several antifungal compounds which are highly effective in some cases, h
Externí odkaz:
https://doaj.org/article/c6acd40ef8854a9da44a5cac9144dc38
Autor:
Kamila Rząd, Aleksandra Kuplińska
Publikováno v:
Amino Acids
Fungi cause death of over 1.5 million people every year, while cutaneous mycoses are among the most common infections in the world. Mycoses vary greatly in severity, there are long-term skin (ringworm), nail or hair infections (tinea capitis), recurr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2d7551162464b5f019443a6738a0e2b
https://pubmed.ncbi.nlm.nih.gov/34081205
https://pubmed.ncbi.nlm.nih.gov/34081205
Publikováno v:
Bioorganicmedicinal chemistry letters. 35
Fungal resistance remains a significant threat and a leading cause of death worldwide. Thus, overcoming microbial infections have again become a serious clinical problem. Although acridine derivatives are widely analyzed as anticancer agents, only a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::189070b18974f48aa7f0d14d08ba7271
https://pubmed.ncbi.nlm.nih.gov/33486051
https://pubmed.ncbi.nlm.nih.gov/33486051
Publikováno v:
Fungal Genetics and Biology. 110:26-37
Amino acids constitute the key sources of nitrogen for growth of Candida albicans. In order to survive inside the host in different and rapidly changing environments, this fungus must be able to adapt via its expression of genes for amino acid metabo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7e3c4ef29073188c9594f7176166050
https://doi.org/10.1016/j.fgb.2017.11.009
https://doi.org/10.1016/j.fgb.2017.11.009
Autor:
Kamila Rząd, Iwona Gabriel
Publikováno v:
Acta Biochimica Polonica. 62:903-912
Aminoadipate aminotransferase (AmAA) is an enzyme of α-aminoadipate pathway (AAP) for L-lysine biosynthesis. AmAA may also participated in biosynthesis or degradation of aromatic amino acids and in D-tryptophan based pigment production. The AAP is u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6085c199f489e4ece89a7da5d9d6e4b
https://doi.org/10.18388/abp.2015_1158
https://doi.org/10.18388/abp.2015_1158